Protein name:
Myozenin-2 ;
Alternative:
FATZ-related protein 2 ;Calsarcin-1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts via its C-terminus with spectrin repeats 3 and 4 of ACTN2. Interacts with ATCN1, LDB3, MYOT and PPP3CA.
Function:
Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Subcellular Location:
Cytoplasm
myofibril
sarcomere
Z line
Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.
Protein Attributes:
50:
MLSHSAMVKQ | RKQQASAITK | EIHGHDVDGM | DLGKKVSIPR | DIMIEELSHF |
100:
SNRGARLFKM | RQRRSDKYTF | ENFQYESRAQ | INHNIAMQNG | RVDGSNLEGG |
150:
SQQGPSTPPN | TPDPRSPPNP | ENIAPGYSGP | LKEIPPERFN | TTAVPKYYRS |
200:
PWEQAIGSDP | ELLEALYPKL | FKPEGKAELR | DYRSFNRVAT | PFGGFEKASK |
250:
MVKFKVPDFE | LLLLTDPRFL | AFANPLSGRR | CFNRAPKGWV | SENIPVVITT |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
ELISA Kit for Mouse Myozenin-2
ELISA Kit for Mouse Myozenin-2
ELISA Kit for Mouse Myozenin-2
CLIA Kit for Mouse Myozenin-2
CLIA Kit for Mouse Myozenin-2
CLIA Kit for Mouse Myozenin-2
Polyclonal Antibody for Mouse Myozenin-2
Polyclonal Antibody for Mouse Myozenin-2
Polyclonal Antibody for Mouse Myozenin-2
Monoclonal Antibody for Mouse Myozenin-2
Monoclonal Antibody for Mouse Myozenin-2
Monoclonal Antibody for Mouse Myozenin-2
Protein for Mouse Myozenin-2
Protein for Mouse Myozenin-2
Protein for Mouse Myozenin-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Skeletal muscle .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Czech II .
tissue :
Mammary gland .
4.
"Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress."
Frey N.
,
Barrientos T.
,
Shelton J.M.
,
Frank D.
,
Rutten H.
,
Gehring D.
,
Kuhn C.
,
Lutz M.
,
Rothermel B.
,
Bassel-Duby R.
,
Richardson J.A.
,
Katus H.A.
,
Hill J.A.
,
Olson E.N.
Nat. Med.10:1336-1343(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-111;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .