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Index > Protein center > Nudt3(Gene name) > Mouse
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  • Nudt3 (Gene name),
  • Diphosphoinositol polyphosphate phosphohydrolase 1 (Protein name ),  NUDT3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Nudt3(Dipp;Dipp1);
    Protein name:
    Diphosphoinositol polyphosphate phosphohydrolase 1(DIPP-1;muDIPP1);
    Alternative:
    Nucleoside diphosphate-linked moiety X motif 3(Nudix motif 3);3.6.1.-;Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphophate) is not a substrate. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate (By similarity). Acts as a negative regulator of the ERK1/2 pathway.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    168
    Sequence:
    50:
    MMKLKSNQTR | TYDGDGYKKR | AACLCFRSES | EEEVLLVSSS | RHPDRWIVPG | 
    100:
    GGMEPEEEPS | VAAVREVCEE | AGVKGTLGRL | VGIFENQERK | HRTYVYVLIV | 
    150:
    TEVLEDWEDS | VNIGRKREWF | KIEDAIKVLQ | CHKPVQASYF | ETLRQGYPAN | 
    168:
    NGTPVVPTTY | SSSVSGIR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse DIPP-1
    ELISA Kit for Mouse DIPP-1
    ELISA Kit for Mouse DIPP-1
    ELISA Kit for Mouse DIPP-1
    CLIA Kit for Mouse DIPP-1
    CLIA Kit for Mouse DIPP-1
    CLIA Kit for Mouse DIPP-1
    CLIA Kit for Mouse DIPP-1
    Polyclonal Antibody for Mouse DIPP-1
    Polyclonal Antibody for Mouse DIPP-1
    Polyclonal Antibody for Mouse DIPP-1
    Polyclonal Antibody for Mouse DIPP-1
    Monoclonal Antibody for Mouse DIPP-1
    Monoclonal Antibody for Mouse DIPP-1
    Monoclonal Antibody for Mouse DIPP-1
    Monoclonal Antibody for Mouse DIPP-1
    Protein for Mouse DIPP-1
    Protein for Mouse DIPP-1
    Protein for Mouse DIPP-1
    Protein for Mouse DIPP-1

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Ectopic expression of murine diphosphoinositol polyphosphate phosphohydrolase 1 attenuates signaling through the ERK1/2 pathway."
      Chu C. , Alapat D. , Wen X. , Timo K. , Burstein D. , Lisanti M. , Shears S. , Kohtz D.S.
      Cell. Signal.16:1045-1059(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;MUTAGENESIS OF GLU-70
      tissue: Heart.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      strain: FVB/N.
      tissue: Brain.
      tissue: Mammary tumor.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 81-168
      strain: C57BL/6J.
      tissue: Spinal cord.
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