Protein name:
Murinoglobulin-2 (MuG2) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Function:
A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective.
Subcellular Location:
Secreted
Protein Attributes:
50:
MWKSRRAQLC | LFSVLLAFLP | SASSLNGDSK | YMVLVPSQLY | TETPEKICLH |
100:
LYHLNETVTV | TASLVSQTGR | RNLFDELVVD | KDLFQCVSFI | IPTLNSPDEE |
150:
EFLYVDIKGP | THEFSKRNAV | LVKNKESVVF | VQTDKPVYKP | GQSVKFRVVS |
200:
MDKTLRPLNE | LLPLAYIEDP | KKNRIMQWRD | IKTENGLKQM | SFSLAAEPIQ |
250:
GPYKIVVHKQ | SGVKEEHSFT | VMEFVLPRFN | VDLKVPNAIS | VNDEVLQVTV |
300:
CGKYTYGKPV | PGQVKISICH | ETEAGCKEVN | SKLDNNGCST | QEVNITELQS |
350:
KKRNYEVQLF | HVNATVTEEG | TGLEFNGYGT | TKIERITNKL | IFLKADSHFR |
400:
HGIPFFVKVR | LVDIKGDPIP | NERVFIKAQV | LGYTSATTTD | QHGLAKFSID |
450:
TAGFSGSSLH | IKVNHKGKDS | CYFFYCMEER | YASAEHVAYA | VYSLSKSYIY |
500:
LVKETSSILP | CNQIHTVQAH | FILKGDLGVL | KELVFYYLVM | AQGSIIQTGN |
550:
HTHQVEPGEA | PVKGNFDLEI | PVEFSMAPMA | KMLIYTILPD | GEVIADSVNF |
600:
EIEKCLRNKV | DLSFSSSQSL | PASQTRLQVT | ASPQSLCGLR | AVDQSVLLLK |
650:
PEDELSPSWI | YNLPGMQHNK | FIPSSSLSED | REDCILYSSW | VAEKHTDWVP |
700:
HGREKDVYRY | VEDMDLKAFT | NLKIKLPKIC | FDSAPMSGPR | GKFDLAFSSE |
750:
VSGTLQKGSS | KRPQPEEPPR | EDPPPKDPLA | ETIRKYFPET | WVWDIVTVNS |
800:
TGVAEVEMTV | PDTITEWKAG | ALCLSNDTGL | GLSSVVPLQA | FQPFFVEVSL |
850:
PYSVVRGEAF | MLKATVMNYL | PTSMRMSVQL | EASPDFTAVP | VGDDHDSYCL |
900:
SANGRHTSSW | LVTPKSLGNV | NFSVSVEAQQ | SSEPCGSEVA | TVPETGRKDT |
950:
VVKVLIVEPE | GIKQEHTFNS | LFCASDAEIS | EKMSLVLPPT | VVKDSARAHF |
1000:
SVMGDILSSA | IKNTQNLLHM | PYGCGEQNMV | LFAPNIYVLK | YLDKTQQLTQ |
1050:
KIKTKALGFL | RAGYQRELNY | KHKDGSYSAF | GDQNGEREGN | TWLTAFVLKS |
1100:
FAQARAFIFI | DESHITHAFT | WLSQQQKDNG | CFRSSGSLFH | NDIKHPVVSK |
1150:
ALSCLESSWK | TIEQGRNANF | VYTKALMAYA | FALAGNQDKR | NEILKSLDEE |
1200:
AIKEDNSIHW | ERPQKPRKSE | HNLYKPQASS | VEVEMNAYVV | LARLTAQPAP |
1250:
SPEDLTLSRS | TIMWLTKQQN | SNGGFSSTQD | TVVALDALSK | YGAVTFSRRQ |
1300:
KTSLVTIQST | GSFSQKFQVE | NSNCLLLQQV | PLPDIPGDYT | ISVSGEGCVY |
1350:
AQTTLRYNMH | LEKQQSAFAL | RVQTVPLTCN | NPKGHNSFQI | SLEISYTGSR |
1400:
PASNMVIADV | KMLSGFIPLK | PTVKKLERLE | HISRTEVSNN | NVLLYLDQVT |
1450:
NQTLAFSFII | QQDISVRNLQ | PAIVKVYDYY | ETDEVAYAEY | SSPCSSDKQN |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Polyclonal Antibody for Mouse MuG2
Polyclonal Antibody for Mouse MuG2
Monoclonal Antibody for Mouse MuG2
Monoclonal Antibody for Mouse MuG2
R&D Technical Data
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .