Nos1 ELISA Kit for Mouse(Mus musculus) | EIAab.comNos1 ELISA Kit for Mouse(Mus musculus)

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Nos1 (Gene name),

Nitric oxide synthase, brain (Protein name ), NOS1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Nos1;

Protein name:

Nitric oxide synthase, brain;

Alternative:

NC-NOS;Constitutive NOS;Neuronal NOS(N-NOS;nNOS);NOS type I;bNOS;Peptidyl-cysteine S-nitrosylase NOS1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer. Forms a ternary complex with CAPON and SYN1. Interacts with ZDHHC23. Interacts with NOSIP; which may impair its synaptic location (By similarity). Interacts with DLG4; the interaction possibly being prevented by the association between NOS1 and CAPON. Interacts with HTR4. Forms a ternary complex with CAPON and RASD1. Interacts with VAC14 (By similarity). Interacts with SLC6A4.

Function:

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Isoform NNOS Mu may be an effector enzyme for the dystrophin complex.

Subcellular Location:

Cell membrane sarcolemma Peripheral membrane protein Cell projection dendritic spine In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines.

Protein Attributes:

Sequence length:

1429

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1429:

TYEVTNRLRS | ESIAFIEESK | KDTDEVFSS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9Z0J4

Pfam:

PF00667

UniGene:

Mm.442195

SMR:

Q9Z0J4

KEGG:

mmu:18125

Uniprot:

Q9Z0J4

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ELISA Kit for Mouse Nitric oxide synthase, brain

Cat.:

E0628r

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96T

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ELISA Kit for Mouse Nitric oxide synthase, brain

Cat.:

E0628h

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96T

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ELISA Kit for Mouse Nitric oxide synthase, brain

Cat.:

E0628m

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96T

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ELISA Kit for Mouse Nitric oxide synthase, brain

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CLIA Kit for Mouse Nitric oxide synthase, brain

MSDS:

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CLIA Kit for Mouse Nitric oxide synthase, brain

Cat.:

U0628h

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96T

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CLIA Kit for Mouse Nitric oxide synthase, brain

Cat.:

U0628r

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96T

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CLIA Kit for Mouse Nitric oxide synthase, brain

Cat.:

U0628m

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96T

Polyclonal Antibody for Mouse Nitric oxide synthase, brain

Cat.:

P0628Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Nitric oxide synthase, brain

Cat.:

P0628Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Nitric oxide synthase, brain

Cat.:

P0628Rb-r

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40ug/0.2ml

Monoclonal Antibody for Mouse Nitric oxide synthase, brain

Protein for Mouse Nitric oxide synthase, brain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Structural diversity of neuronal oxide synthase mRNA in the nervous system."
Ogura T. , Yokoyama T. , Fujisawa H. , Kurashima Y. , Esumi H.
Biochem. Biophys. Res. Commun.193:1014-1022(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS N-NOS-1 AND N-NOS-2)
strain: BALB/c.
tissue: Brain.
2.

"Neuronal nitric-oxide synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle."
Silvagno F. , Xia H. , Bredt D.S.
J. Biol. Chem.271:11204-11208(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM NNOS MU)
tissue: Skeletal muscle.
3.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1320-1429
strain: C57BL/6J.
tissue: Spinal ganglion.
4.

"Regulation of neuronal nitric oxide synthase through alternative transcripts."
Brenman J.E. , Xia H. , Chao D.S. , Black S.M. , Bredt D.S.
Dev. Neurosci.19:224-231(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS NNOS BETA; NNOS GAMMA AND NNOS MU)
5.

"Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95."
Tochio H. , Hung F. , Li M. , Bredt D.S. , Zhang M.
J. Mol. Biol.295:225-237(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DLG4
6.

"Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON."
Fang M. , Jaffrey S.R. , Sawa A. , Ye K. , Luo X. , Snyder S.H.
Neuron28:183-193(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RASD1 AND CAPON
7.

"New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting."
Joubert L. , Hanson B. , Barthet G. , Sebben M. , Claeysen S. , Hong W. , Marin P. , Dumuis A. , Bockaert J.
J. Cell Sci.117:5367-5379(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTR4
8.

"Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation."
Mustafa A.K. , Kumar M. , Selvakumar B. , Ho G.P. , Ehmsen J.T. , Barrow R.K. , Amzel L.M. , Snyder S.H.
Proc. Natl. Acad. Sci. U.S.A.104:2950-2955(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS NITROSYLASE
9.

"Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity."
Chanrion B. , Mannoury la Cour C. , Bertaso F. , Lerner-Natoli M. , Freissmuth M. , Millan M.J. , Bockaert J. , Marin P.
Proc. Natl. Acad. Sci. U.S.A.104:8119-8124(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SLC6A4
10.

"Crystal structure of calmodulin-neuronal nitric oxide synthase complex."
Valentine K.G. , Ng H.L. , Schneeweis L. , Kranz J.K. , Frederick K.K. , Alber T. , Wand A.J.
Submitted (2006-12) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 725-747 IN COMPLEX WITH CALMODULIN

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