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Index > Protein center > Cdc42bpa(Gene name) > Mouse
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  • Cdc42bpa (Gene name),
  • Serine/threonine-protein kinase MRCK alpha (Protein name ),  MRCKA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cdc42bpa(Kiaa0451);
    Protein name:
    Serine/threonine-protein kinase MRCK alpha;
    Alternative:
    CDC42-binding protein kinase alpha;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer and homotetramer via the coiled coil regions. Interacts tightly with GTP-bound but not GDP-bound CDC42.
    Function:
    May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.
    Subcellular Location:
    Cytoplasm Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent.
    Protein Attributes:
    Sequence length:
    1719
    Sequence:
    50:
    MSGEVRLRQL | EQFILDGPAQ | TNGQCFSVET | LLDILICLYD | ECNNSPLRRE | 
    100:
    KNILEYLEWA | KPFTSKVKQM | RLHREDFEIL | KVIGRGAFGE | VAVVKLKNAD | 
    150:
    KVFAMKILNK | WEMLKRAETA | CFREERDVLV | NGDSKWITTL | HYAFQDDNNL | 
    200:
    YLVMDYYVGG | DLLTLLSKFE | DRLPEEMARF | YLAEMVIAID | SVHQLHYVHR | 
    250:
    DIKPDNILMD | MNGHIRLADF | GSCLKLMEDG | TVQSSVAVGT | PDYISPEILQ | 
    300:
    AMEDGKGRYG | PECDWWSLGV | CMYEMLYGET | PFYAESLVET | YGKIMNHKER | 
    350:
    FQFPAQVTDV | SENAKDLIRR | LICSREHRLG | QNGIEDFKKH | PFFSGIDWDN | 
    400:
    IRNCEAPYIP | EVSSPTDTSN | FDVDDDCLKN | SETMPPPTHT | AFSGHHLPFV | 
    450:
    GFTYTSSCVL | SDRSCLRVTA | GPTSLDLDVS | VQRTLDNNLA | TEAYERRIKR | 
    500:
    LEQEKLELTR | KLQESTQTVQ | ALQYSTVDGP | LTASKDLEIK | SLKEEIEKLR | 
    550:
    KQVAEVNHLE | QQLEEANSVR | RELDDAFRQI | KASEKQIKTL | QQEREELNKE | 
    600:
    LVQASERLKN | QSKELKDAHC | QRKLAMQEFM | EINERLTELH | TQKQKLARHV | 
    650:
    RDKEEEVDLV | MQKAESLRQE | LRRAERAKKE | LEVHTEALIA | EASKDKKLRE | 
    700:
    QSEHYSKQLE | NELEGLKQKQ | ISYSPGICSI | EHQQEITKLK | TDLEKKSIFY | 
    750:
    EEEISKREGI | HASEIKNLKK | ELHDSEGQQL | ALNKEILVLK | DKLEKTRRES | 
    800:
    QSEREEFENE | FKQQYEREKV | LLTEENKKLT | SELDKLTSLY | ESLSLRNQHL | 
    850:
    EEEVKDLADK | KESVAHWEAQ | ITEIIQWVSD | EKDARGYLQA | LASKMTEELE | 
    900:
    ALRNSSLGTR | ATDMPWKMRR | FAKLDMSARL | ELQSALDAEI | RAKQAIQEEL | 
    950:
    NKVKASNILT | ECKLKDSEKK | NLELLSEIEQ | LIKDTEELRS | EKGIEHQDSQ | 
    1000:
    HSFLAFLNTP | TDALDQFEIA | DCAPLPAHTP | TLRKKGCPAS | TGFPPKRKTH | 
    1050:
    QFFVKSFTAP | TKCHQCTSLM | VGLIRQGCSC | EVCGFSCHIT | CVNKAPTVCP | 
    1100:
    VPPEQTKGPL | GIDPQKGVGT | AYEGHVRIPK | PAGVKKGWQR | ALAVVCDFKL | 
    1150:
    FLYDIAEGKA | SQPTSVISQV | IDMRDEEFSV | SSVLASDVIH | ASRKDIPCIF | 
    1200:
    RVTASQLSAP | SNKCSILMLA | DSENERSKWV | GVLSELHKIL | KKNKFRDRSV | 
    1250:
    YVPKEAYDST | LPLIKTTQAA | AIIDHERIAL | GNEEGLFVVH | VTKDEIVRVG | 
    1300:
    DNKKIHQIEL | IPSDQLVAVI | SGRNRHVRLF | PMSALDGRET | DFYKLAETKG | 
    1350:
    CQTIAAGKVR | HGALSCLCVA | MKRQVLCYEL | FQSKTRHRKF | KEIQVPCNVQ | 
    1400:
    WMAIFSEHLC | VGFQSGFLRY | PLNGEGGPCN | MLHSNDHTLS | FISHQPMDAL | 
    1450:
    CAVEISNKEY | LLCFNSIGIY | TDCQGRRSRQ | QELMWPANPS | SCCYNAPYLS | 
    1500:
    VYSENAVDIF | DVNSMEWIQT | LPLKKVRPLN | TEGSLNLLGL | ETIRLIYFKN | 
    1550:
    KMAEGDELVV | PETSDNSRKQ | MVRNINNKRR | YSFRVPEEER | MQQRREMLRD | 
    1600:
    PEMRNKLISN | PTNFNHIAHM | GPGDGIQILK | DLPMNPRPQE | SRTVFSGSVS | 
    1650:
    IPSITKSRPE | PGRSMSASSG | LSARSSAQNG | SALKREFSGG | SYNTKRQPMP | 
    1700:
    SPSEGSLSSG | GMDQGSDAPA | RDYDGEDSDS | PRHSTASNSS | NLSSPPSPIS | 
    1719:
    PQKTKSLSLE | STDRGSWDP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Serine/threonine-protein kinase MRCK alpha
    ELISA Kit for Mouse Serine/threonine-protein kinase MRCK alpha
    ELISA Kit for Mouse Serine/threonine-protein kinase MRCK alpha
    CLIA Kit for Mouse Serine/threonine-protein kinase MRCK alpha
    CLIA Kit for Mouse Serine/threonine-protein kinase MRCK alpha
    CLIA Kit for Mouse Serine/threonine-protein kinase MRCK alpha
    Polyclonal Antibody for Mouse Serine/threonine-protein kinase MRCK alpha
    Polyclonal Antibody for Mouse Serine/threonine-protein kinase MRCK alpha
    Polyclonal Antibody for Mouse Serine/threonine-protein kinase MRCK alpha
    Monoclonal Antibody for Mouse Serine/threonine-protein kinase MRCK alpha
    Monoclonal Antibody for Mouse Serine/threonine-protein kinase MRCK alpha
    Monoclonal Antibody for Mouse Serine/threonine-protein kinase MRCK alpha
    Protein for Mouse Serine/threonine-protein kinase MRCK alpha
    Protein for Mouse Serine/threonine-protein kinase MRCK alpha
    Protein for Mouse Serine/threonine-protein kinase MRCK alpha

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1451-1719
      strain: C57BL/6J.
      tissue: Brain.
      tissue: Mammary gland.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-752 (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Spinal cord.
    4. 4.
      "MRCK-alpha interacts with Dexras1."
      Behrend E.N. , Kemppainen R.J.
      Submitted (2002-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 736-1006
    5. 5.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1376-1719
      tissue: Brain.
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