Myeloid cell nuclear differentiation antigen (Protein name
), MNDA_HUMAN from NCBI database.
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Gene name:
MNDA;
Protein name:
Myeloid cell nuclear differentiation antigen;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Participates in a ternary complex with YY1 and the YY1 target DNA element. Binds nucleolin and nucleophosmin/NPM/B23.
Function:
May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
Subcellular Location:
Nucleus
Cytoplasm
Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin.
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Cited for: TISSUE SPECIFICITY OF ALPHA-INTERFERON INDUCTION
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Cited for: INTERACTION
8.
"Solution structure of the pyrin (PAAD-DAPIN) domain in human myeloid cell nuclear differentiation antigen." RIKEN structural genomics initiative (RSGI)
Submitted (2006-06) to the PDB data bank
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Cited for: STRUCTURE BY NMR OF 1-90