Gene name:
Nudt3 (Dipp;Dipp1) ;
Protein name:
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1;muDIPP1) ;
Alternative:
Nucleoside diphosphate-linked moiety X motif 3 (Nudix motif 3) ;3.6.1.-;Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1 ) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphophate) is not a substrate. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate (By similarity). Acts as a negative regulator of the ERK1/2 pathway.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MMKLKSNQTR | TYDGDGYKKR | AACLCFRSES | EEEVLLVSSS | RHPDRWIVPG |
100:
GGMEPEEEPS | VAAVREVCEE | AGVKGTLGRL | VGIFENQERK | HRTYVYVLIV |
150:
TEVLEDWEDS | VNIGRKREWF | KIEDAIKVLQ | CHKPVQASYF | ETLRQGYPAN |
168:
NGTPVVPTTY | SSSVSGIR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Bovine
Mouse
ELISA Kit for Mouse DIPP-1
ELISA Kit for Mouse DIPP-1
ELISA Kit for Mouse DIPP-1
ELISA Kit for Mouse DIPP-1
CLIA Kit for Mouse DIPP-1
CLIA Kit for Mouse DIPP-1
CLIA Kit for Mouse DIPP-1
CLIA Kit for Mouse DIPP-1
Polyclonal Antibody for Mouse DIPP-1
Polyclonal Antibody for Mouse DIPP-1
Polyclonal Antibody for Mouse DIPP-1
Polyclonal Antibody for Mouse DIPP-1
Monoclonal Antibody for Mouse DIPP-1
Monoclonal Antibody for Mouse DIPP-1
Monoclonal Antibody for Mouse DIPP-1
Monoclonal Antibody for Mouse DIPP-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 81-168
strain :
C57BL/6J .
tissue :
Spinal cord .