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Index > Protein center > Mettl3(Gene name) > Mouse
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  • Mettl3 (Gene name),
  • N6-adenosine-methyltransferase 70 kDa subunit (Protein name ),  MTA70_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mettl3(Mta70);
    Protein name:
    N6-adenosine-methyltransferase 70 kDa subunit(MT-A70);
    Alternative:
    N6-adenosine-methyltransferase 70 kDa subunit(MT-A70);Methyltransferase-like protein 3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation.
    Subcellular Location:
    Nucleus speckle Colocalizes with speckles in interphase nuclei. Suggesting that it may be associated with nuclear pre-mRNA splicing components.
    Protein Attributes:
    Sequence length:
    580
    Sequence:
    50:
    MSDTWSSIQA | HKKQLDSLRE | RLQRRRKQDS | GHLDLRNPEA | ALSPTFRSDS | 
    100:
    PVPTAPTSSG | PKPSTTSVAP | ELATDPELEK | KLLHHLSDLA | LTLPTDAVSI | 
    150:
    RLAISTPDAP | ATQDGVESLL | QKFAAQELIE | VKRGLLQDDA | HPTLVTYADH | 
    200:
    SKLSAMMGAV | ADKKGLGEVA | GTIAGQKRRA | EQDLTTVTTF | ASSLASGLAS | 
    250:
    SASEPAKEPA | KKSRKHAASD | VDLEIESLLN | QQSTKEQQSK | KVSQEILELL | 
    300:
    NTTTAKEQSI | VEKFRSRGRA | QVQEFCDYGT | KEECMKASDA | DRPCRKLHFR | 
    350:
    RIINKHTDES | LGDCSFLNTC | FHMDTCKYVH | YEIDACVDSE | SPGSKEHMPS | 
    400:
    QELALTQSVG | GDSSADRLFP | PQWICCDIRY | LDVSILGKFA | VVMADPPWDI | 
    450:
    HMELPYGTLT | DDEMRRLNIP | VLQDDGFLFL | WVTGRAMELG | RECLNLWGYE | 
    500:
    RVDEIIWVKT | NQLQRIIRTG | RTGHWLNHGK | EHCLVGVKGN | PQGFNQGLDC | 
    550:
    DVIVAEVRST | SHKPDEIYGM | IERLSPGTRK | IELFGRPHNV | QPNWITLGNQ | 
    580:
    LDGIHLLDPD | VVARFKQRYP | DGIISKPKNL | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse MT-A70
    Cat.:
    E13478h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse MT-A70
    Cat.:
    E13478m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse MT-A70
    Cat.:
    U13478h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse MT-A70
    Cat.:
    U13478m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse MT-A70
    Cat.:
    P13478Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse MT-A70
    Cat.:
    P13478Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse MT-A70
    Monoclonal Antibody for Mouse MT-A70
    Protein for Mouse MT-A70
    Protein for Mouse MT-A70

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase."
      Bokar J.A. , Shambaugh M.E. , Polayes D. , Matera A.G. , Rottman F.M.
      RNA3:1233-1247(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
      strain: 129/Sv.
    2. 2.
      "Expression of genes involved in mammalian meiosis during the transition from egg to embryo."
      Hwang S.-Y. , Oh B. , Knowles B.B. , Solter D. , Lee J.-S.
      Mol. Reprod. Dev.59:144-158(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      strain: C57BL/6 X DBA/2.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Stomach.
      tissue: Tongue.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Mammary tumor.
    5. 5.
      "RNA-methylation-dependent RNA processing controls the speed of the circadian clock."
      Fustin J.M. , Doi M. , Yamaguchi Y. , Hida H. , Nishimura S. , Yoshida M. , Isagawa T. , Morioka M.S. , Kakeya H. , Manabe I. , Okamura H.
      Cell155:793-806(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF 395-ASP--TRP-398
    6. 6.
      "N-methyladenosine modification destabilizes developmental regulators in embryonic stem cells."
      Wang Y. , Li Y. , Toth J.I. , Petroski M.D. , Zhang Z. , Zhao J.C.
      Nat. Cell Biol.16:191-198(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION;INTERACTION WITH METTL14
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