Gene name:
Mettl3 (Mta70) ;
Protein name:
N6-adenosine-methyltransferase 70 kDa subunit (MT-A70) ;
Alternative:
N6-adenosine-methyltransferase 70 kDa subunit (MT-A70) ;Methyltransferase-like protein 3 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation.
Subcellular Location:
Nucleus speckle
Colocalizes with speckles in interphase nuclei. Suggesting that it may be associated with nuclear pre-mRNA splicing components.
Protein Attributes:
50:
MSDTWSSIQA | HKKQLDSLRE | RLQRRRKQDS | GHLDLRNPEA | ALSPTFRSDS |
100:
PVPTAPTSSG | PKPSTTSVAP | ELATDPELEK | KLLHHLSDLA | LTLPTDAVSI |
150:
RLAISTPDAP | ATQDGVESLL | QKFAAQELIE | VKRGLLQDDA | HPTLVTYADH |
200:
SKLSAMMGAV | ADKKGLGEVA | GTIAGQKRRA | EQDLTTVTTF | ASSLASGLAS |
250:
SASEPAKEPA | KKSRKHAASD | VDLEIESLLN | QQSTKEQQSK | KVSQEILELL |
300:
NTTTAKEQSI | VEKFRSRGRA | QVQEFCDYGT | KEECMKASDA | DRPCRKLHFR |
350:
RIINKHTDES | LGDCSFLNTC | FHMDTCKYVH | YEIDACVDSE | SPGSKEHMPS |
400:
QELALTQSVG | GDSSADRLFP | PQWICCDIRY | LDVSILGKFA | VVMADPPWDI |
450:
HMELPYGTLT | DDEMRRLNIP | VLQDDGFLFL | WVTGRAMELG | RECLNLWGYE |
500:
RVDEIIWVKT | NQLQRIIRTG | RTGHWLNHGK | EHCLVGVKGN | PQGFNQGLDC |
550:
DVIVAEVRST | SHKPDEIYGM | IERLSPGTRK | IELFGRPHNV | QPNWITLGNQ |
580:
LDGIHLLDPD | VVARFKQRYP | DGIISKPKNL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse MT-A70
ELISA Kit for Mouse MT-A70
CLIA Kit for Mouse MT-A70
CLIA Kit for Mouse MT-A70
Polyclonal Antibody for Mouse MT-A70
Polyclonal Antibody for Mouse MT-A70
Monoclonal Antibody for Mouse MT-A70
Monoclonal Antibody for Mouse MT-A70
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
strain :
129/Sv .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
strain :
C57BL/6 X DBA/2 .
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Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6J .
tissue :
Stomach .
tissue :
Tongue .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Mammary tumor .
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Cell155:793-806(2013)
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PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;MUTAGENESIS OF 395-ASP--TRP-398
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION;INTERACTION WITH METTL14