MYOCD ELISA Kit for Human(Homo sapiens) | EIAab.comMYOCD ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > MYOCD(Gene name) > Human

MYOCD (Gene name),

Myocardin (Protein name ), MYCD_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

MYOCD(MYCD);

Protein name:

Myocardin;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer. Interacts with SRF, its association does not depend on specific DNA sequences for ternary complex formation (By similarity). Interacts with MLLT7/FOXO4. Interacts (via C-terminal) with EP300 (via the CREB-binding domain). Interacts with HDAC4 and HDAC5 (By similarity). Interacts with MEF2C.

Function:

Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis).

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

938

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

938:

TPGFSALTTS | SPSIFNIDFL | DVTDLNLNSS | MDLHLQQW

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

Q8IZQ8

Pfam:

PF02755

UniGene:

Hs.462257

KEGG:

hsa:93649

STRING:

9606.ENSP00000341835

UniGene:

Hs.567641

String:

Q8IZQ8

MIM:

606127

Uniprot:

Q8IZQ8

FOR

ELISA Kit for Human Myocardin

Cat.:

E0535h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human Myocardin

Cat.:

E0535p

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human Myocardin

Cat.:

E0535r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human Myocardin

Cat.:

E0535m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Myocardin

Cat.:

U0535h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Myocardin

Cat.:

U0535p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Myocardin

Cat.:

U0535r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Myocardin

Cat.:

U0535m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human Myocardin

Cat.:

P0535Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Myocardin

Cat.:

P0535Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Myocardin

Cat.:

P0535Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Myocardin

Monoclonal Antibody for Human Myocardin

Protein for Human Myocardin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Potentiation of serum response factor activity by a family of myocardin-related transcription factors."
Wang D.-Z. , Li S. , Hockemeyer D. , Sutherland L. , Wang Z. , Schratt G. , Richardson J.A. , Nordheim A. , Olson E.N.
Proc. Natl. Acad. Sci. U.S.A.99:14855-14860(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation."
Du K.L. , Ip H.S. , Li J. , Chen M. , Dandre F. , Yu W. , Lu M.M. , Owens G.K. , Parmacek M.S.
Mol. Cell. Biol.23:2425-2437(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);FUNCTION;TISSUE SPECIFICITY
tissue: Heart.
3.

"Activation of cardiac and smooth muscle-specific genes in primary human cells after forced expression of human myocardin."
van Tuyn J. , Knaan-Shanzer S. , van de Watering M.J. , de Graaf M. , van der Laarse A. , Schalij M.J. , van der Wall E.E. , de Vries A.A. , Atsma D.E.
Cardiovasc. Res.67:245-255(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
tissue: Testis.
5.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
7.

"Myocardin mRNA is augmented in the failing myocardium: expression profiling in the porcine model and human dilated cardiomyopathy."
Torrado M. , Lopez E. , Centeno A. , Medrano C. , Castro-Beiras A. , Mikhailov A.T.
J. Mol. Med.81:566-577(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS 1; 2 AND 3);INDUCTION
8.

"Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin."
Liu Z.-P. , Wang Z. , Yanagisawa H. , Olson E.N.
Dev. Cell9:261-270(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MLLT7
9.

"Expression and functional activity of four myocardin isoforms."
Imamura M. , Long X. , Nanda V. , Miano J.M.
Gene464:1-10(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY OF ISOFORMS

Product Feedback Wall

* Email:
*Comments: