Mpp5 ELISA Kit for Mouse(Mus musculus) | EIAab.comMpp5 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Mpp5(Gene name) > Mouse

Mpp5 (Gene name),

MAGUK p55 subfamily member 5 (Protein name ), MPP5_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Mpp5(Pals1);

Protein name:

MAGUK p55 subfamily member 5;

Alternative:

Protein associated with Lin-7 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterodimer with MPP1. Interacts with MPP7. Forms a complex with CRB1 and MPP4. Component of a complex whose core is composed of ARHGAP17, AMOT, MPP5/PALS1, INADL/PATJ and PARD3/PAR3 (By similarity). Interacts with CRB3, EZR, INADL, LIN7C, MPDZ, PARD6B and SC6A1.

Function:

May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton.

Subcellular Location:

Cell membrane Peripheral membrane protein Endomembrane system Peripheral membrane protein Cell junction tight junction Localized to the tight junctions of epithelial cells and a subset of intracellular vesicles. Localized to the Purkinje cell body and axon. Localized to apical membrane domains of the outer limiting membrane junctions in the retina. Colocalizes with MPP1 in the retina at the outer limiting membrane (OLM).

Protein Attributes:

Sequence length:

675

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

675:

AYQELLRLIN | KLDTEPQWVP | STWLR

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

Q9JLB2

Pfam:

PF00625

String:

Q9JLB2

UniGene:

Mm.425777

KEGG:

mmu:56217

Uniprot:

Q9JLB2

FOR

ELISA Kit for Mouse MAGUK p55 subfamily member 5

CLIA Kit for Mouse MAGUK p55 subfamily member 5

Polyclonal Antibody for Mouse MAGUK p55 subfamily member 5

Monoclonal Antibody for Mouse MAGUK p55 subfamily member 5

Protein for Mouse MAGUK p55 subfamily member 5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and characterization of Pals, proteins associated with mLin-7."
Kamberov E. , Makarova O. , Roh M. , Liu A. , Karnak D. , Straight S. , Margolis B.
J. Biol. Chem.275:11425-11431(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];MUTAGENESIS OF GLU-207; LEU-208; LEU-212; HIS-216; LEU-221; HIS-224; ASP-225 AND VAL-227;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;INTERACTION WITH LIN7C
tissue: Embryo.
2.

"The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost."
Roh M.H. , Makarova O. , Liu C.-J. , Shin K. , Lee S. , Laurinec S. , Goyal M. , Wiggins R. , Margolis B.
J. Cell Biol.157:161-172(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH INADL;DOMAIN;SUBCELLULAR LOCATION;MUTAGENESIS OF LEU-150 AND VAL-154
3.

"Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1)."
Makarova O. , Roh M.H. , Liu C.-J. , Laurinec S. , Margolis B.
Gene302:21-29(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CRB3
4.

"Direct interaction of two polarity complexes implicated in epithelial tight junction assembly."
Hurd T.W. , Gao L. , Roh M.H. , Macara I.G. , Margolis B.
Nat. Cell Biol.5:137-142(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PARD6B
5.

"Tight junction protein Par6 interacts with an evolutionarily conserved region in the amino terminus of PALS1/stardust."
Wang Q. , Hurd T.W. , Margolis B.
J. Biol. Chem.279:30715-30721(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF HIS-32; ARG-33; GLU-34; ALA-36; VAL-37; ASP-38; CYS-39 AND PRO-40;SUBCELLULAR LOCATION;INTERACTION WITH PARD6B
6.

"Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure."
van de Pavert S.A. , Kantardzhieva A. , Malysheva A. , Meuleman J. , Versteeg I. , Levelt C. , Klooster J. , Geiger S. , Seeliger M.W. , Rashbass P. , Le Bivic A. , Wijnholds J.
J. Cell Sci.117:4169-4177(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MPDZ
7.

"The GABA transporter GAT1 and the MAGUK protein Pals1: interaction, uptake modulation, and coexpression in the brain."
McHugh E.M. , Zhu W. , Milgram S. , Mager S.
Mol. Cell. Neurosci.26:406-417(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SC6A1;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;DOMAIN
8.

"PALS1 specifies the localization of Ezrin to the apical membrane of gastric parietal cells."
Cao X. , Ding X. , Guo Z. , Zhou R. , Wang F. , Long F. , Wu F. , Bi F. , Wang Q. , Fan D. , Forte J.G. , Teng M. , Yao X.
J. Biol. Chem.280:13584-13592(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EZR;SUBCELLULAR LOCATION;FUNCTION
9.

"Membrane-associated guanylate kinase proteins MPP4 and MPP5 associate with Veli3 at distinct intercellular junctions of the neurosensory retina."
Stoehr H. , Molday L.L. , Molday R.S. , Weber B.H.F. , Biedermann B. , Reichenbach A. , Kraemer F.
J. Comp. Neurol.481:31-41(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;SUBCELLULAR LOCATION
10.

"Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexes."
Li Y. , Karnak D. , Demeler B. , Margolis B. , Lavie A.
EMBO J.23:2723-2733(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 123-180
11.

"Solution structure of the PDZ domain of PALS1 protein."
RIKEN structural genomics initiative (RSGI)
Submitted (2005-02) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 236-335

Product Feedback Wall

* Email:
*Comments: