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Index > Protein center > NOSIP(Gene name) > Human
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  • NOSIP (Gene name),
  • Nitric oxide synthase-interacting protein (Protein name ),  NOSIP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NOSIP(CGI-25);
    Protein name:
    Nitric oxide synthase-interacting protein;
    Alternative:
    eNOS-interacting protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with NOS1 and NOS3.
    Function:
    Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
    Subcellular Location:
    Cytoplasm Nucleus Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle.
    Protein Attributes:
    Sequence length:
    301
    Sequence:
    50:
    MTRHGKNCTA | GAVYTYHEKK | KDTAASGYGT | QNIRLSRDAV | KDFDCCCLSL | 
    100:
    QPCHDPVVTP | DGYLYEREAI | LEYILHQKKE | IARQMKAYEK | QRGTRREEQK | 
    150:
    ELQRAASQDH | VRGFLEKESA | IVSRPLNPFT | AKALSGTSPD | DVQPGPSVGP | 
    200:
    PSKDKDKVLP | SFWIPSLTPE | AKATKLEKPS | RTVTCPMSGK | PLRMSDLTPV | 
    250:
    HFTPLDSSVD | RVGLITRSER | YVCAVTRDSL | SNATPCAVLR | PSGAVVTLEC | 
    300:
    VEKLIRKDMV | DPVTGDKLTD | RDIIVLQRGG | TGFAGSGVKL | QAEKSRPVMQ | 
    301:
    A
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Nitric oxide synthase-interacting protein
    ELISA Kit for Human Nitric oxide synthase-interacting protein
    ELISA Kit for Human Nitric oxide synthase-interacting protein
    CLIA Kit for Human Nitric oxide synthase-interacting protein
    CLIA Kit for Human Nitric oxide synthase-interacting protein
    CLIA Kit for Human Nitric oxide synthase-interacting protein
    Polyclonal Antibody for Human Nitric oxide synthase-interacting protein
    Polyclonal Antibody for Human Nitric oxide synthase-interacting protein
    Polyclonal Antibody for Human Nitric oxide synthase-interacting protein
    Monoclonal Antibody for Human Nitric oxide synthase-interacting protein
    Monoclonal Antibody for Human Nitric oxide synthase-interacting protein
    Monoclonal Antibody for Human Nitric oxide synthase-interacting protein
    Protein for Human Nitric oxide synthase-interacting protein
    Protein for Human Nitric oxide synthase-interacting protein
    Protein for Human Nitric oxide synthase-interacting protein

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "NOSIP, a novel modulator of endothelial nitric oxide synthase activity."
      Dedio J. , Koenig P. , Wohlfart P. , Schroeder C. , Kummer W. , Mueller-Esterl W.
      FASEB J.15:79-89(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INTERACTION WITH NOS3;FUNCTION
    2. 2.
      "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
      Lai C.-H. , Chou C.-Y. , Ch'ang L.-Y. , Liu C.-S. , Lin W.-C.
      Genome Res.10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT MET-168
      tissue: B-cell.
      tissue: Brain.
      tissue: Placenta.
    4. 4.
      "Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity."
      Dreyer J. , Schleicher M. , Tappe A. , Schilling K. , Kuner T. , Kusumawidijaja G. , Mueller-Esterl W. , Oess S. , Kuner R.
      J. Neurosci.24:10454-10465(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NOS1;SUBCELLULAR LOCATION;FUNCTION
    5. 5.
      "Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton."
      Schleicher M. , Brundin F. , Gross S. , Mueller-Esterl W. , Oess S.
      Mol. Cell. Biol.25:8251-8258(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;FUNCTION
    6. 6.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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