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Index > Protein center > NMT1(Gene name) > Human
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  • NMT1 (Gene name),
  • Glycylpeptide N-tetradecanoyltransferase 1 (Protein name ),  NMT1_HUMAN from NCBI database.
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  • Gene name:
    NMT1(NMT);
    Protein name:
    Glycylpeptide N-tetradecanoyltransferase 1;
    Alternative:
    Peptide N-myristoyltransferase 1;Myristoyl-CoA:protein N-myristoyltransferase 1(NMT 1;Type I N-myristoyltransferase);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    496
    Sequence:
    50:
    MADESETAVK | PPAPPLPQMM | EGNGNGHEHC | SDCENEEDNS | YNRGGLSPAN | 
    100:
    DTGAKKKKKK | QKKKKEKGSE | TDSAQDQPVK | MNSLPAERIQ | EIQKAIELFS | 
    150:
    VGQGPAKTME | EASKRSYQFW | DTQPVPKLGE | VVNTHGPVEP | DKDNIRQEPY | 
    200:
    TLPQGFTWDA | LDLGDRGVLK | ELYTLLNENY | VEDDDNMFRF | DYSPEFLLWA | 
    250:
    LRPPGWLPQW | HCGVRVVSSR | KLVGFISAIP | ANIHIYDTEK | KMVEINFLCV | 
    300:
    HKKLRSKRVA | PVLIREITRR | VHLEGIFQAV | YTAGVVLPKP | VGTCRYWHRS | 
    350:
    LNPRKLIEVK | FSHLSRNMTM | QRTMKLYRLP | ETPKTAGLRP | METKDIPVVH | 
    400:
    QLLTRYLKQF | HLTPVMSQEE | VEHWFYPQEN | IIDTFVVENA | NGEVTDFLSF | 
    450:
    YTLPSTIMNH | PTHKSLKAAY | SFYNVHTQTP | LLDLMSDALV | LAKMKGFDVF | 
    496:
    NALDLMENKT | FLEKLKFGIG | DGNLQYYLYN | WKCPSMGAEK | VGLVLQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Glycylpeptide N-tetradecanoyltransferase 1
    Cat.:
    E12020r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Glycylpeptide N-tetradecanoyltransferase 1
    Cat.:
    E12020b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Glycylpeptide N-tetradecanoyltransferase 1
    Cat.:
    E12020h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Glycylpeptide N-tetradecanoyltransferase 1
    Cat.:
    E12020m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Glycylpeptide N-tetradecanoyltransferase 1
    Cat.:
    U12020h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Glycylpeptide N-tetradecanoyltransferase 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Glycylpeptide N-tetradecanoyltransferase 1
    Cat.:
    U12020r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Glycylpeptide N-tetradecanoyltransferase 1
    Cat.:
    U12020m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Glycylpeptide N-tetradecanoyltransferase 1
    Polyclonal Antibody for Human Glycylpeptide N-tetradecanoyltransferase 1
    Cat.:
    P12020Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Glycylpeptide N-tetradecanoyltransferase 1
    Polyclonal Antibody for Human Glycylpeptide N-tetradecanoyltransferase 1
    Monoclonal Antibody for Human Glycylpeptide N-tetradecanoyltransferase 1
    Monoclonal Antibody for Human Glycylpeptide N-tetradecanoyltransferase 1
    Monoclonal Antibody for Human Glycylpeptide N-tetradecanoyltransferase 1
    Monoclonal Antibody for Human Glycylpeptide N-tetradecanoyltransferase 1
    Protein for Human Glycylpeptide N-tetradecanoyltransferase 1
    Protein for Human Glycylpeptide N-tetradecanoyltransferase 1
    Protein for Human Glycylpeptide N-tetradecanoyltransferase 1
    Protein for Human Glycylpeptide N-tetradecanoyltransferase 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human N-myristoyltransferase amino-terminal domain involved in targeting the enzyme to the ribosomal subcellular fraction."
      Glover C.J. , Hartman K.D. , Felsted R.L.
      J. Biol. Chem.272:28680-28689(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION
    2. 2.
      "A second mammalian N-myristoyltransferase."
      Giang D.K. , Cravatt B.F.
      J. Biol. Chem.273:6595-6598(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION
      tissue: Brain.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG)
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS LONG AND SHORT)
      tissue: Muscle.
      tissue: Skin.
    6. 6.
      "Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae."
      Duronio R.J. , Reed S.I. , Gordon J.I.
      Proc. Natl. Acad. Sci. U.S.A.89:4129-4133(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 58-496;MUTAGENESIS OF GLY-492
    7. 7.
      "Characterization of human and rat brain myristoyl-CoA:protein N-myristoyltransferase: evidence for an alternative splice variant of the enzyme."
      Mcilhinney R.A.J. , Young K. , Egerton M. , Camble R. , White A. , Soloviev M.
      Biochem. J.333:491-495(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 81-89
    8. 8.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-47;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-47;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-47;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-47;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "Crystal structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055."
      Structural genomics consortium (SGC)
      Submitted (2009-09) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.61 ANGSTROMS) OF 115-496 IN COMPLEX WITH MYRISTOYL-COA
    15. 15.
      "Global profiling of co- and post-translationally N-myristoylated proteomes in human cells."
      Thinon E. , Serwa R.A. , Broncel M. , Brannigan J.A. , Brassat U. , Wright M.H. , Heal W.P. , Wilkinson A.J. , Mann D.J. , Tate E.W.
      Nat. Commun.5:4919-4919(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.64 ANGSTROMS) OF 109-496 IN COMPLEX WITH MYRISTOYL-COA;CATALYTIC ACTIVITY;FUNCTION
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