Protein name:
Matrix metalloproteinase-14 (MMP-14) ;
Alternative:
MT-MMP ;MMP-X1 ;Membrane-type-1 matrix metalloproteinase (MT1-MMP;MT1MMP) ;Membrane-type matrix metalloproteinase 1 (MT-MMP 1;MTMMP1) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Endopeptidase that degrades various components of the extracellular matrix, such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Extracellular side
Melanosome
Protein Attributes:
50:
MSPAPRPSRS | LLLPLLTLGT | ALASLGWAQG | SNFSPEAWLQ | QYGYLPPGDL |
100:
RTHTQRSPQS | LSAAIAAMQK | FYGLQVTGKA | DLATMMAMRR | PRCGVPDKFG |
150:
TEIKANVRRK | RYAIQGLKWQ | HNEITFCIQN | YTPKVGEYAT | FEAIRKAFRV |
200:
WESATPLRFR | EVPYAYIREG | HEKQADIMIL | FAEGFHGDST | PFDGEGGFLA |
250:
HAYFPGPNIG | GDTHFDSAEP | WTVQNEDLNG | NDIFLVAVHE | LGHALGLEHS |
300:
NDPSAIMAPF | YQWMDTENFV | LPDDDRRGIQ | QLYGSKSGSP | TKMPPQPRTT |
350:
SRPSVPDKPK | NPAYGPNICD | GNFDTVAMLR | GEMFVFKERW | FWRVRNNQVM |
400:
DGYPMPIGQF | WRGLPASINT | AYERKDGKFV | FFKGDKHWVF | DEASLEPGYP |
450:
KHIKELGRGL | PTDKIDAALF | WMPNGKTYFF | RGNKYYRFNE | EFRAVDSEYP |
500:
KNIKVWEGIP | ESPRGSFMGS | DEVFTYFYKG | NKYWKFNNQK | LKVEPGYPKS |
550:
ALRDWMGCPS | GGRPDEGTEE | ETEVIIIEVD | EEGSGAVSAA | AVVLPVLLLL |
582:
LVLAVGLAVF | FFRRHGTPKR | LLYCQRSLLD | KV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Rat
Rabbit
Bovine
Mouse
ELISA Kit for Mouse MMP-14
ELISA Kit for Mouse MMP-14
ELISA Kit for Mouse MMP-14
ELISA Kit for Mouse MMP-14
ELISA Kit for Mouse MMP-14
ELISA Kit for Mouse MMP-14
CLIA Kit for Mouse MMP-14
CLIA Kit for Mouse MMP-14
CLIA Kit for Mouse MMP-14
CLIA Kit for Mouse MMP-14
CLIA Kit for Mouse MMP-14
CLIA Kit for Mouse MMP-14
Polyclonal Antibody for Mouse MMP-14
Polyclonal Antibody for Mouse MMP-14
Polyclonal Antibody for Mouse MMP-14
Polyclonal Antibody for Mouse MMP-14
Polyclonal Antibody for Mouse MMP-14
Polyclonal Antibody for Mouse MMP-14
Monoclonal Antibody for Mouse MMP-14
Monoclonal Antibody for Mouse MMP-14
Monoclonal Antibody for Mouse MMP-14
Monoclonal Antibody for Mouse MMP-14
Monoclonal Antibody for Mouse MMP-14
Monoclonal Antibody for Mouse MMP-14
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
Odaka A.
Submitted (1999-12) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
129/Sv .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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CD-1 .
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Kidney .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
FVB/N .
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
strain :
NOD .
tissue :
Bone marrow .
tissue :
Eye .
tissue :
Spinal cord .
tissue :
Thymus .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION