Slc16a7 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comSlc16a7 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Slc16a7(Gene name) > Rat

Slc16a7 (Gene name),

Monocarboxylate transporter 2 (Protein name ), MOT2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Slc16a7(Mct2);

Protein name:

Monocarboxylate transporter 2(MCT 2);

Alternative:

Solute carrier family 16 member 7;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with GRID2IP.

Function:

Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

489

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

489:

ASQASKEMEA | LSRSKQDDVT | VKVSNTHNPP | SDRDKESSI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.10524

Pfam:

PF07690

String:

Q63344

Uniprot:

Q63344

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ELISA Kit for Rat MCT 2

Cat.:

E12727r

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Packing:

96T

ELISA Kit for Rat MCT 2

Cat.:

E12727h

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96T

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ELISA Kit for Rat MCT 2

Cat.:

E12727m

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96T

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CLIA Kit for Rat MCT 2

Cat.:

U12727m

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96T

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CLIA Kit for Rat MCT 2

Cat.:

U12727h

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96T

CLIA Kit for Rat MCT 2

Cat.:

U12727r

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96T

Polyclonal Antibody for Rat MCT 2

Cat.:

P12727Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MCT 2

Cat.:

P12727Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat MCT 2

Cat.:

P12727Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat MCT 2

Protein for Rat MCT 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤5.1%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.9%

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤3.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.7%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery was determined by spiking various levels of MOT2 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	99	94-105
Plasma	98	93-106

Recovery was determined by spiking various levels of ACE into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	99	91-103
Plasma	98	93-106

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of MOT2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	93-105%	96-101%	95-104%	92-108%
EDTA plasma(n=5)	89-107%	93-105%	90-104%	90-106%
heparin plasma(n=5)	91-104%	94-102%	95-103%	92-103%

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-105%	90-101%	95-105%	92-109%
EDTA plasma(n=5)	89-95%	93105%	89-94%	90-106%
heparin plasma(n=5)	93-104%	94-110%	101-111%	91-110%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulation."
Jackson V.N. , Price N.T. , Carpenter L. , Halestrap A.P.
Biochem. J.324:447-453(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION
strain: Sprague-Dawley.
tissue: Testis.
2.

"Expression of the monocarboxylate transporter MCT2 by rat brain glia."
Gerhart D.Z. , Enerson B.E. , Zhdankina O.Y. , Leino R.L. , Drewes L.R.
Glia22:272-281(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain: Wistar.
tissue: Brain.
3.

"Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70)."
Wilson M.C. , Meredith D. , Fox J.E. , Manoharan C. , Davies A.J. , Halestrap A.P.
J. Biol. Chem.280:27213-27221(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EMB;SUBCELLULAR LOCATION
4.

"The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein."
Ovens M.J. , Manoharan C. , Wilson M.C. , Murray C.M. , Halestrap A.P.
Biochem. J.431:217-225(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EMB;SUBCELLULAR LOCATION;FUNCTION

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