Nes ELISA Kit for Rat(Rattus norvegicus) | EIAab.comNes ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Nes(Gene name) > Rat

Nes (Gene name),

Nestin (Protein name ), NEST_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Nes;

Protein name:

Nestin;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, this protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25% (By similarity). Interacts with FHOD3.

Function:

Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

1893

Sequence:

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1850:

1893:

LQGQEVGALK | VPLVASPVHL | GPSQPLKFTL | SGVDGDSWSS | GED

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.9701

String:

P21263

Pfam:

PF00038

STRING:

10116.ENSRNOP00000025314

KEGG:

rno:25491

Uniprot:

P21263

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ELISA Kit for Rat Nestin

Cat.:

E2175r

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Rat Nestin

Cat.:

E2175h

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Packing:

96T

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ELISA Kit for Rat Nestin

Cat.:

E2175m

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Manual:

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Packing:

96T

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CLIA Kit for Rat Nestin

Cat.:

U2175m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Nestin

Cat.:

U2175h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat Nestin

Cat.:

U2175r

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Looking for manual.

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Packing:

96T

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Polyclonal Antibody for Rat Nestin

Cat.:

P2175Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Nestin

Cat.:

P2175Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Nestin

Cat.:

P2175Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Nestin

Protein for Rat Nestin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"CNS stem cells express a new class of intermediate filament protein."
Lendahl U. , Zimmerman L.B. , McKay R.D.G.
Cell60:585-595(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
2.

"Nestin promotes the phosphorylation-dependent disassembly of vimentin intermediate filaments during mitosis."
Chou Y.-H. , Khuon S. , Herrmann H. , Goldman R.D.
Mol. Biol. Cell14:1468-1478(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION
tissue: Glial tumor.
3.

"Mitotic reorganization of the intermediate filament protein nestin involves phosphorylation by cdc2 kinase."
Sahlgren C.M. , Mikhailov A. , Hellman J. , Chou Y.H. , Lendahl U. , Goldman R.D. , Eriksson J.E.
J. Biol. Chem.276:16456-16463(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 314-319;PHOSPHORYLATION AT THR-316
4.

"Fhos2, a novel formin-related actin-organizing protein, probably associates with the nestin intermediate filament."
Kanaya H. , Takeya R. , Takeuchi K. , Watanabe N. , Jing N. , Sumimoto H.
Genes Cells10:665-678(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FHOD3
5.

"Nestin is essential for mitogen-stimulated proliferation of neural progenitor cells."
Xue X.J. , Yuan X.B.
Mol. Cell. Neurosci.45:26-36(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
strain: Sprague-Dawley.

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