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Index > Protein center > ALDH6A1(Gene name) > Human
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  • ALDH6A1 (Gene name),
  • Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (Protein name ),  MMSA_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ALDH6A1(MMSDH);
    Protein name:
    Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial(MMSDH;Malonate-semialdehyde dehydrogenase [acylating]);
    Alternative:
    Aldehyde dehydrogenase family 6 member A1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
    Subcellular Location:
    Mitochondrion
    Protein Attributes:
    Sequence length:
    535
    Sequence:
    50:
    MAALLAAAAV | RARILQVSSK | VKSSPTWYSA | SSFSSSVPTV | KLFIGGKFVE | 
    100:
    SKSDKWIDIH | NPATNEVIGR | VPQATKAEMD | AAIASCKRAF | PAWADTSVLS | 
    150:
    RQQVLLRYQQ | LIKENLKEIA | KLITLEQGKT | LADAEGDVFR | GLQVVEHACS | 
    200:
    VTSLMMGETM | PSITKDMDLY | SYRLPLGVCA | GIAPFNFPAM | IPLWMFPMAM | 
    250:
    VCGNTFLMKP | SERVPGATML | LAKLLQDSGA | PDGTLNIIHG | QHEAVNFICD | 
    300:
    HPDIKAISFV | GSNKAGEYIF | ERGSRHGKRV | QANMGAKNHG | VVMPDANKEN | 
    350:
    TLNQLVGAAF | GAAGQRCMAL | STAVLVGEAK | KWLPELVEHA | KNLRVNAGDQ | 
    400:
    PGADLGPLIT | PQAKERVCNL | IDSGTKEGAS | ILLDGRKIKV | KGYENGNFVG | 
    450:
    PTIISNVKPN | MTCYKEEIFG | PVLVVLETET | LDEAIQIVNN | NPYGNGTAIF | 
    500:
    TTNGATARKY | AHLVDVGQVG | VNVPIPVPLP | MFSFTGSRSS | FRGDTNFYGK | 
    535:
    QGIQFYTQLK | TITSQWKEED | ATLSSPAVVM | PTMGR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    UniGene:
    SMR:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human MMSDH
    ELISA Kit for Human MMSDH
    ELISA Kit for Human MMSDH
    ELISA Kit for Human MMSDH
    CLIA Kit for Human MMSDH
    CLIA Kit for Human MMSDH
    CLIA Kit for Human MMSDH
    CLIA Kit for Human MMSDH
    Polyclonal Antibody for Human MMSDH
    Polyclonal Antibody for Human MMSDH
    Polyclonal Antibody for Human MMSDH
    Polyclonal Antibody for Human MMSDH
    Monoclonal Antibody for Human MMSDH
    Monoclonal Antibody for Human MMSDH
    Monoclonal Antibody for Human MMSDH
    Monoclonal Antibody for Human MMSDH
    Protein for Human MMSDH
    Protein for Human MMSDH
    Protein for Human MMSDH
    Protein for Human MMSDH

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular characterization of methylmalonate semialdehyde dehydrogenase deficiency."
      Chambliss K.L. , Gray R.G.F. , Rylance G. , Pollitt R.J. , Gibson K.M.
      J. Inherit. Metab. Dis.23:497-504(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MMSDHD ARG-446
      tissue: Liver.
      tissue: Lymphocyte.
    2. 2.
      "Molecular basis of human MMSDH deficiency: gene organization and mutation analysis."
      Ding J.H. , Yang B.Z. , Wilkinson J. , Roe C.R.
      Submitted (1999-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Skin.
    3. 3.
      "The structure and organization of the methylmalonic semialdehyde dehydrogenase (MMSDH) gene."
      Ding J.H. , Yang B.Z. , Wilkinson J.K. , Roe C.R.
      Submitted (1999-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Amygdala.
    5. 5.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
      tissue: Muscle.
    8. 8.
      "CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distribution."
      Kedishvili N.Y. , Popov K.M. , Rougraff P.M. , Zhao Y. , Crabb D.W. , Harris R.A.
      J. Biol. Chem.267:19724-19729(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 106-535 (ISOFORM 1)
      tissue: Liver.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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