MMP8 ELISA Kit for Human(Homo sapiens) | EIAab.comMMP8 ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > MMP8(Gene name) > Human

MMP8 (Gene name),

Neutrophil collagenase (Protein name ), MMP8_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

MMP8(CLG1);

Protein name:

Neutrophil collagenase;

Alternative:

PMNL collagenase(PMNL-CL);Matrix metalloproteinase-8(MMP-8);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Can degrade fibrillar type I, II, and III collagens.

Subcellular Location:

Cytoplasmic granule Secreted extracellular space extracellular matrix Stored in intracellular granules.

Protein Attributes:

Sequence length:

467

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

467:

RVTRVARGNK | WLNCRYG

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

STRING:

9606.ENSP00000236826

Pfam:

PF00045

SMR:

P22894

MIM:

120355

KEGG:

hsa:4317

String:

P22894

UniGene:

Hs.161839

Uniprot:

P22894

FOR

ELISA Kit for Human Neutrophil collagenase

Cat.:

E0103h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human Neutrophil collagenase

Cat.:

E0103m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human Neutrophil collagenase

Cat.:

E0103r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Neutrophil collagenase

Cat.:

U0103h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Neutrophil collagenase

Cat.:

U0103r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Neutrophil collagenase

Cat.:

U0103m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human Neutrophil collagenase

Cat.:

P0103Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Neutrophil collagenase

Cat.:

P0103Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Neutrophil collagenase

Cat.:

P0103Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Neutrophil collagenase

Protein for Human Neutrophil collagenase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases."
Hasty K.A. , Pourmotabbed T.F. , Goldberg G.I. , Thompson J.P. , Spinella D.G. , Stevens R.M. , Mainardi C.L.
J. Biol. Chem.265:11421-11424(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 314-337; 347-363 AND 424-441
tissue: Neutrophil.
2.

NIEHS SNPs program
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS CYS-3; ILE-32; GLU-87; GLU-154; VAL-193; TYR-246; ALA-436 AND THR-460
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
4.

"Characterization and activation of procollagenase from human polymorphonuclear leucocytes. N-terminal sequence determination of the proenzyme and various proteolytically activated forms."
Knaeuper V. , Kraemer S. , Reinke H. , Tschesche H.
Eur. J. Biochem.189:295-300(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-140;VARIANT ILE-32
tissue: Neutrophil.
5.

"Mercurial activation of human polymorphonuclear leucocyte procollagenase."
Blaeser J. , Knaeuper V. , Osthues A. , Reinke H. , Tschesche H.
Eur. J. Biochem.202:1223-1230(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-103
tissue: Neutrophil.
6.

"Characterization of 58-kilodalton human neutrophil collagenase: comparison with human fibroblast collagenase."
Mallya S.K. , Mookthiar K.A. , Gao Y. , Brew K. , Dioszegi M. , Birkedal-Hansen H. , van Wart H.E.
Biochemistry29:10628-10634(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 85-120;CHARACTERIZATION
tissue: Neutrophil.
7.

"Partial amino acid sequence of human PMN leukocyte procollagenase."
Knaeuper V. , Kraemer S. , Reinke H. , Tschesche H.
Biol. Chem. Hoppe-Seyler371:295-304(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
8.

Knaeuper V. , Kraemer S. , Reinke H. , Tschesche H.
Biol. Chem. Hoppe-Seyler371:733-733(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
9.

"Formation of a covalent Hg-Cys-bond during mercurial activation of PMNL procollagenase gives evidence of a cysteine-switch mechanism."
Blaeser J. , Triebel S. , Reinke H. , Tschesche H.
FEBS Lett.313:59-61(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CYSTEINE-SWITCH MECHANISM
tissue: Neutrophil.
10.

"The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity."
Bode W. , Reinemer P. , Huber R. , Klein T. , Schnierer S. , Tschesche H.
EMBO J.13:1263-1269(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 100-262
11.

"Structural implications for the role of the N-terminus in the 'superactivation' of collagenases. A crystallographic study."
Reinemer P. , Grams F. , Huber R. , Kleine T. , Schnierer S. , Piper M. , Tschesche H. , Bode W.
FEBS Lett.338:227-233(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 100-262
12.

"Structure of human neutrophil collagenase reveals large S1' specificity pocket."
Stams T. , Spurlino J.C. , Smith D.L. , Wahl R.C. , Ho T.F. , Qoronfleh M.W. , Banks T.M. , Rubin B.
Nat. Struct. Biol.1:119-123(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 100-262
13.

"1.8-A crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile."
Betz M. , Huxley P. , Davies S.J. , Mushtaq Y. , Pieper M. , Tschesche H. , Bode W. , Gomis-Rueth F.-X.
Eur. J. Biochem.247:356-363(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.81 ANGSTROMS) OF 100-262
14.

"Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data."
Brandstetter H. , Engh R.A. , von Roedern E.G. , Moroder L. , Huber R. , Bode W. , Grams F.
Protein Sci.7:1303-1309(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 105-262

Product Feedback Wall

* Email:
*Comments: