NTRK1 ELISA Kit for Human(Homo sapiens) | EIAab.comNTRK1 ELISA Kit for Human(Homo sapiens)

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NTRK1 (Gene name),

High affinity nerve growth factor receptor (Protein name ), NTRK1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

NTRK1(TRK;TRK;TRKA);

Protein name:

High affinity nerve growth factor receptor;

Alternative:

TRK1-transforming tyrosine kinase protein;Neurotrophic tyrosine kinase receptor type 1;Tyrosine kinase receptor;p140-TrkA(Trk-A);gp140trk;Tyrosine kinase receptor A(Trk-A);p140-TrkA;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. Binds SH2B2. Interacts with SQSTM1 which bridges NTRK1 to NGFR. Interacts with KIDINS220 and NGFR. Can form a ternary complex with NGFR and KIDINS220 and this complex is affected by the expression levels of KIDINS220. An increase in KIDINS220 expression leads to a decreased association of NGFR and NTRK1.

Function:

Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Endocytosed to the endosomes upon treatment of cells with NGF.

Protein Attributes:

Sequence length:

796

Sequence:

50:

100:

150:

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250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

796:

ACPPEVYAIM | RGCWQREPQQ | RHSIKDVHAR | LQALAQAPPV | YLDVLG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:4914

MIM:

164970

SMR:

P04629

Pfam:

PF07714

String:

P04629

UniGene:

Hs.406293

Uniprot:

P04629

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ELISA Kit for Human High affinity nerve growth factor receptor

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E9557h

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96T

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ELISA Kit for Human High affinity nerve growth factor receptor

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E9557m

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96T

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ELISA Kit for Human High affinity nerve growth factor receptor

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ELISA Kit for Human High affinity nerve growth factor receptor

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E9557r

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96T

CLIA Kit for Human High affinity nerve growth factor receptor

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CLIA Kit for Human High affinity nerve growth factor receptor

Cat.:

U9557r

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Packing:

96T

CLIA Kit for Human High affinity nerve growth factor receptor

Cat.:

U9557m

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96T

CLIA Kit for Human High affinity nerve growth factor receptor

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U9557h

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96T

Polyclonal Antibody for Human High affinity nerve growth factor receptor

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P9557Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human High affinity nerve growth factor receptor

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P9557Rb-m

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Polyclonal Antibody for Human High affinity nerve growth factor receptor

Monoclonal Antibody for Human High affinity nerve growth factor receptor

Protein for Human High affinity nerve growth factor receptor

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"Molecular and biochemical characterization of the human trk proto-oncogene."
Martin-Zanca D. , Oskam R. , Mitra G. , Copeland T.D. , Barbacid M.
Mol. Cell. Biol.9:24-33(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM TRKA-I)
tissue: Colon.
2.

"Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins."
Shelton D.L. , Sutherland J. , Gripp J. , Camerato T. , Armanini M.P. , Phillips H.S. , Carroll K. , Spencer S.D. , Levinson A.D.
J. Neurosci.15:477-491(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
3.

"Structure and organization of the human TRKA gene encoding a high affinity receptor for nerve growth factor."
Indo Y. , Mardy S. , Tsuruta M. , Karim M.A. , Matsuda I.
Jpn. J. Hum. Genet.42:343-351(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM TRKA-II);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-175 (ISOFORM 3)
tissue: Uterus.
5.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS TRKA-I AND TRKA-II)
tissue: Brain.
7.

"Methylation adjacent to negatively regulating AP-1 site reactivates TrkA gene expression during cancer progression."
Fujimoto M. , Kitazawa R. , Maeda S. , Kitazawa S.
Oncogene24:5108-5118(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-71
8.

"A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences."
Martin-Zanca D. , Hughes S.H. , Barbacid M.
Nature319:743-748(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 399-796;CHROMOSOMAL TRANSLOCATION WITH TPM3
9.

"Activation of the receptor kinase domain of the trk oncogene by recombination with two different cellular sequences."
Kozma S.C. , Redmond S.M.S. , Saurer S.M. , Groner B. , Hynes N.E.
EMBO J.7:147-154(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 399-796
10.

"The DNA rearrangement that generates the TRK-T3 oncogene involves a novel gene on chromosome 3 whose product has a potential coiled-coil domain."
Greco A. , Mariani C. , Miranda C. , Lupas A. , Pagliardini S. , Pomati M. , Pierotti M.A.
Mol. Cell. Biol.15:6118-6127(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 399-796;CHROMOSOMAL TRANSLOCATION WITH TFG
11.

"TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas."
Greco A. , Pierotti M.A. , Bongarzone I. , Pagliardini S. , Lanzi C. , Della Porta G.
Oncogene7:237-242(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 486-796;CHROMOSOMAL REARRANGEMENT WITH TPR
12.

"High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor."
Hempstead B.L. , Martin-Zanca D. , Kaplan D.R. , Parada L.F. , Chao M.V.
Nature350:678-683(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS RECEPTOR FOR NGF
13.

"The trk proto-oncogene encodes a receptor for nerve growth factor."
Klein R. , Jing S. , Nanduri V. , O'Rourke E. , Barbacid M.
Cell65:189-197(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NGF SIGNALING;IDENTIFICATION AS THE HIGH AFFINITY NGF RECEPTOR
14.

"Tissue-specific alternative splicing generates two isoforms of the trkA receptor."
Barker P.A. , Lomen-Hoerth C. , Gensch E.M. , Meakin S.O. , Glass D.J. , Shooter E.M.
J. Biol. Chem.268:15150-15157(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS TRKA-I AND TRKA-II);FUNCTION IN CELL SURVIVAL;NGF-BINDING;PHOSPHORYLATION;TISSUE SPECIFICITY
15.

"A Trk nerve growth factor (NGF) receptor point mutation affecting interaction with phospholipase C-gamma 1 abolishes NGF-promoted peripherin induction but not neurite outgrowth."
Loeb D.M. , Stephens R.M. , Copeland T.D. , Kaplan D.R. , Greene L.A.
J. Biol. Chem.269:8901-8910(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-791;INTERACTION WITH PLCG1;MUTAGENESIS OF TYR-791
16.

"Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses."
Stephens R.M. , Loeb D.M. , Copeland T.D. , Pawson T. , Greene L.A. , Kaplan D.R.
Neuron12:691-705(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NEURONAL DIFFERENTIATION;FUNCTION IN PHOSPHORYLATION OF SHC1 AND PLCG1;INTERACTION WITH SHC1;MUTAGENESIS OF TYR-496; LYS-544 AND TYR-791;PHOSPHORYLATION AT TYR-496 AND TYR-791
17.

"The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor."
Wooten M.W. , Seibenhener M.L. , Mamidipudi V. , Diaz-Meco M.T. , Barker P.A. , Moscat J.
J. Biol. Chem.276:7709-7712(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NF-KAPPA-B ACTIVATION;INTERACTION WITH SQSTM1
18.

"TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma."
Tacconelli A. , Farina A.R. , Cappabianca L. , Desantis G. , Tessitore A. , Vetuschi A. , Sferra R. , Rucci N. , Argenti B. , Screpanti I. , Gulino A. , Mackay A.R.
Cancer Cell6:347-360(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NEURONAL CELL PROLIFERATION AND DIFFERENTIATION;FUNCTION IN SIGNALING CASCADE ACTIVATION;NGF-BINDING;SUBCELLULAR LOCATION;ALTERNATIVE SPLICING (ISOFORM TRKA-III);CHARACTERIZATION OF ISOFORM TRKA-III;PHOSPHORYLATION AT TYR-496; TYR-680; TYR-681 AND TYR-791;INTERACTION WITH FRS2; GRB2; PIK3R1; PLCG1; SHC1;GLYCOSYLATION;TISSUE SPECIFICITY;INDUCTION BY HYPOXIA
19.

"Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling."
Vaegter C.B. , Jansen P. , Fjorback A.W. , Glerup S. , Skeldal S. , Kjolby M. , Richner M. , Erdmann B. , Nyengaard J.R. , Tessarollo L. , Lewin G.R. , Willnow T.E. , Chao M.V. , Nykjaer A.
Nat. Neurosci.14:54-61(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SORT1;ENZYME REGULATION
20.

"Structure and ligand recognition of the phosphotyrosine binding domain of Shc."
Zhou M.-M. , Ravichandran K.S. , Olejniczak E.F. , Petros A.M. , Meadows R.P. , Sattler M. , Harlan J.E. , Wade W.S. , Burakoff S.J. , Fesik S.W.
Nature378:584-592(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 489-500
21.

"Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC."
Ultsch M.H. , Wiesmann C. , Simmons L.C. , Henrich J. , Yang M. , Reilly D. , Bass S.H. , de Vos A.M.
J. Mol. Biol.290:149-159(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 278-386
22.

"Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor."
Wiesmann C. , Ultsch M.H. , Bass S.H. , de Vos A.M.
Nature401:184-188(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 282-382
23.

"Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors."
Wehrman T. , He X. , Raab B. , Dukipatti A. , Blau H. , Garcia K.C.
Neuron53:25-38(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF 36-382 IN COMPLEX WITH NGF;HOMODIMERIZATION;DISULFIDE BONDS;GLYCOSYLATION AT ASN-95; ASN-121; ASN-188; ASN-262; ASN-281 AND ASN-358
24.

"Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis."
Indo Y. , Tsuruta M. , Hayashida Y. , Karim M.A. , Ohta K. , Kawano T. , Mitsubuchi H. , Tonoki H. , Awaya Y. , Matsuda I.
Nat. Genet.13:485-488(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CIPA ARG-577
25.

"A novel NTRK1 mutation associated with congenital insensitivity to pain with anhidrosis."
Greco A. , Villa R. , Tubino B. , Romano L. , Penso D. , Pierotti M.A.
Am. J. Hum. Genet.64:1207-1210(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CIPA PRO-780
26.

"Congenital insensitivity to pain with anhidrosis: novel mutations in the TRKA (NTRK1) gene encoding a high-affinity receptor for nerve growth factor."
Mardy S. , Miura Y. , Endo F. , Matsuda I. , Sztriha L. , Frossard P. , Moosa A. , Ismail E.A.R. , Macaya A. , Andria G. , Toscano E. , Gibson W. , Graham G.E. , Indo Y.
Am. J. Hum. Genet.64:1570-1579(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CIPA PRO-213; TRP-649 AND SER-714;VARIANTS SER-85; TYR-604 AND VAL-613
27.

"Mutation analysis reveals novel sequence variants in NTRK1 in sporadic human medullary thyroid carcinoma."
Gimm O. , Greco A. , Hoang-Vu C. , Dralle H. , Pierotti M.A. , Eng C.
J. Clin. Endocrinol. Metab.84:2784-2787(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TYR-604; VAL-613 AND GLN-780
28.

"A novel point mutation affecting the tyrosine kinase domain of the TRKA gene in a family with congenital insensitivity to pain with anhidrosis."
Yotsumoto S. , Setoyama M. , Hozumi H. , Mizoguchi S. , Fukumaru S. , Kobayashi K. , Saheki T. , Kanzaki T.
J. Invest. Dermatol.112:810-814(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CIPA VAL-587
29.

"Characterization of single-nucleotide polymorphisms in coding regions of human genes."
Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.22:231-238(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TYR-604 AND VAL-613
30.

Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.23:373-373(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
31.

"Congenital insensitivity to pain with anhidrosis (CIPA) in Israeli-Bedouins: genetic heterogeneity, novel mutations in the TRKA/NGF receptor gene, clinical findings, and results of nerve conduction studies."
Shatzky S. , Moses S. , Levy J. , Pinsk V. , Hershkovitz E. , Herzog L. , Shorer Z. , Luder A. , Parvari R.
Am. J. Med. Genet.92:353-360(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CIPA LEU-695;VARIANT VAL-613
tissue: Peripheral blood.
32.

"Mutation and polymorphism analysis of the TRKA (NTRK1) gene encoding a high-affinity receptor for nerve growth factor in congenital insensitivity to pain with anhidrosis (CIPA) families."
Miura Y. , Mardy S. , Awaya Y. , Nihei K. , Endo F. , Matsuda I. , Indo Y.
Hum. Genet.106:116-124(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CIPA PRO-93; ARG-522; ARG-577; CYS-654 AND TYR-674
33.

"The Gly571Arg mutation, associated with the autonomic and sensory disorder congenital insensitivity to pain with anhidrosis, causes the inactivation of the NTRK1/nerve growth factor receptor."
Greco A. , Villa R. , Fusetti L. , Orlandi R. , Pierotti M.A.
J. Cell. Physiol.182:127-133(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CIPA ARG-577
34.

"A novel TRK A (NTRK1) mutation associated with hereditary sensory and autonomic neuropathy type V."
Houlden H. , King R.H. , Hashemi-Nejad A. , Wood N.W. , Mathias C.J. , Reilly M. , Thomas P.K.
Ann. Neurol.49:521-525(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CIPA CYS-359;VARIANTS TYR-604 AND VAL-613
35.

"Congenital insensitivity to pain with anhidrosis (CIPA): effect of TRKA (NTRK1) missense mutations on autophosphorylation of the receptor tyrosine kinase for nerve growth factor."
Mardy S. , Miura Y. , Endo F. , Matsuda I. , Indo Y.
Hum. Mol. Genet.10:179-188(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS CIPA PRO-93; PRO-213; ARG-522; ARG-577; TRP-649; CYS-654 AND SER-714;CHARACTERIZATION OF VARIANTS SER-85; TYR-604; VAL-613 AND TYR-674
36.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] ARG-80; VAL-107; MET-237; GLY-238; GLY-260; GLN-444; CYS-452; THR-566; TYR-604; VAL-613; GLN-780 AND ILE-790
37.

"Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohort."
Davidson G.L. , Murphy S.M. , Polke J.M. , Laura M. , Salih M.A. , Muntoni F. , Blake J. , Brandner S. , Davies N. , Horvath R. , Price S. , Donaghy M. , Roberts M. , Foulds N. , Ramdharry G. , Soler D. , Lunn M.P. , Manji H. , more...
J. Neurol.259:1673-1685(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CIPA LYS-492 AND CYS-654;VARIANT TRP-6

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