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Index > Protein center > Grin2d(Gene name) > Rat
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  • Grin2d (Gene name),
  • Glutamate [NMDA] receptor subunit epsilon-4 (Protein name ),  NMDE4_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Grin2d(GluN2D);
    Protein name:
    Glutamate [NMDA] receptor subunit epsilon-4(GluN2D);
    Alternative:
    N-methyl D-aspartate receptor subtype 2D(NMDAR2D);N-methyl D-aspartate receptor subtype 2D(NMDAR2D;NR2D);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Interacts with PDZ domains of INADL and DLG4.
    Function:
    NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1323
    Sequence:
    50:
    MRGAGGPRGP | RGPAKMLLLL | ALACASPFPE | EVPGPGAVGG | GTGGARPLNV | 
    100:
    ALVFSGPAYA | AEAARLGPAV | AAAVRSPGLD | VRPVALVLNG | SDPRSLVLQL | 
    150:
    CDLLSGLRVH | GVVFEDDSRA | PAVAPILDFL | SAQTSLPIVA | VHGGAALVLT | 
    200:
    PKEKGSTFLQ | LGSSTEQQLQ | VIFEVLEEYD | WTSFVAVTTR | APGHRAFLSY | 
    250:
    IEVLTDGSLV | GWEHRGALTL | DPGAGEAVLG | AQLRSVSAQI | RLLFCAREEA | 
    300:
    EPVFRAAEEA | GLTGPGYVWF | MVGPQLAGGG | GSGVPGEPLL | LPGGSPLPAG | 
    350:
    LFAVRSAGWR | DDLARRVAAG | VAVVARGAQA | LLRDYGFLPE | LGHDCRTQNR | 
    400:
    THRGESLHRY | FMNITWDNRD | YSFNEDGFLV | NPSLVVISLT | RDRTWEVVGS | 
    450:
    WEQQTLRLKY | PLWSRYGRFL | QPVDDTQHLT | VATLEERPFV | IVEPADPISG | 
    500:
    TCIRDSVPCR | SQLNRTHSPP | PDAPRPEKRC | CKGFCIDILK | RLAHTIGFSY | 
    550:
    DLYLVTNGKH | GKKIDGVWNG | MIGEVFYQRA | DMAIGSLTIN | EERSEIVDFS | 
    600:
    VPFVETGISV | MVARSNGTVS | PSAFLEPYSP | AVWVMMFVMC | LTVVAVTVFI | 
    650:
    FEYLSPVGYN | RSLATGKRPG | GSTFTIGKSI | WLLWALVFNN | SVPVENPRGT | 
    700:
    TSKIMVLVWA | FFAVIFLASY | TANLAAFMIQ | EEYVDTVSGL | SDRKFQRPQE | 
    750:
    QYPPLKFGTV | PNGSTEKNIR | SNYPDMHSYM | VRYNQPRVEE | ALTQLKAGKL | 
    800:
    DAFIYDAAVL | NYMARKDEGC | KLVTIGSGKV | FATTGYGIAL | HKGSRWKRPI | 
    850:
    DLALLQFLGD | DEIEMLERLW | LSGICHNDKI | EVMSSKLDID | NMAGVFYMLL | 
    900:
    VAMGLSLLVF | AWEHLVYWRL | RHCLGPTHRM | DFLLAFSRGM | YSCCSAEAAP | 
    950:
    PPAKPPPPPQ | PLPSPAYPAA | RPPPGPAPFV | PRERAAADRW | RRAKGTGPPG | 
    1000:
    GAAIADGFHR | YYGPIEPQGL | GLGEARAAPR | GAAGRPLSPP | TTQPPQKPPP | 
    1050:
    SYFAIVREQE | PTEPPAGAFP | GFPSPPAPPA | AAAAAVGPPL | CRLAFEDESP | 
    1100:
    PAPSRWPRSD | PESQPLLGGG | AGGPSAGAPT | APPPRRAAPP | PCAYLDLEPS | 
    1150:
    PSDSEDSESL | GGASLGGLEP | WWFADFPYPY | AERLGPPPGR | YWSVDKLGGW | 
    1200:
    RAGSWDYLPP | RGGPAWHCRH | CASLELLPPP | RHLSCSHDGL | DGGWWAPPPP | 
    1250:
    PWAAGPPPRR | RARCGCPRPH | PHRPRASHRA | PAAAPHHHRH | RRAAGGWDFP | 
    1300:
    PPAPTSRSLE | DLSSCPRAAP | TRRLTGPSRH | ARRCPHAAHW | GPPLPTASHR | 
    1323:
    RHRGGDLGTR | RGSAHFSSLE | SEV
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat GluN2D
    Cat.:
    E11301h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat GluN2D
    Cat.:
    E11301r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat GluN2D
    Cat.:
    E11301m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat GluN2D
    Cat.:
    U11301m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat GluN2D
    Cat.:
    U11301h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat GluN2D
    Cat.:
    U11301r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat GluN2D
    Cat.:
    P11301Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat GluN2D
    Cat.:
    P11301Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat GluN2D
    Cat.:
    P11301Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat GluN2D
    Monoclonal Antibody for Rat GluN2D
    Monoclonal Antibody for Rat GluN2D
    Protein for Rat GluN2D
    Protein for Rat GluN2D
    Protein for Rat GluN2D

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits."
      Ishii T. , Moriyoshi K. , Sugihara H. , Sakurada K. , Kadotani H. , Yokoi M. , Akazawa C. , Shigemoto R. , Mizuno N. , Masu M. , Nakanishi S.
      J. Biol. Chem.268:2836-2843(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE OF 1265-1356 (ISOFORM 2)
      strain: Sprague-Dawley.
      tissue: Forebrain.
    2. 2.
      "Developmental and regional expression in the rat brain and functional properties of four NMDA receptors."
      Monyer H. , Burnashev N. , Laurie D.J. , Sakmann B. , Seeburg P.H.
      Neuron12:529-540(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Brain.
    3. 3.
      Boulter J. , Pecht G.
      Submitted (1994-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      strain: Sprague-Dawley.
      tissue: Brain.
    4. 4.
      "Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95."
      Kornau H.C. , Schenker L.T. , Kennedy M.B. , Seeburg P.H.
      Science269:1737-1740(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DLG4
    5. 5.
      "CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins."
      Kurschner C. , Mermelstein P.G. , Holden W.T. , Surmeier D.J.
      Mol. Cell. Neurosci.11:161-172(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH INADL
    6. 6.
      "Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors."
      Vance K.M. , Simorowski N. , Traynelis S.F. , Furukawa H.
      Nat. Commun.2:294-294(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 424-827;DISULFIDE BONDS
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