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Index > Protein center > MMP3(Gene name) > Rabbit
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  • MMP3 (Gene name),
  • Stromelysin-1 (Protein name ),  MMP3_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (2)
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  • Gene name:
    MMP3;
    Protein name:
    Stromelysin-1(SL-1);
    Alternative:
    Transin-1;Matrix metalloproteinase-3(MMP-3);
    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    478
    Sequence:
    50:
    MKTLPTLLLL | CVALCSAYPL | DGASRDADTT | NMDLLQQYLE | NYYNLEKDVK | 
    100:
    QFVKRKDSSP | VVKKIQEMQK | FLGLEVTGKL | DSNTLEVIRK | PRCGVPDVGH | 
    150:
    FSTFPGTPKW | TKTHLTYRIV | NYTPDLPRDA | VDAAIEKALK | VWEEVTPLTF | 
    200:
    SRKYEGEADI | MISFGVREHG | DFIPFDGPGN | VLAHAYAPGP | GINGDAHFDD | 
    250:
    DEQWTKDTTG | TNLFLVAAHE | LGHSLGLFHS | ANPEALMYPV | YNAFTDLARF | 
    300:
    RLSQDDVDGI | QSLYGPAPAS | PDNSGVPMEP | VPPGSGTPVM | CDPDLSFDAI | 
    350:
    STLRGEILFF | KDRYFWRKSL | RILEPEFHLI | SSFWPSLPSA | VDAAYEVISR | 
    400:
    DTVFIFKGTQ | FWAIRGNEVQ | AGYPRSIHTL | GFPSTIRKID | AAISDKERKK | 
    450:
    TYFFVEDKYW | RFDEKRQSLE | PGFPRHIAED | FPGINPKIDA | VFEAFGFFYF | 
    478:
    FSGSSQSEFD | PNAKKVTHVL | KSNSWFQC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rabbit SL-1
    Cat.:
    E0101h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rabbit SL-1
    Cat.:
    E0101m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rabbit SL-1
    Cat.:
    E0101r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rabbit SL-1
    MSDS:
    Please sign in first.
    ELISA Kit for Rabbit SL-1
    Cat.:
    E0101d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rabbit SL-1
    Cat.:
    U0101d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rabbit SL-1
    MSDS:
    Please sign in first.
    CLIA Kit for Rabbit SL-1
    Cat.:
    U0101r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rabbit SL-1
    Cat.:
    U0101h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rabbit SL-1
    Cat.:
    U0101m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Rabbit SL-1
    Cat.:
    P0101Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rabbit SL-1
    Polyclonal Antibody for Rabbit SL-1
    Cat.:
    P0101Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rabbit SL-1
    Polyclonal Antibody for Rabbit SL-1
    Cat.:
    P0101Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rabbit SL-1
    Monoclonal Antibody for Rabbit SL-1
    Monoclonal Antibody for Rabbit SL-1
    Monoclonal Antibody for Rabbit SL-1
    Monoclonal Antibody for Rabbit SL-1
    Protein for Rabbit SL-1
    Protein for Rabbit SL-1
    Protein for Rabbit SL-1
    Protein for Rabbit SL-1
    Protein for Rabbit SL-1

    R&D Technical Data

    s

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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤3.7%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤6.3%

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    Recovery

    Recovery was determined by spiking various levels of MMP3 into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    96-103

    Plasma

    98

    97-105

     

     

     

     

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    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of MMP3 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-99%

    93-100%

    95-102%

    98-106%

    EDTA plasma(n=5)

    96-102%

    100-104%

    96-103%

    97-108%

    heparin plasma(n=5)

    98-105%

     

    102-109%

    97-100%

    89-96%

     

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    References
    1. 1.
      "Cloning of a complementary DNA for rabbit proactivator. A metalloproteinase that activates synovial cell collagenase, shares homology with stromelysin and transin, and is coordinately regulated with collagenase."
      Fini M.E. , Karmilowicz M.J. , Ruby P.L. , Beeman A.M. , Borges K.A. , Brinckerhoff C.E.
      Arthritis Rheum.30:1254-1264(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Comparison of human stromelysin and collagenase by cloning and sequence analysis."
      Whitham S.E. , Murphy G. , Angel P. , Rahmsdorf H.J. , Smith B. , Lyons A. , Harris T.J.R. , Reynolds J.J. , Herrlich P. , Docherty A.J.P.
      Biochem. J.240:913-916(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-167
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