Protein name:
Matrix metalloproteinase-16 (MMP-16) ;
Alternative:
Membrane-type-3 matrix metalloproteinase (MT3-MMP;MT3MMP) ;Membrane-type matrix metalloproteinase 3 (MT-MMP 3;MTMMP3) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with CSPG4 through CSPG4 chondroitin sulfate glycosaminoglycan.
Function:
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. The short isoform efficiently converts progelatinase A to the intermediate form but not to the mature one. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Subcellular Location:
Isoform Short
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MILLAFSSGR | RLDFVHRSGV | FFFQTLLWIL | CATVCGTEQY | FNVEVWLQKY |
100:
GYLPPTDPRM | SVLRSAETMQ | SALAAMQQFY | GINMTGKVDR | NTIDWMKKPR |
150:
CGVPDQTRGS | SKFNIRRKRY | ALTGQKWQHK | HITYSIKNVT | PKVGDPETRR |
200:
AIRRAFDVWQ | NVTPLTFEEV | PYSELENGKR | DVDITIIFAS | GFHGDRSPFD |
250:
GEGGFLAHAY | FPGPGIGGDT | HFDSDEPWTL | GNPNHDGNDL | FLVAVHELGH |
300:
ALGLEHSNDP | TAIMAPFYQY | METDNFKLPN | DDLQGIQKIY | GPPDKIPPPT |
350:
RPLPTVPPHR | SVPPADPRKN | DRPKPPRPPT | GRPSYPGAKP | NICDGNFNTL |
400:
AILRREMFVF | KDQWFWRVRN | NRVMDGYPMQ | ITYFWRGLPP | SIDAVYENSD |
450:
GNFVFFKGNK | YWVFKDTTLQ | PGYPHDLITL | GNGIPPHGID | SAIWWEDVGK |
500:
TYFFKGDRYW | RYSEEMKTMD | PGYPKPITIW | KGIPESPQGA | FVHKENGFTY |
550:
FYKGKEYWKF | NNQILKVEPG | YPRSILKDFM | GCDGPTDRDK | EGLSPPDDVD |
600:
IVIKLDNTAS | TVKAIAIVIP | CILALCLLVL | VYTVFQFKRK | GTPRHILYCK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Polyclonal Antibody for Rat MMP-16
Polyclonal Antibody for Rat MMP-16
Polyclonal Antibody for Rat MMP-16
Monoclonal Antibody for Rat MMP-16
Monoclonal Antibody for Rat MMP-16
Monoclonal Antibody for Rat MMP-16
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING
tissue :
Smooth muscle .