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Index > Protein center > NOX1(Gene name) > Human
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  • NOX1 (Gene name),
  • NADPH oxidase 1 (Protein name ),  NOX1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NOX1(MOX1;NOH1);
    Protein name:
    NADPH oxidase 1(NOX-1);
    Alternative:
    NADH/NADPH mitogenic oxidase subunit P65-MOX;Mitogenic oxidase 1(MOX-1);NOH-1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    NOX1, NOXA1, NOXO1, RAC1 and CYBA forms a functional multimeric complex supporting ROS production. Interacts with NOXA1 and NOXO1.
    Function:
    NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.
    Subcellular Location:
    Cell projection invadopodium membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    564
    Sequence:
    50:
    MGNWVVNHWF | SVLFLVVWLG | LNVFLFVDAF | LKYEKADKYY | YTRKILGSTL | 
    100:
    ACARASALCL | NFNSTLILLP | VCRNLLSFLR | GTCSFCSRTL | RKQLDHNLTF | 
    150:
    HKLVAYMICL | HTAIHIIAHL | FNFDCYSRSR | QATDGSLASI | LSSLSHDEKK | 
    200:
    GGSWLNPIQS | RNTTVEYVTF | TSIAGLTGVI | MTIALILMVT | SATEFIRRSY | 
    250:
    FEVFWYTHHL | FIFYILGLGI | HGIGGIVRGQ | TEESMNESHP | RKCAESFEMW | 
    300:
    DDRDSHCRRP | KFEGHPPESW | KWILAPVILY | ICERILRFYR | SQQKVVITKV | 
    350:
    VMHPSKVLEL | QMNKRGFSME | VGQYIFVNCP | SISLLEWHPF | TLTSAPEEDF | 
    400:
    FSIHIRAAGD | WTENLIRAFE | QQYSPIPRIE | VDGPFGTASE | DVFQYEVAVL | 
    450:
    VGAGIGVTPF | ASILKSIWYK | FQCADHNLKT | KKIYFYWICR | ETGAFSWFNN | 
    500:
    LLTSLEQEME | ELGKVGFLNY | RLFLTGWDSN | IVGHAALNFD | KATDIVTGLK | 
    550:
    QKTSFGRPMW | DNEFSTIATS | HPKSVVGVFL | CGPRTLAKSL | RKCCHRYSSL | 
    564:
    DPRKVQFYFN | KENF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    SMR:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human NOX-1
    Cat.:
    E8866h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human NOX-1
    Cat.:
    E8866r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human NOX-1
    Cat.:
    E8866m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human NOX-1
    Cat.:
    U8866r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human NOX-1
    Cat.:
    U8866h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human NOX-1
    Cat.:
    U8866m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human NOX-1
    Cat.:
    P8866Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NOX-1
    Polyclonal Antibody for Human NOX-1
    Cat.:
    P8866Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human NOX-1
    Monoclonal Antibody for Human NOX-1
    Monoclonal Antibody for Human NOX-1
    Protein for Human NOX-1
    Protein for Human NOX-1
    Protein for Human NOX-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cell transformation by the superoxide-generating oxidase Mox1."
      Suh Y.-A. , Arnold R.S. , Lassegue B. , Shi J. , Xu X. , Sorescu D. , Chung A.B. , Griendling K.K. , Lambeth J.D.
      Nature401:79-82(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM NOH-1L)
      tissue: Colon epithelium.
    2. 2.
      "A mammalian H+ channel, generated through alternative splicing of the NADPH oxidase homolog NOH-1."
      Banfi B. , Maturana A. , Jaconi S. , Arnaudeau S. , Laforge T. , Sinha B. , Ligeti E. , Demaurex N. , Krause K.-H.
      Science287:138-142(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS NOH-1L; NOH-1LV AND NOH-1S)
    3. 3.
      NHLBI resequencing and genotyping service (RS&G)
      Submitted (2005-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM NOH-1L)
      tissue: Colon.
    5. 5.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM NOH-1L)
    8. 8.
      "NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain."
      Cheng G. , Lambeth J.D.
      J. Biol. Chem.279:4737-4742(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
    9. 9.
      "Molecular interaction of NADPH oxidase 1 with betaPix and Nox Organizer 1."
      Park H.S. , Park D. , Bae Y.S.
      Biochem. Biophys. Res. Commun.339:985-990(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NOXO1;ENZYME REGULATION
    10. 10.
      "Nox1-dependent reactive oxygen generation is regulated by Rac1."
      Cheng G. , Diebold B.A. , Hughes Y. , Lambeth J.D.
      J. Biol. Chem.281:17718-17726(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX CONTAINING NOX1; NOXO1; NOXA1 AND RAC1
    11. 11.
      "Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity."
      Gianni D. , Diaz B. , Taulet N. , Fowler B. , Courtneidge S.A. , Bokoch G.M.
      Sci. Signal.2:RA54-RA54(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    12. 12.
      "N-Linked glycosylation of the superoxide-producing NADPH oxidase Nox1."
      Miyano K. , Sumimoto H.
      Biochem. Biophys. Res. Commun.443:1060-1065(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-162 AND ASN-236
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