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Index > Protein center > Mpzl1(Gene name) > Mouse
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  • Mpzl1 (Gene name),
  • Myelin protein zero-like protein 1 (Protein name ),  MPZL1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mpzl1(Pzr);
    Protein name:
    Myelin protein zero-like protein 1;
    Alternative:
    Protein zero-related;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with phosphorylated PTPN11/SHP-2.
    Function:
    Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 2 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2, may be involved in regulation of integrin-mediated cell motility.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    270
    Sequence:
    50:
    MAEAVGAVAL | IAAPARRRWL | WSVLAAMLGL | LTARISALEV | HTPKEIFVVN | 
    100:
    GTQGKLTCTF | DSPNTTGWLT | TVSWSFQPDG | TDSAVSFFHY | SQGQVYIGDY | 
    150:
    PPFKDRVTWA | GDLDKKDASI | NIENIQAVHN | GTYICDVKNP | PDIVVRPGHI | 
    200:
    RLHVVEIDNL | LVFLVWVVVG | TVTAVVLGLT | LLISLVLVVL | YRRKHSKRDY | 
    250:
    TGCSTSERLS | PVKQAPRKCP | SDTEGLVKSP | PSAGSHQGPV | IYAQLDHSGG | 
    270:
    HHSGKINKSE | SVVYADIRKD | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Myelin protein zero-like protein 1
    ELISA Kit for Mouse Myelin protein zero-like protein 1
    ELISA Kit for Mouse Myelin protein zero-like protein 1
    ELISA Kit for Mouse Myelin protein zero-like protein 1
    CLIA Kit for Mouse Myelin protein zero-like protein 1
    CLIA Kit for Mouse Myelin protein zero-like protein 1
    CLIA Kit for Mouse Myelin protein zero-like protein 1
    CLIA Kit for Mouse Myelin protein zero-like protein 1
    Polyclonal Antibody for Mouse Myelin protein zero-like protein 1
    Polyclonal Antibody for Mouse Myelin protein zero-like protein 1
    Polyclonal Antibody for Mouse Myelin protein zero-like protein 1
    Polyclonal Antibody for Mouse Myelin protein zero-like protein 1
    Monoclonal Antibody for Mouse Myelin protein zero-like protein 1
    Monoclonal Antibody for Mouse Myelin protein zero-like protein 1
    Monoclonal Antibody for Mouse Myelin protein zero-like protein 1
    Monoclonal Antibody for Mouse Myelin protein zero-like protein 1
    Protein for Mouse Myelin protein zero-like protein 1
    Protein for Mouse Myelin protein zero-like protein 1
    Protein for Mouse Myelin protein zero-like protein 1
    Protein for Mouse Myelin protein zero-like protein 1

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Stomach.
    2. 2.
      "The murine ortholog of the SHP-2 binding molecule, PZR, is expressed during mesodermal commitment and accelerates cell migration on fibronectin."
      Roubelakis M.G. , Martin-Rendon E. , Tsaknakis G. , Watt S.M.
      Submitted (2004-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-130
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