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Index > Protein center > MNDA(Gene name) > Human
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  • MNDA (Gene name),
  • Myeloid cell nuclear differentiation antigen (Protein name ),  MNDA_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    MNDA;
    Protein name:
    Myeloid cell nuclear differentiation antigen;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Participates in a ternary complex with YY1 and the YY1 target DNA element. Binds nucleolin and nucleophosmin/NPM/B23.
    Function:
    May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
    Subcellular Location:
    Nucleus Cytoplasm Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin.
    Protein Attributes:
    Sequence length:
    407
    Sequence:
    50:
    MVNEYKKILL | LKGFELMDDY | HFTSIKSLLA | YDLGLTTKMQ | EEYNRIKITD | 
    100:
    LMEKKFQGVA | CLDKLIELAK | DMPSLKNLVN | NLRKEKSKVA | KKIKTQEKAP | 
    150:
    VKKINQEEVG | LAAPAPTARN | KLTSEARGRI | PVAQKRKTPN | KEKTEAKRNK | 
    200:
    VSQEQSKPPG | PSGASTSAAV | DHPPLPQTSS | STPSNTSFTP | NQETQAQRQV | 
    250:
    DARRNVPQND | PVTVVVLKAT | APFKYESPEN | GKSTMFHATV | ASKTQYFHVK | 
    300:
    VFDINLKEKF | VRKKVITISD | YSECKGVMEI | KEASSVSDFN | QNFEVPNRII | 
    350:
    EIANKTPKIS | QLYKQASGTM | VYGLFMLQKK | SVHKKNTIYE | IQDNTGSMDV | 
    400:
    VGSGKWHNIK | CEKGDKLRLF | CLQLRTVDRK | LKLVCGSHSF | IKVIKAKKNK | 
    407:
    EGPMNVN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    MIM:
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Myeloid cell nuclear differentiation antigen
    Cat.:
    E1775h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Myeloid cell nuclear differentiation antigen
    Cat.:
    U1775h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Myeloid cell nuclear differentiation antigen
    Cat.:
    P1775Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Myeloid cell nuclear differentiation antigen
    Protein for Human Myeloid cell nuclear differentiation antigen

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Cloning and expression of the human myeloid cell nuclear differentiation antigen: regulation by interferon alpha."
      Briggs J.A. , Burrus G.R. , Stickney B.D. , Briggs R.C.
      J. Cell. Biochem.49:82-92(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pancreas.
    3. 3.
      "Characterization of the human myeloid cell nuclear differentiation antigen: relationship to interferon-inducible proteins."
      Burrus G.R. , Briggs J.A. , Briggs R.C.
      J. Cell. Biochem.48:190-202(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;CHARACTERIZATION
    4. 4.
      "The human myeloid cell nuclear differentiation antigen gene is one of at least two related interferon-inducible genes located on chromosome 1q that are expressed specifically in hematopoietic cells."
      Briggs R.C. , Briggs J.A. , Ozer J. , Sealy L. , Dworkin L.L. , Kingsmore S.F. , Seldin M.F. , Kaur G.P. , Athwal R.S. , Dessypris E.N.
      Blood83:2153-2162(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
    5. 5.
      "Interferon alpha selectively affects expression of the human myeloid cell nuclear differentiation antigen in late stage cells in the monocytic but not the granulocytic lineage."
      Briggs R. , Dworkin L. , Briggs J. , Dessypris E. , Stein J. , Stein G. , Lian J.
      J. Cell. Biochem.54:198-206(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY OF ALPHA-INTERFERON INDUCTION
    6. 6.
      "The closely linked genes encoding the myeloid nuclear differentiation antigen (MNDA) and IFI16 exhibit contrasting haemopoietic expression."
      Dawson M.J. , Trapani J.A. , Briggs R.C. , Nicholl J.K. , Sutherland G.R. , Baker E.
      Immunogenetics41:40-43(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL LOCATION;TISSUE SPECIFIC INDUCTION
    7. 7.
      "Human hematopoietic cell specific nuclear protein MNDA interacts with the multifunctional transcription factor YY1 and stimulates YY1 DNA binding."
      Xie J. , Briggs J.A. , Briggs R.C.
      J. Cell. Biochem.70:489-506(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION
    8. 8.
      "Solution structure of the pyrin (PAAD-DAPIN) domain in human myeloid cell nuclear differentiation antigen."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2006-06) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-90
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