NEK6 ELISA Kit for Pig(Sus scrofa) | EIAab.comNEK6 ELISA Kit for Pig(Sus scrofa)

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NEK6 (Gene name),

Serine/threonine-protein kinase Nek6 (Protein name ), NEK6_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

NEK6;

Protein name:

Serine/threonine-protein kinase Nek6;

Alternative:

Never in mitosis A-related kinase 6(NimA-related protein kinase 6);

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Interacts with NEK9, predominantly in mitosis. Interacts with KIF11 (via C-terminus). Interacts with APBB1 (via WW domain). Interacts with ANKRA2, ATF4, ARHGAP33, CDC42, CIR1, PRAM1, PTN, PRDX3, PIN1, RAD26L, RBBP6, RPS7, RPS6KB1, STAT3 and TRIP4.

Function:

Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.

Subcellular Location:

Cytoplasm Nucleus Nucleus speckle Cytoplasm cytoskeleton centrosome Cytoplasm cytoskeleton spindle pole Co-localizes with APBB1 at the nuclear speckles. Co-localizes with PIN1 in the nucleus. Co-localizes with ATF4, CIR1, ARHGAP33, ANKRA2, CDC42, NEK9, RAD26L, RBBP6, RPS7, TRIP4, RELB and PHF1 in the centrosome. Localizes to spindle microtubules in metaphase and anaphase and to the midbody during cytokinesis.

Protein Attributes:

Sequence length:

313

Sequence:

50:

100:

150:

200:

250:

300:

313:

QVARQMHVWT | SST

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Ssc.5362

Pfam:

PF00069

KEGG:

ssc:100514624

STRING:

9823.ENSSSCP00000005983

Uniprot:

A2BD05

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ELISA Kit for Pig Serine/threonine-protein kinase Nek6

Cat.:

E3081h

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96T

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ELISA Kit for Pig Serine/threonine-protein kinase Nek6

Cat.:

E3081m

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Packing:

96T

ELISA Kit for Pig Serine/threonine-protein kinase Nek6

Cat.:

E3081r

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96T

ELISA Kit for Pig Serine/threonine-protein kinase Nek6

Cat.:

E3081p

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Packing:

96T

CLIA Kit for Pig Serine/threonine-protein kinase Nek6

Cat.:

U3081h

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MSDS:

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Packing:

96T

CLIA Kit for Pig Serine/threonine-protein kinase Nek6

Cat.:

U3081m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig Serine/threonine-protein kinase Nek6

Cat.:

U3081p

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig Serine/threonine-protein kinase Nek6

Cat.:

U3081r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Pig Serine/threonine-protein kinase Nek6

Cat.:

P3081Rb-h

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40ug/0.2ml

Polyclonal Antibody for Pig Serine/threonine-protein kinase Nek6

Cat.:

P3081Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig Serine/threonine-protein kinase Nek6

Cat.:

P3081Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig Serine/threonine-protein kinase Nek6

Monoclonal Antibody for Pig Serine/threonine-protein kinase Nek6

Protein for Pig Serine/threonine-protein kinase Nek6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (NR6A1)."
Mikawa S. , Morozumi T. , Shimanuki S. , Hayashi T. , Uenishi H. , Domukai M. , Okumura N. , Awata T.
Genome Res.17:586-593(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: Large white X Landrace X Duroc.

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