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Index > Protein center > Mcam(Gene name) > Mouse
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  • Mcam (Gene name),
  • Cell surface glycoprotein MUC18 (Protein name ),  MUC18_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Mcam(Muc18);
    Protein name:
    Cell surface glycoprotein MUC18;
    Alternative:
    Melanoma cell adhesion molecule;Gicerin;Melanoma-associated antigen MUC18;
    CD:
    CD146;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    648
    Sequence:
    50:
    MGLPKLVCVF | LFAACCCCRR | AAGVPGEEKQ | PVPTPDLVEA | EVGSTALLKC | 
    100:
    GPSRASGNFS | QVDWFLIHKE | RQILIFRVHQ | GKGQREPGEY | EHRLSLQDSV | 
    150:
    ATLALSHVTP | HDERMFLCKS | KRPRLQDHYV | ELQVFKAPEE | PTIQANVVGI | 
    200:
    HVDRQELREV | ATCVGRNGYP | IPQVLWYKNS | LPLQEEENRV | HIQSSQIVES | 
    250:
    SGLYTLKSVL | SARLVKEDKD | AQFYCELSYR | LPSGNHMKES | KEVTVPVFYP | 
    300:
    AEKVWVEVEP | VGLLKEGDHV | TIRCLTDGNP | QPHFTINKKD | PSTGEMEEES | 
    350:
    TDENGLLSLE | PAEKHHSGLY | QCQSLDLETT | ITLSSDPLEL | LVNYVSDVQV | 
    400:
    NPTAPEVQEG | ESLTLTCEAE | SNQDLEFEWL | RDKTGQLLGK | GPVLQLNNVR | 
    450:
    REAGGRYLCM | ASVPRVPGLN | RTQLVSVGIF | GSPWMALKER | KVWVQENAVL | 
    500:
    NLSCEASGHP | QPTISWNVNG | SATEWNPDPQ | TVVSTLNVLV | TPELLETGAE | 
    550:
    CTASNSLGSN | TTTIVLKLVT | LTTLIPDSSQ | TTGLSTLTVS | PHTRANSTST | 
    600:
    EKKLPQPESK | GVVIVAVIVC | TLVLAVLGAA | LYFFYKKGKL | PCGRSGKQEI | 
    648:
    TLPPTRKSEF | VVEVKSDKLP | EEMALLQGSN | GDKRAPGDQG | EKYIDLRH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cell surface glycoprotein MUC18
    Cat.:
    E1670h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Cell surface glycoprotein MUC18
    Cat.:
    E1670m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Cell surface glycoprotein MUC18
    Cat.:
    E1670r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Cell surface glycoprotein MUC18
    Cat.:
    U1670m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Cell surface glycoprotein MUC18
    Cat.:
    U1670r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cell surface glycoprotein MUC18
    Cat.:
    U1670h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse Cell surface glycoprotein MUC18
    Cat.:
    P1670Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cell surface glycoprotein MUC18
    Cat.:
    P1670Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cell surface glycoprotein MUC18
    Cat.:
    P1670Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Cell surface glycoprotein MUC18
    Monoclonal Antibody for Mouse Cell surface glycoprotein MUC18
    Monoclonal Antibody for Mouse Cell surface glycoprotein MUC18
    Protein for Mouse Cell surface glycoprotein MUC18
    Protein for Mouse Cell surface glycoprotein MUC18
    Protein for Mouse Cell surface glycoprotein MUC18

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    References
    1. 1.
      Taira E. , Okumura S. , Miki N.
      Submitted (1999-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      strain: BALB/c.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: FVB/N-3.
      tissue: Mammary tumor.
    3. 3.
      "HEMCAM/CD146 down regulates cell surface expression of beta-1 integrins."
      Alais S. , Allioli N. , Pujades C. , Duband J.-L. , Vainio O. , Imhof B.A. , Dunon D.
      J. Cell Sci.114:1847-1859(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 561-648 (ISOFORMS 1 AND 2)
    4. 4.
      "Isolation and characterization of mouse MUC18 cDNA gene, and correlation of MUC18 expression in mouse melanoma cell lines with metastatic ability."
      Yang H. , Wang S.-W. , Liu Z. , Wu M.-W.H. , McAlpine B. , Ansel J. , Armstrong C. , Wu G.-J.
      Gene265:133-145(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;ROLE IN MELANOMA
    5. 5.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-58 AND ASN-510
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