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Index > Protein center > MYLK(Gene name) > Bovine
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  • MYLK (Gene name),
  • Myosin light chain kinase, smooth muscle (Protein name ),  MYLK_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    MYLK;
    Protein name:
    Myosin light chain kinase, smooth muscle(MLCK);
    Alternative:
    Telokin;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    All isoforms including Telokin bind calmodulin. Interacts with SVIL. Binds to F-actin.
    Function:
    Calcium/calmodulin-dependent enzyme responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments. Also regulates actin-myosin interaction through a non-kinase activty.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    1176
    Sequence:
    50:
    MDFRANLQRQ | VKPKTLSEEE | RKVHGPQQVD | FRSVLAKKGT | PKTPVPEKVP | 
    100:
    PPKPATPDFR | SVLGSKKKLP | TENGSNNTEA | LNAKAAEGLK | PVGNAQPSGF | 
    150:
    LKPVGNAKLA | DTPKPLSSTK | PAETPKPLGN | VKPAETPKPL | GSTKPAETPK | 
    200:
    PLGSTKPAET | PKPLGNVKPA | ETPKPLGNIK | PTETPKPLGS | TKPAETPKPL | 
    250:
    GSTKPAETPK | PLGNVKPAET | PKPLGNVKPA | ETPKPLGNVK | PAETPKPVSN | 
    300:
    AKPAETLKPV | GNAKPAETPK | PLSNVKPAET | PKLVGNAKPA | ETSKPLDNAK | 
    350:
    PAEAPKPLGN | AKPAEIPKPT | GKEELKKEIK | NDVNCKKGHA | GATDSEKRPE | 
    400:
    SRGTAPTFEE | KLQDLHVAEG | QKLLLQCRVS | SDPPATITWT | LNGKTLKTTK | 
    450:
    FIVLSQEGSL | CSVSIEKALP | EDRGLYKCVA | KNSAGQAESS | CQVTVDVPDA | 
    500:
    PTSENAKAPE | MKARRPKSSL | PPVLGTESDA | TVKKKPAPKT | PPKAAMPPQI | 
    550:
    IQFPEDQKVR | AGESVELFGK | VAGTQPITCT | WMKFRKQIQD | SEHIKVENSE | 
    600:
    QGSKLTIRAA | RQEHCGCYTL | LVENKLGSRQ | AQVNLTVVDK | PDPPAGTPCA | 
    650:
    SDIRSSSLTL | SWYGSSYDGG | SAVQSYSVEI | WDSVDKTWKE | LATCRSTSFN | 
    700:
    VQDLLPDREY | KFRVRAINVY | GTSEPSQESE | LTALGEKPEE | EPKDEVEVSD | 
    750:
    DDEKEPEVDY | RTVTVNTEQK | VSDFYDIEER | LGSGKFGQVF | RLVEKKTGKI | 
    800:
    WAGKFFKAYS | AKEKENIRQE | ISIMNCLHHP | KLVQCVDAFE | EKANIVMVLE | 
    850:
    IVSGGELFER | IIDEDFELTE | RECIKYMKQI | SEGVEYIHKQ | GIVHLDLKPE | 
    900:
    NIMCVNKTGT | RIKLIDFGLA | RRLENAGSLK | VLFGTPEFVA | PEVINYEPIG | 
    950:
    YATDMWSIGV | ICYILVSGLS | PFMGDNDNET | LANVTSATWD | FDDEAFDEIS | 
    1000:
    DDAKDFISNL | LKKDMKNRLN | CTQCLQHPWL | MKDTKNMEAK | KLSKDRMKKY | 
    1050:
    MARRKWQKTG | NAVRAIGRLS | SMAMISGLSG | RKSSTGSPTS | PLNAEKLESE | 
    1100:
    DVSQAFLEAV | AEEKPHVKPY | FSKTIRDLEV | VEGSAARFDC | KIEGYPDPEV | 
    1150:
    VWFKDDQSIR | ESRHFQIDYD | EDGNCSLIIS | DVCGDDDAKY | TCKAVNSLGE | 
    1176:
    ATCTAELIVE | TMEEGEGEGG | EEEEEE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine MLCK
    Cat.:
    E1106h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine MLCK
    MSDS:
    Please sign in first.
    ELISA Kit for Bovine MLCK
    Cat.:
    E1106b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine MLCK
    MSDS:
    Please sign in first.
    ELISA Kit for Bovine MLCK
    Cat.:
    E1106c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine MLCK
    Cat.:
    E1106m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MLCK
    Cat.:
    U1106m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MLCK
    Cat.:
    U1106c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MLCK
    Cat.:
    U1106b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MLCK
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine MLCK
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine MLCK
    Cat.:
    U1106h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Bovine MLCK
    Cat.:
    P1106Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine MLCK
    Polyclonal Antibody for Bovine MLCK
    Polyclonal Antibody for Bovine MLCK
    Cat.:
    P1106Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine MLCK
    Polyclonal Antibody for Bovine MLCK
    Monoclonal Antibody for Bovine MLCK
    Monoclonal Antibody for Bovine MLCK
    Monoclonal Antibody for Bovine MLCK
    Monoclonal Antibody for Bovine MLCK
    Monoclonal Antibody for Bovine MLCK
    Monoclonal Antibody for Bovine MLCK
    Protein for Bovine MLCK
    Protein for Bovine MLCK
    Protein for Bovine MLCK
    Protein for Bovine MLCK
    Protein for Bovine MLCK
    Protein for Bovine MLCK

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    References
    1. 1.
      "Isolation of cDNA for bovine stomach 155 kDa protein exhibiting myosin light chain kinase activity."
      Kobayashi H. , Inoue A. , Mikawa T. , Kuwayama H. , Hotta Y. , Masaki T. , Ebashi S.
      J. Biochem.112:786-791(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Stomach.
    2. 2.
      "A novel regulatory effect of myosin light chain kinase from smooth muscle on the ATP-dependent interaction between actin and myosin."
      Kohama K. , Okagaki T. , Hayakawa K. , Lin Y. , Ishikawa R. , Shimmen T. , Inoue A.
      Biochem. Biophys. Res. Commun.184:1204-1211(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    3. 3.
      "The structure and function of the actin-binding domain of myosin light chain kinase of smooth muscle."
      Ye L.H. , Hayakawa K. , Kishi H. , Imamura M. , Nakamura A. , Okagaki T. , Takagi T. , Iwata A. , Tanaka T. , Kohama K.
      J. Biol. Chem.272:32182-32189(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACTIN-BINDING;CALMODULIN-BINDING
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