Protein name:
Glutamate [NMDA] receptor subunit epsilon-3 (GluN2C) ;
Alternative:
N-methyl D-aspartate receptor subtype 2C (NMDAR2C) ;N-methyl D-aspartate receptor subtype 2C (NMDAR2C;NR2C) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with PDZ domains of INADL and DLG4 (By similarity). Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B).
Function:
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Cell junction
synapse
postsynaptic cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MGGALGPALL | LTSLLGAWAG | LGAGQGEQAV | TVAVVFGSSG | PLQAQARTRL |
100:
TPQNFLDLPL | EIQPLTIGVN | NTNPSSILTQ | ICGLLGAARV | HGIVFEDNVD |
150:
TEAVAQLLDF | VSSQTHVPIL | SISGGSAVVL | TPKEPGSAFL | QLGVSLEQQL |
200:
QVLFKVLEEY | DWSAFAVITS | LHPGHALFLE | GVRAVADASY | LSWRLLDVLT |
250:
LELGPGGPRA | RTQRLLRQVD | APVLVAYCSR | EEAEVLFAEA | AQAGLVGPGH |
300:
VWLVPNLALG | STDAPPAAFP | VGLISVVTES | WRLSLRQKVR | DGVAILALGA |
350:
HSYRRQYGTL | PAPAGDCRSH | PGPVSPAREA | FYRHLLNVTW | EGRDFSFSPG |
400:
GYLVQPTMVV | IALNRHRLWE | MVGRWDHGVL | YMKYPVWPRY | STSLQPVVDS |
450:
RHLTVATLEE | RPFVIVESPD | PGTGGCVPNT | VPCRRQSNHT | FSSGDITPYT |
500:
KLCCKGFCID | ILKKLAKVVK | FSYDLYLVTN | GKHGKRVRGV | WNGMIGEVYY |
550:
KRADMAIGSL | TINEERSEII | DFSVPFVETG | ISVMVARSNG | TVSPSAFLEP |
600:
YSPAVWVMMF | VMCLTVVAIT | VFMFEYFSPV | SYNQNLTKGK | KSGGPSFTIG |
650:
KSVWLLWALV | FNNSVPIENP | RGTTSKIMVL | VWAFFAVIFL | ASYTANLAAF |
700:
MIQEQYIDTV | SGLSDKKFQR | PQDQYPPFRF | GTVPNGSTER | NIRSNYRDMH |
750:
THMVKFNQRS | VEDALTSLKM | GKLDAFIYDA | AVLNYMAGKD | EGCKLVTIGS |
800:
GKVFATTGYG | IAMQKDSHWK | RAIDLALLQF | LGDGETQKLE | TVWLSGICHN |
850:
EKNEVMSSKL | DIDNMAGVFY | MLLVAMGLAL | LVFAWEHLVY | WKLRHSVPSS |
900:
SQLDFLLAFS | RGIYSCFNGV | QSLPSPARPP | SPDLTAGSAQ | ANVLKMLQAA |
950:
RDMVSTADVS | GSLDRATRTI | ENWGNNRRAP | APTTSGPRSC | TPGPPGQPSP |
1000:
SGWRPPGGGR | TPLARRAPQP | PARPATCAGS | PQPDVSRASC | RHAWDARWPV |
1050:
RVGHQGSHLS | ASERRALPER | SLLHAHCHYS | SFPRAERSGR | PFLPLFPEPP |
1100:
EPDDLPLLGP | EQLARREALL | RAAWARGPRP | RHASLPSSVA | EAFTRSNPLP |
1150:
ARCTGHACAC | PCPQSRPSCR | HVAQTQSLRL | PSYREACVEG | VPAGVAATWQ |
1200:
PRQHVCLHTH | THLPFCWGTV | CRHPPPCSSH | SPWLIGTWEP | PSHRGRTLGL |
1239:
GTGYRDSGVL | EEVSREACGT | QGFPRSCTWR | RISSLESEV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse GluN2C
ELISA Kit for Mouse GluN2C
ELISA Kit for Mouse GluN2C
CLIA Kit for Mouse GluN2C
CLIA Kit for Mouse GluN2C
CLIA Kit for Mouse GluN2C
Polyclonal Antibody for Mouse GluN2C
Polyclonal Antibody for Mouse GluN2C
Polyclonal Antibody for Mouse GluN2C
Monoclonal Antibody for Mouse GluN2C
Monoclonal Antibody for Mouse GluN2C
Monoclonal Antibody for Mouse GluN2C
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Molecular diversity of the NMDA receptor channel."
Kutsuwada T.
,
Kashiwabuchi N.
,
Mori H.
,
Sakimura K.
,
Kushiya E.
,
Araki K.
,
Meguro H.
,
Masaki H.
,
Kumanishi T.
,
Arakawa M.
,
Mishina M.
Nature358:36-41(1992)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION