Gene name:
MRI1 (UNQ6390/PRO21135;MRDI) ;
Protein name:
Methylthioribose-1-phosphate isomerase (M1Pi;MTR-1-P isomerase) ;
Alternative:
S-methyl-5-thioribose-1-phosphate isomerase ;Mediator of RhoA-dependent invasion ;Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
Subcellular Location:
Nucleus
Cytoplasm
Cell projection
Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
Protein Attributes:
50:
MTLEAIRYSR | GSLQILDQLL | LPKQSRYEAV | GSVHQAWEAI | RAMKVRGAPA |
100:
IALVGCLSLA | VELQAGAGGP | GLAALVAFVR | DKLSFLVTAR | PTAVNMARAA |
150:
RDLADVAARE | AEREGATEEA | VRERVICCTE | DMLEKDLRDN | RSIGDLGARH |
200:
LLERVAPSGG | KVTVLTHCNT | GALATAGYGT | ALGVIRSLHS | LGRLEHAFCT |
250:
ETRPYNQGAR | LTAFELVYEQ | IPATLITDSM | VAAAMAHRGV | SAVVVGADRV |
300:
VANGDTANKV | GTYQLAIVAK | HHGIPFYVAA | PSSSCDLRLE | TGKEIIIEER |
350:
PGQELTDVNG | VRIAAPGIGV | WNPAFDVTPH | DLITGGIITE | LGVFAPEELR |
369:
TALTTTISSR | DGTLDGPQM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Bovine
Polyclonal Antibody for Human M1Pi
Polyclonal Antibody for Human M1Pi
Polyclonal Antibody for Human M1Pi
Polyclonal Antibody for Human M1Pi
Monoclonal Antibody for Human M1Pi
Monoclonal Antibody for Human M1Pi
Monoclonal Antibody for Human M1Pi
Monoclonal Antibody for Human M1Pi
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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Brain .
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