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Index > Protein center > Nhej1(Gene name) > Mouse
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  • Nhej1 (Gene name),
  • Non-homologous end-joining factor 1 (Protein name ),  NHEJ1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Nhej1(Xlf);
    Protein name:
    Non-homologous end-joining factor 1;
    Alternative:
    XRCC4-like factor;Protein cernunnos;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with XRCC4 and the XRCC4-LIG4 complex. Binds DNA in a length-dependent manner.
    Function:
    DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    295
    Sequence:
    50:
    MEELEQDLLL | QPWAWLQLAE | NSLLAKVSIT | KHGYALLISD | LQQVWHEQVD | 
    100:
    TSVVSQRAKE | LNKRLTAPPA | ALLCHLDEAL | RPLFKDSAHP | SKATFSCDRG | 
    150:
    EEGLILRVQS | ELSGLPFSWH | FHCIPASSSL | VSQHLIHPLM | GVSLALQSHV | 
    200:
    RELAALLRMK | DLEIQAYQES | GAVLSRSRLK | TEPFEENSFL | EQFMAEKLPE | 
    250:
    ACAVGDGKPF | AMSLQSLYVA | VTKQQIQARQ | AHKDSGETQA | SSSTSPRGTD | 
    295:
    NQPEEPVSLS | STLSEPEYEP | VAASGPMHRA | RLVKSKRKKP | RGLFS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    UniGene:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Non-homologous end-joining factor 1
    ELISA Kit for Mouse Non-homologous end-joining factor 1
    ELISA Kit for Mouse Non-homologous end-joining factor 1
    CLIA Kit for Mouse Non-homologous end-joining factor 1
    CLIA Kit for Mouse Non-homologous end-joining factor 1
    CLIA Kit for Mouse Non-homologous end-joining factor 1
    Polyclonal Antibody for Mouse Non-homologous end-joining factor 1
    Polyclonal Antibody for Mouse Non-homologous end-joining factor 1
    Polyclonal Antibody for Mouse Non-homologous end-joining factor 1
    Monoclonal Antibody for Mouse Non-homologous end-joining factor 1
    Monoclonal Antibody for Mouse Non-homologous end-joining factor 1
    Monoclonal Antibody for Mouse Non-homologous end-joining factor 1
    Protein for Mouse Non-homologous end-joining factor 1
    Protein for Mouse Non-homologous end-joining factor 1
    Protein for Mouse Non-homologous end-joining factor 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Testis.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: Czech II.
      tissue: Brain.
      tissue: Mammary tumor.
    3. 3.
      "Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells."
      Zha S. , Alt F.W. , Cheng H.-L. , Brush J.W. , Li G.
      Proc. Natl. Acad. Sci. U.S.A.104:4518-4523(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
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