MUC16 ELISA Kit for Human(Homo sapiens) | EIAab.comMUC16 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MUC16(Gene name) > Human

MUC16 (Gene name),

Mucin-16 (Protein name ), MUC16_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MUC16(CA125);

Protein name:

Mucin-16(MUC-16);

Alternative:

Ovarian carcinoma antigen CA125;Ovarian cancer-related tumor marker CA125(CA-125);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds to MSLN. Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.

Function:

Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Secreted extracellular space May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain.

Protein Attributes:

Sequence length:

22152

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3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

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Related Databases

UniGene:

Hs.432676

KEGG:

hsa:94025

String:

Q8WXI7

Pfam:

PF01390

STRING:

9606.ENSP00000381008

SMR:

Q8WXI7

MIM:

606154

Uniprot:

Q8WXI7

FOR

ELISA Kit for Human MUC-16

Cat.:

E0154h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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CLIA Kit for Human MUC-16

Cat.:

U0154h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human MUC-16

Cat.:

P0154Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human MUC-16

Protein for Human MUC-16

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure."
O'Brien T.J. , Beard J.B. , Underwood L.J. , Shigemasa K.
Tumor Biol.23:154-169(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-10431;SEQUENCE REVISION TO N-TERMINUS;TISSUE SPECIFICITY;INDUCTION
2.

"The CA 125 gene: an extracellular superstructure dominated by repeat sequences."
O'Brien T.J. , Beard J.B. , Underwood L.J. , Dennis R.A. , Santin A.D. , York L.
Tumor Biol.22:348-366(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 10432-22152
3.

"Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16."
Yin B.W.T. , Lloyd K.O.
J. Biol. Chem.276:27371-27375(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8297-22152;PROTEIN SEQUENCE OF 21360-21365 AND 21983-21995;TISSUE SPECIFICITY
4.

Lloyd K.O. , Yin B.W.T.
Submitted (2003-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 20473-21695
tissue: Uterus.
6.

"CA125 phosphorylation is associated with its secretion from the WISH human amnion cell line."
Fendrick J.L. , Konishi I. , Geary S.M. , Parmley T.H. , Quirk J.G. Jr. , O'Brien T.J.
Tumor Biol.18:278-289(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION
7.

"Characterization of the oligosaccharides associated with the human ovarian tumor marker CA125."
Kui Wong N. , Easton R.L. , Panico M. , Sutton-Smith M. , Morrison J.C. , Lattanzio F.A. , Morris H.R. , Clark G.F. , Dell A. , Patankar M.S.
J. Biol. Chem.278:28619-28634(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION
8.

"Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion."
Rump A. , Morikawa Y. , Tanaka M. , Minami S. , Umesaki N. , Takeuchi M. , Miyajima A.
J. Biol. Chem.279:9190-9198(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MSLN
9.

"Introducing the MUC16 gene: implications for prevention and early detection in epithelial ovarian cancer."
McLemore M.R. , Aouizerat B.
Biol. Res. Nurs.6:262-267(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW;POLYMORPHISM
10.

"Mucin characteristics of human corneal-limbal epithelial cells that exclude the rose bengal anionic dye."
Argueso P. , Tisdale A. , Spurr-Michaud S. , Sumiyoshi M. , Gipson I.K.
Invest. Ophthalmol. Vis. Sci.47:113-119(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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