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Index > Protein center > NEO1(Gene name) > Human
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  • NEO1 (Gene name),
  • Neogenin (Protein name ),  NEO1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NEO1(IGDCC2;NGN);
    Protein name:
    Neogenin;
    Alternative:
    Immunoglobulin superfamily DCC subclass member 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with RGMA.
    Function:
    May be involved as a regulatory protein in the transition of undifferentiated proliferating cells to their differentiated state. May also function as a cell adhesion molecule in a broad spectrum of embryonic and adult tissues.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1461
    Sequence:
    50:
    MAAERGARRL | LSTPSFWLYC | LLLLGRRAPG | AAAARSGSAP | QSPGASIRTF | 
    100:
    TPFYFLVEPV | DTLSVRGSSV | ILNCSAYSEP | SPKIEWKKDG | TFLNLVSDDR | 
    150:
    RQLLPDGSLF | ISNVVHSKHN | KPDEGYYQCV | ATVESLGTII | SRTAKLIVAG | 
    200:
    LPRFTSQPEP | SSVYAGNNAI | LNCEVNADLV | PFVRWEQNRQ | PLLLDDRVIK | 
    250:
    LPSGMLVISN | ATEGDGGLYR | CVVESGGPPK | YSDEVELKVL | PDPEVISDLV | 
    300:
    FLKQPSPLVR | VIGQDVVLPC | VASGLPTPTI | KWMKNEEALD | TESSERLVLL | 
    350:
    AGGSLEISDV | TEDDAGTYFC | IADNGNETIE | AQAELTVQAQ | PEFLKQPTNI | 
    400:
    YAHESMDIVF | ECEVTGKPTP | TVKWVKNGDM | VIPSDYFKIV | KEHNLQVLGL | 
    450:
    VKSDEGFYQC | IAENDVGNAQ | AGAQLIILEH | APATTGPLPS | APRDVVASLV | 
    500:
    STRFIKLTWR | TPASDPHGDN | LTYSVFYTKE | GIARERVENT | SHPGEMQVTI | 
    550:
    QNLMPATVYI | FRVMAQNKHG | SGESSAPLRV | ETQPEVQLPG | PAPNLRAYAA | 
    600:
    SPTSITVTWE | TPVSGNGEIQ | NYKLYYMEKG | TDKEQDVDVS | SHSYTINGLK | 
    650:
    KYTEYSFRVV | AYNKHGPGVS | TPDVAVRTLS | DVPSAAPQNL | SLEVRNSKSI | 
    700:
    MIHWQPPAPA | TQNGQITGYK | IRYRKASRKS | DVTETLVSGT | QLSQLIEGLD | 
    750:
    RGTEYNFRVA | ALTINGTGPA | TDWLSAETFE | SDLDETRVPE | VPSSLHVRPL | 
    800:
    VTSIVVSWTP | PENQNIVVRG | YAIGYGIGSP | HAQTIKVDYK | QRYYTIENLD | 
    850:
    PSSHYVITLK | AFNNVGEGIP | LYESAVTRPH | TDTSEVDLFV | INAPYTPVPD | 
    900:
    PTPMMPPVGV | QASILSHDTI | RITWADNSLP | KHQKITDSRY | YTVRWKTNIP | 
    950:
    ANTKYKNANA | TTLSYLVTGL | KPNTLYEFSV | MVTKGRRSST | WSMTAHGTTF | 
    1000:
    ELVPTSPPKD | VTVVSKEGKP | KTIIVNWQPP | SEANGKITGY | IIYYSTDVNA | 
    1050:
    EIHDWVIEPV | VGNRLTHQIQ | ELTLDTPYYF | KIQARNSKGM | GPMSEAVQFR | 
    1100:
    TPKADSSDKM | PNDQASGSGG | KGSRLPDLGS | DYKPPMSGSN | SPHGSPTSPL | 
    1150:
    DSNMLLVIIV | SVGVITIVVV | VIIAVFCTRR | TTSHQKKKRA | ACKSVNGSHK | 
    1200:
    YKGNSKDVKP | PDLWIHHERL | ELKPIDKSPD | PNPIMTDTPI | PRNSQDITPV | 
    1250:
    DNSMDSNIHQ | RRNSYRGHES | EDSMSTLAGR | RGMRPKMMMP | FDSQPPQPVI | 
    1300:
    SAHPIHSLDN | PHHHFHSSSL | ASPARSHLYH | PGSPWPIGTS | MSLSDRANST | 
    1350:
    ESVRNTPSTD | TMPASSSQTC | CTDHQDPEGA | TSSSYLASSQ | EEDSGQSLPT | 
    1400:
    AHVRPSHPLK | SFAVPAIPPP | GPPTYDPALP | STPLLSQQAL | NHHIHSVKTA | 
    1450:
    SIGTLGRSRP | PMPVVVPSAP | EVQETTRMLE | DSESSYEPDE | LTKEMAHLEG | 
    1461:
    LMKDLNAITT | A
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Pfam:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Neogenin
    Cat.:
    E1518h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Neogenin
    Cat.:
    E1518r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Neogenin
    Cat.:
    E1518m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Neogenin
    Cat.:
    U1518m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Neogenin
    Cat.:
    U1518h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Neogenin
    Cat.:
    U1518r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Neogenin
    Cat.:
    P1518Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Neogenin
    Cat.:
    P1518Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Neogenin
    Cat.:
    P1518Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Neogenin
    Monoclonal Antibody for Human Neogenin
    Monoclonal Antibody for Human Neogenin
    Protein for Human Neogenin
    Protein for Human Neogenin
    Protein for Human Neogenin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification and characterization of neogenin, a DCC-related gene."
      Meyerhardt J.A. , Look A.T. , Bigner S.H. , Fearon E.R.
      Oncogene14:1129-1136(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: Fetal brain.
    2. 2.
      "Molecular characterization of human neogenin, a DCC-related protein, and the mapping of its gene (NEO1) to chromosomal position 15q22.3-q23."
      Vielmetter J. , Chen X.-N. , Miskevich F. , Lane R.P. , Yamakawa K. , Korenberg J.R. , Dreyer W.J.
      Genomics41:414-421(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: Fetal brain.
    3. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 4)
      tissue: Brain.
    4. 5.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-210 AND ASN-489
      tissue: Plasma.
    5. 6.
      "Neogenin: A multi-functional receptor regulating diverse developmental processes."
      Cole S.J. , Bradford D. , Cooper H.M.
      Int. J. Biochem. Cell Biol.39:1569-1575(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    6. 7.
      "Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin."
      Kuns-Hashimoto R. , Kuninger D. , Nili M. , Rotwein P.
      Am. J. Physiol.294:C994-C1003(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RBMC
    7. 8.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-210; ASN-470 AND ASN-639
      tissue: Leukemic T-cell.
    8. 9.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    9. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH BMP FAMILY MEMBERS;MISCELLANEOUS
    10. 11.
      "The solution structure of the six fibronectin type III domains of human neogenin."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2005-11) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 429-1054
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