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Index > Protein center > Mettl11a(Gene name) > Mouse
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  • Mettl11a (Gene name),
  • Alpha N-terminal protein methyltransferase 1A (Protein name ),  NTM1A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mettl11a(Mettl11a);
    Protein name:
    Alpha N-terminal protein methyltransferase 1A;
    Alternative:
    X-Pro-Lys N-terminal protein methyltransferase 1A(NTM1A);Methyltransferase-like protein 11A;X-Pro-Lys N-terminal protein methyltransferase 1A(NTM1A);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1 (By similarity). Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET.
    Subcellular Location:
    Nucleus Predominantly nuclear.
    Protein Attributes:
    Sequence length:
    223
    Sequence:
    50:
    MTSEVIEDEK | QFYSKAKTYW | KQIPPTVDGM | LGGYGHISNI | DLNSSRKFLQ | 
    100:
    RFLREGPNKT | GTSCALDCGA | GIGRITKRLL | LPLFRVVDMV | DVTEDFLAKA | 
    150:
    KTYLGEEGKR | VRNYFCCGLQ | DFSPEPGSYD | VIWIQWVIGH | LTDQHLAEFL | 
    200:
    RRCKRGLRPN | GIIVIKDNMA | QEGVILDDVD | SSVCRDLEVV | RRIIRTAGLS | 
    223:
    LLAEERQENL | PDEIYHVYSF | ALR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Alpha N-terminal protein methyltransferase 1A
    ELISA Kit for Mouse Alpha N-terminal protein methyltransferase 1A
    ELISA Kit for Mouse Alpha N-terminal protein methyltransferase 1A
    ELISA Kit for Mouse Alpha N-terminal protein methyltransferase 1A
    CLIA Kit for Mouse Alpha N-terminal protein methyltransferase 1A
    CLIA Kit for Mouse Alpha N-terminal protein methyltransferase 1A
    CLIA Kit for Mouse Alpha N-terminal protein methyltransferase 1A
    CLIA Kit for Mouse Alpha N-terminal protein methyltransferase 1A
    Polyclonal Antibody for Mouse Alpha N-terminal protein methyltransferase 1A
    Polyclonal Antibody for Mouse Alpha N-terminal protein methyltransferase 1A
    Polyclonal Antibody for Mouse Alpha N-terminal protein methyltransferase 1A
    Polyclonal Antibody for Mouse Alpha N-terminal protein methyltransferase 1A
    Monoclonal Antibody for Mouse Alpha N-terminal protein methyltransferase 1A
    Monoclonal Antibody for Mouse Alpha N-terminal protein methyltransferase 1A
    Monoclonal Antibody for Mouse Alpha N-terminal protein methyltransferase 1A
    Monoclonal Antibody for Mouse Alpha N-terminal protein methyltransferase 1A
    Protein for Mouse Alpha N-terminal protein methyltransferase 1A
    Protein for Mouse Alpha N-terminal protein methyltransferase 1A
    Protein for Mouse Alpha N-terminal protein methyltransferase 1A
    Protein for Mouse Alpha N-terminal protein methyltransferase 1A

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    Precision
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: NOD.
      tissue: Dendritic cell.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Czech II.
      tissue: Mammary tumor.
    5. 5.
      "NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein."
      Tooley C.E. , Petkowski J.J. , Muratore-Schroeder T.L. , Balsbaugh J.L. , Shabanowitz J. , Sabat M. , Minor W. , Hunt D.F. , Macara I.G.
      Nature466:1125-1128(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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