Gene name:
Cdc25a (Cdc25m3) ;
Protein name:
M-phase inducer phosphatase 1 ;
Alternative:
Dual specificity phosphatase Cdc25A ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with CCNB1/cyclin B1. Interacts with YWHAE/14-3-3 epsilon when phosphorylated. Interacts with CUL1 specifically when CUL1 is neddylated and active. Interacts with BTRC/BTRCP1 and FBXW11/BTRCP2. Interactions with CUL1, BTRC and FBXW11 are enhanced upon DNA damage.
Function:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
Subcellular Location:
N/A
Protein Attributes:
50:
MELGPSPPPR | RLFFACSPTP | ASQPTGKMLF | GASAAGGLSP | VTNLTVTMDQ |
100:
LEGLGSDCEK | MEVRNNSSLQ | RMGSSESTDS | GFCLDSPGPL | DSKENLEISL |
150:
TRINSLPQKL | LGCSPALKRS | HSDSLDQDTF | HLIDQDKNKE | NEAFEPKKQY |
200:
DLHLSSHLQE | SKDLYTQRQN | SAQLGMLSSN | ESESGNFSPL | FTPQSPVKAT |
250:
LSDEDDGFID | LLDGENLKND | EETPTSMVSL | WTAPLVMRRP | ANLADRLRGL |
300:
FDSPSPCGSS | TRAVLKRADR | SHEEPPRGTK | RRKSVPSPVK | AKADVPEPAQ |
350:
LPSQSLSLMS | SPKGTIENIL | DSDPRDLIGD | FSKGYLFNTV | SGKHQDLKYI |
400:
SPEIMASVLN | GKFASLIKEF | VIIDCRYPYE | YEGGHIKGAV | NLHMEEEVED |
450:
FLLKNPIVPT | DGKRVIVVFH | CEFSSERGPR | MCRYVRERDR | LGNEYPKLHY |
500:
PELYVLKGGY | KEFFLKCQSH | CEPPSYRPMH | HEDFKEDLKK | FRTKSRTWAG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Rat
Mouse
ELISA Kit for Mouse M-phase inducer phosphatase 1
ELISA Kit for Mouse M-phase inducer phosphatase 1
ELISA Kit for Mouse M-phase inducer phosphatase 1
ELISA Kit for Mouse M-phase inducer phosphatase 1
CLIA Kit for Mouse M-phase inducer phosphatase 1
CLIA Kit for Mouse M-phase inducer phosphatase 1
CLIA Kit for Mouse M-phase inducer phosphatase 1
CLIA Kit for Mouse M-phase inducer phosphatase 1
Polyclonal Antibody for Mouse M-phase inducer phosphatase 1
Polyclonal Antibody for Mouse M-phase inducer phosphatase 1
Polyclonal Antibody for Mouse M-phase inducer phosphatase 1
Polyclonal Antibody for Mouse M-phase inducer phosphatase 1
Monoclonal Antibody for Mouse M-phase inducer phosphatase 1
Monoclonal Antibody for Mouse M-phase inducer phosphatase 1
Monoclonal Antibody for Mouse M-phase inducer phosphatase 1
Monoclonal Antibody for Mouse M-phase inducer phosphatase 1
Protein for Mouse M-phase inducer phosphatase 1
Protein for Mouse M-phase inducer phosphatase 1
Protein for Mouse M-phase inducer phosphatase 1
Protein for Mouse M-phase inducer phosphatase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
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Goodstadt L.
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Hillier L.W.
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Zody M.C.
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Goldstein S.
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She X.
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DiCuccio M.
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Hlavina W.
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Kapustin Y.
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Meric P.
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Maglott D.
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Birtle Z.
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Marques A.C.
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Graves T.
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Zhou S.
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Teague B.
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Potamousis K.
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Churas C.
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Place M.
,
Herschleb J.
,
Runnheim R.
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Forrest D.
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Amos-Landgraf J.
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Schwartz D.C.
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Cheng Z.
,
Lindblad-Toh K.
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Eichler E.E.
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Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .