MTRR ELISA Kit for Human(Homo sapiens) | EIAab.comMTRR ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MTRR(Gene name) > Human

MTRR (Gene name),

Methionine synthase reductase (Protein name ), MTRR_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MTRR;

Protein name:

Methionine synthase reductase(MSR);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Involved in the reductive regeneration of cob(I)alamin cofactor required for the maintenance of methionine synthase in a functional state.

Subcellular Location:

Isoform A Cytoplasm

Protein Attributes:

Sequence length:

725

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

725:

VEKLEAMKTL | ATLKEEKRYL | QDIWS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9UBK8

Pfam:

PF00667

KEGG:

hsa:4552

MIM:

236270

UniGene:

Hs.481551

STRING:

9606.ENSP00000264668

SMR:

Q9UBK8

Uniprot:

Q9UBK8

FOR

ELISA Kit for Human MSR

CLIA Kit for Human MSR

Polyclonal Antibody for Human MSR

Monoclonal Antibody for Human MSR

Protein for Human MSR

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning, expression and physical mapping of the human methionine synthase reductase gene."
Leclerc D. , Odievre M.-H. , Wu Q. , Wilson A. , Huizenga J. , Rozen R. , Scherer S.W. , Gravel R.A.
Gene240:75-88(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS A; B AND C);VARIANT LEU-202
2.

"Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria."
Leclerc D. , Wilson A. , Dumas R. , Gafuik C. , Song D. , Watkins D. , Heng H.H.Q. , Rommens J.M. , Scherer S.W. , Rosenblatt D.S. , Gravel R.A.
Proc. Natl. Acad. Sci. U.S.A.95:3059-3064(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS B AND C);VARIANT LEU-202;VARIANT HMAE LEU-603 DEL
3.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS A AND B)
tissue: Lung.
5.

"Restricted role for methionine synthase reductase defined by subcellular localization."
Froese D.S. , Wu X. , Zhang J. , Dumas R. , Schoel W.M. , Amrein M. , Gravel R.A.
Mol. Genet. Metab.94:68-77(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION (ISOFORM A)
6.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-198;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
7.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.

"Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry."
Wolthers K.R. , Lou X. , Toogood H.S. , Leys D. , Scrutton N.S.
Biochemistry46:11833-11844(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 192-725 IN COMPLEX WITH FAD AND NADP;COFACTOR;BIOPHYSICOCHEMICAL PROPERTIES;CATALYTIC ACTIVITY;FUNCTION
9.

"Molecular basis for methionine synthase reductase deficiency in patients belonging to the cblE complementation group of disorders in folate/cobalamin metabolism."
Wilson A. , Leclerc D. , Rosenblatt D.S. , Gravel R.A.
Hum. Mol. Genet.8:2009-2016(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HMAE VAL-81 DEL; MET-83; THR-156; ARG-432; ARG-514 AND ARG-581;VARIANT VAL-360
10.

"A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida."
Wilson A. , Platt R. , Wu Q. , Leclerc D. , Christensen B. , Yang H. , Gravel R.A. , Rozen R.
Mol. Genet. Metab.67:317-323(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION OF VARIANT MET-49 WITH SUSCEPTIBILITY TO FS-NTD
11.

"Maternal genetic effects, exerted by genes involved in homocysteine remethylation, influence the risk of spina bifida."
Doolin M.-T. , Barbaux S. , McDonnell M. , Hoess K. , Whitehead A.S. , Mitchell L.E.
Am. J. Hum. Genet.71:1222-1226(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION OF VARIANT MET-49 WITH SUSCEPTIBILITY TO FS-NTD
12.

"Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association."
O'Leary V.B. , Mills J.L. , Pangilinan F. , Kirke P.N. , Cox C. , Conley M. , Weiler A. , Peng K. , Shane B. , Scott J.M. , Parle-McDermott A. , Molloy A.M. , Brody L.C.
Mol. Genet. Metab.85:220-227(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NO ASSOCIATION OF VARIANTS MET-49; LEU-202 AND ARG-377 WITH SUSCEPTIBILITY TO FS-NTD

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