Igf2r ELISA Kit for Mouse(Mus musculus) | EIAab.comIgf2r ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Igf2r(Gene name) > Mouse

Igf2r (Gene name),

Cation-independent mannose-6-phosphate receptor (Protein name ), MPRI_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Igf2r;

Protein name:

Cation-independent mannose-6-phosphate receptor(CI Man-6-P receptor;CI-MPR;M6PR);

Alternative:

Insulin-like growth factor 2 receptor;300 kDa mannose 6-phosphate receptor(MPR 300);M6P/IGF2 receptor(M6P/IGF2R);Insulin-like growth factor II receptor(IGF-II receptor);

CD:

CD222;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with DPP4; the interaction is direct. Binds GGA1, GGA2 and GGA3. Binds HA-I and HA-II plasma membrane adapters.

Function:

Acts as a positive regulator of T-cell coactivation, by binding DPP4 (By similarity). Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2.

Subcellular Location:

Lysosome membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

2483

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2483:

ARKGKFRPGQ | RKPTAPAKLV | SFHDDSDEDL | LHI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.26553

Pfam:

PF00878

SMR:

Q07113

String:

Q07113

KEGG:

mmu:16004

Uniprot:

Q07113

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ELISA Kit for Mouse CI Man-6-P receptor

Cat.:

E1629h

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Manual:

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Packing:

96T

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ELISA Kit for Mouse CI Man-6-P receptor

Cat.:

E1629m

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Packing:

96T

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ELISA Kit for Mouse CI Man-6-P receptor

Cat.:

E1629b

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Looking for manual.

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96T

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CLIA Kit for Mouse CI Man-6-P receptor

Cat.:

U1629h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse CI Man-6-P receptor

Cat.:

U1629b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse CI Man-6-P receptor

Cat.:

U1629m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse CI Man-6-P receptor

Cat.:

P1629Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse CI Man-6-P receptor

Cat.:

P1629Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse CI Man-6-P receptor

Protein for Mouse CI Man-6-P receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"The mouse insulin-like growth factor II/cation-independent mannose 6-phosphate (IGF-II/MPR) receptor gene: molecular cloning and genomic organization."
Szebenyi G. , Rotwein P.
Genomics19:120-129(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Cloning and sequencing of cDNAs encoding the full-length mouse mannose 6-phosphate/insulin-like growth factor II receptor."
Ludwig T. , Tenscher K. , Remmler J. , Hoflack B. , Lobel P.
Gene142:311-312(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6 X CBA.
tissue: Liver.
3.

"Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal."
Stoger R. , Kubicka P. , Liu C.G. , Kafri T. , Razin A. , Cedar H. , Barlow D.P.
Cell73:61-71(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-44 AND 93-106
strain: 129.
strain: C57BL/6.
4.

"Control of insulin-like growth factor-II/mannose 6-phosphate receptor gene transcription by proximal promoter elements."
Liu Z. , Mittanck D.W. , Kim S. , Rotwein P.
Mol. Endocrinol.9:1477-1487(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-44
strain: 129/Sv.
5.

"Differential regulation of mannose 6-phosphate receptors and their ligands during the myogenic development of C2 cells."
Szebenyi G. , Rotwein P.
J. Biol. Chem.266:5534-5539(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 435-488
tissue: Liver.
6.

Matzner U.
Submitted (1992-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1625-2045
strain: C57BL/6.
7.

"Mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor. A consensus casein kinase II site followed by 2 leucines near the carboxyl terminus is important for intracellular targeting of lysosomal enzymes."
Chen H.J. , Remmler J. , Delaney J.C. , Messner D.J. , Lobel P.
J. Biol. Chem.268:22338-22346(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2249-2483
strain: C57BL/6 X CBA.
tissue: Liver.
8.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2401 AND SER-2476;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
9.

"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H. , Ye M. , Dong J. , Han G. , Jiang X. , Wu R. , Zou H.
J. Proteome Res.7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2476;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
10.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2471 AND SER-2476;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.

"The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
Gundry R.L. , Raginski K. , Tarasova Y. , Tchernyshyov I. , Bausch-Fluck D. , Elliott S.T. , Boheler K.R. , Van Eyk J.E. , Wollscheid B.
Mol. Cell. Proteomics8:2555-2569(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1532
tissue: Myoblast.
12.

"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2401 AND SER-2476;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
13.

"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-740; ASN-1532 AND ASN-1750

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