Protein name:
Myosin-2 ;
Alternative:
Myosin heavy chain 2a (MyHC-2a) ;Myosin heavy chain 2 ;Myosin heavy chain, skeletal muscle, adult 2 ;Myosin heavy chain IIa (MyHC-IIa) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).
Function:
Muscle contraction. Required for cytoskeleton organization.
Subcellular Location:
Cytoplasm
myofibril
Thick filaments of the myofibrils.
Protein Attributes:
50:
MSSDSELAVF | GEAAPFLRKS | ERERIEAQNR | PFDAKTSVFV | AEPKESFVKG |
100:
TIQSREGGKV | TVKTEGGATL | TVKDDQVFPM | NPPKYDKIED | MAMMTHLHEP |
150:
AVLYNLKERY | AAWMIYTYSG | LFCVTVNPYK | WLPVYKPEVV | TAYRGKKRQE |
200:
APPHIFSISD | NAYQFMLTDR | ENQSILITGE | SGAGKTVNTK | RVIQYFATIA |
250:
VTGEKKKEEI | TSGKIQGTLE | DQIISANPLL | EAFGNAKTVR | NDNSSRFGKF |
300:
IRIHFGTTGK | LASADIETYL | LEKSRVVFQL | KAERSYHIFY | QITSNKKPEL |
350:
IEMLLITTNP | YDYPFVSQGE | ISVASIDDQE | ELMATDSAID | ILGFTNEEKV |
400:
SIYKLTGAVM | HYGNLKFKQK | QREEQAEPDG | TEVADKAAYL | QSLNSADLLK |
450:
ALCYPRVKVG | NEYVTKGQTV | EQVSNAVGAL | AKAVYEKMFL | WMVARINQQL |
500:
DTKQPRQYFI | GVLDIAGFEI | FDFNSLEQLC | INFTNEKLQQ | FFNHHMFVLE |
550:
QEEYKKEGIE | WTFIDFGMDL | AACIELIEKP | MGIFSILEEE | CMFPKATDTS |
600:
FKNKLYDQHL | GKSANFQKPK | VVKGKAEAHF | ALIHYAGVVD | YNITGWLEKN |
650:
KDPLNETVVG | LYQKSAMKTL | AQLFSGAQTA | EGEGAGGGAK | KGGKKKGSSF |
700:
QTVSALFREN | LNKLMTNLRS | THPHFVRCII | PNETKTPGAM | EHELVLHQLR |
750:
CNGVLEGIRI | CRKGFPSRIL | YADFKQRYKV | LNASAIPEGQ | FIDSKKASEK |
800:
LLASIDIDHT | QYKFGHTKVF | FKAGLLGLLE | EMRDDKLAQL | ITRTQARCRG |
850:
FLARVEYQRM | VERREAIFCI | QYNIRSFMNV | KHWPWMKLFF | KIKPLLKSAE |
900:
TEKEMATMKE | EFQKIKDELA | KSEAKRKELE | EKMVTLLKEK | NDLQLQVQAE |
950:
AEGLADAEER | CDQLIKTKIQ | LEAKIKEVTE | RAEDEEEINA | ELTAKKRKLE |
1000:
DECSELKKDI | DDLELTLAKV | EKEKHATENK | VKNLTEEMAG | LDETIAKLTK |
1050:
EKKALQEAHQ | QTLDDLQAEE | DKVNTLTKAK | IKLEQQVDDL | EGSLEQEKKL |
1100:
RMDLERAKRK | LEGDLKLAQE | SIMDIENEKQ | QLDEKLKKKE | FEISNLQSKI |
1150:
EDEQALGIQL | QKKIKELQAR | IEELEEEIEA | ERASRAKAEK | QRSDLSRELE |
1200:
EISERLEEAG | GATSAQIEMN | KKREAEFQKM | RRDLEEATLQ | HEATAATLRK |
1250:
KHADSVAELG | EQIDNLQRVK | QKLEKEKSEM | KMEIDDLASN | VETVSKAKGN |
1300:
LEKMCRTLED | QLSELKSKEE | EQQRLINDLT | AQRGRLQTES | GEFSRQLDEK |
1350:
EALVSQLSRG | KQAFTQQIEE | LKRQLEEEIK | AKNALAHALQ | SSRHDCDLLR |
1400:
EQYEEEQESK | AELQRALSKA | NTEVAQWRTK | YETDAIQRTE | ELEEAKKKLA |
1450:
QRLQAAEEHV | EAVNAKCASL | EKTKQRLQNE | VEDLMLDVER | TNAACAALDK |
1500:
KQRNFDKILA | EWKQKCEETH | AELEASQKEA | RSLGTELFKI | KNAYEESLDQ |
1550:
LETLKRENKN | LQQEISDLTE | QIAEGGKRIH | ELEKIKKQVE | QEKCELQAAL |
1600:
EEAEASLEHE | EGKILRIQLE | LNQVKSEVDR | KIAEKDEEID | QLKRNHIRIV |
1650:
ESMQSTLDAE | IRSRNDAIRL | KKKMEGDLNE | MEIQLNHANR | MAAEALRNYR |
1700:
NTQGILKDTQ | IHLDDALRSQ | EDLKEQLAMV | ERRANLLQAE | IEELRATLEQ |
1750:
TERSRKIAEQ | ELLDASERVQ | LLHTQNTSLI | NTKKKLETDI | SQMQGEMEDI |
1800:
LQEARNAEEK | AKKAITDAAM | MAEELKKEQD | TSAHLERMKK | NMEQTVKDLQ |
1850:
LRLDEAEQLA | LKGGKKQIQK | LEARVRELEG | EVESEQKRNA | EAVKGLRKHE |
1900:
RRVKELTYQT | EEDRKNILRL | QDLVDKLQAK | VKSYKRQAEE | AEEQSNTNLA |
1941:
KFRKLQHELE | EAEERADIAE | SQVNKLRVKS | REVHTKVISE | E
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Pig
Dog
ELISA Kit for Human Myosin-2
ELISA Kit for Human Myosin-2
ELISA Kit for Human Myosin-2
ELISA Kit for Human Myosin-2
CLIA Kit for Human Myosin-2
CLIA Kit for Human Myosin-2
CLIA Kit for Human Myosin-2
CLIA Kit for Human Myosin-2
Polyclonal Antibody for Human Myosin-2
Polyclonal Antibody for Human Myosin-2
Polyclonal Antibody for Human Myosin-2
Polyclonal Antibody for Human Myosin-2
Monoclonal Antibody for Human Myosin-2
Monoclonal Antibody for Human Myosin-2
Monoclonal Antibody for Human Myosin-2
Monoclonal Antibody for Human Myosin-2
Protein for Human Myosin-2
Protein for Human Myosin-2
Protein for Human Myosin-2
Protein for Human Myosin-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Skeletal muscle .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Skeletal muscle .
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Nature440:1045-1049(2006)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Cerebellum .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1711-1941 (ISOFORM 1)
tissue :
Skeletal muscle .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1823-1941 (ISOFORM 1)
tissue :
Skeletal muscle .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH GCSAM
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT IBM3 LYS-706
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS ILE-970 AND VAL-1061