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Index > Protein center > NSL1(Gene name) > Human
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  • NSL1 (Gene name),
  • Kinetochore-associated protein NSL1 homolog (Protein name ),  NSL1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NSL1(DC8;DC31;MIS14;C1orf48);
    Protein name:
    Kinetochore-associated protein NSL1 homolog;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the MIS12 complex composed of MIS12, DSN1, NSL1/DC8 and PMF1. Interacts with CASC5.
    Function:
    Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.
    Subcellular Location:
    Nucleus Chromosome centromere kinetochore Associated with the kinetochore.
    Protein Attributes:
    Sequence length:
    281
    Sequence:
    50:
    MAGSPELVVL | DPPWDKELAA | GTESQALVSA | TPREDFRVRC | TSKRAVTEML | 
    100:
    QLCGRFVQKL | GDALPEEIRE | PALRDAQWTF | ESAVQENISI | NGQAWQEASD | 
    150:
    NCFMDSDIKV | LEDQFDEIIV | DIATKRKQYP | RKILECVIKT | IKAKQEILKQ | 
    200:
    YHPVVHPLDL | KYDPDPAPHM | ENLKCRGETV | AKEISEAMKS | LPALIEQGEG | 
    250:
    FSQVLRMQPV | IHLQRIHQEV | FSSCHRKPDA | KPENFITQIE | TTPTETASRK | 
    281:
    TSDMVLKRKQ | TKDCPQRKWY | PLRPKKINLD | T
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Kinetochore-associated protein NSL1 homolog
    ELISA Kit for Human Kinetochore-associated protein NSL1 homolog
    CLIA Kit for Human Kinetochore-associated protein NSL1 homolog
    CLIA Kit for Human Kinetochore-associated protein NSL1 homolog
    Polyclonal Antibody for Human Kinetochore-associated protein NSL1 homolog
    Polyclonal Antibody for Human Kinetochore-associated protein NSL1 homolog
    Monoclonal Antibody for Human Kinetochore-associated protein NSL1 homolog
    Monoclonal Antibody for Human Kinetochore-associated protein NSL1 homolog
    Protein for Human Kinetochore-associated protein NSL1 homolog
    Protein for Human Kinetochore-associated protein NSL1 homolog

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Novel genes expressed in human dendritic cell."
      Li Y. , Peng Y. , Li N. , Gu W. , Han Z. , Fu G. , Chen Z.
      Submitted (1999-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Dendritic cell.
    2. 2.
      Xu X. , Yang Y. , Gao G. , Xiao H. , Chen Z. , Han Z.
      Submitted (2000-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT VAL-254
      tissue: Dendritic cell.
    3. 3.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS PHE-4 AND VAL-254
      tissue: Urinary bladder.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 64-281 (ISOFORM 1)
      tissue: Kidney.
    6. 6.
      "A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1."
      Obuse C. , Iwasaki O. , Kiyomitsu T. , Goshima G. , Toyoda Y. , Yanagida M.
      Nat. Cell Biol.6:1135-1141(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DSN1 AND MIS12;SUBCELLULAR LOCATION
    7. 7.
      "The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation."
      Kline S.L. , Cheeseman I.M. , Hori T. , Fukagawa T. , Desai A.
      J. Cell Biol.173:9-17(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;COMPONENT OF MIS12 COMPLEX;SUBCELLULAR LOCATION
    8. 8.
      "Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1."
      Kiyomitsu T. , Obuse C. , Yanagida M.
      Dev. Cell13:663-676(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CASC5
    9. 9.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-244;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
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