Nuf2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comNuf2 ELISA Kit for Rat(Rattus norvegicus)

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Nuf2 (Gene name),

Kinetochore protein Nuf2 (Protein name ), NUF2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Nuf2(Cdca1);

Protein name:

Kinetochore protein Nuf2;

Alternative:

Cell division cycle-associated protein 1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Component of the NDC80 complex, which consists of NDC80/HEC1, CDCA1, SPBC24 and SPBC25. The NDC80 complex is formed by two subcomplexes composed of NDC80/HEC1-CDCA1 and SPBC24-SPBC25. Each subcomplex is formed by parallel interactions through the coiled-coil domains of individual subunits. Formation of a tetrameric complex is mediated by interactions between the C-terminal regions of both subunits of the NDC80/HEC1-CDCA1 subcomplex and the N-terminal regions of both subunits of the SPBC24-SPBC25 complex. The tetrameric NDC80 complex has an elongated rod-like structure with globular domains at either end. May interact with AURKB/Aurora-B.

Function:

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.

Subcellular Location:

Nucleus Chromosome centromere kinetochore Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.

Protein Attributes:

Sequence length:

464

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

464:

KTAELKRRMF | KMPP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.41428

SMR:

Q6AYL9

Pfam:

PF03800

STRING:

10116.ENSRNOP00000003650

KEGG:

rno:304951

String:

Q6AYL9

Uniprot:

Q6AYL9

FOR

ELISA Kit for Rat Kinetochore protein Nuf2

CLIA Kit for Rat Kinetochore protein Nuf2

Polyclonal Antibody for Rat Kinetochore protein Nuf2

Monoclonal Antibody for Rat Kinetochore protein Nuf2

Protein for Rat Kinetochore protein Nuf2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.

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