Protein name:
Outer dense fiber protein 2 ;
Alternative:
Outer dense fiber of sperm tails protein 2 ;Cenexin ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Self-associates. Associates with microtubules and forms a fibrillar structure partially linked to the microtubule network. Interacts via its C-terminus with PLK1. Interacts with ODF1.
Function:
Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
Subcellular Location:
Cytoplasm
cytoskeleton
centrosome
Cell projection
cilium
Cytoplasm
cytoskeleton
centrosome
centriole
Cytoplasm
cytoskeleton
spindle pole
Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.
Protein Attributes:
50:
MSASSSGGSP | RFPSCGKNGV | TSLTQKKVLR | APCGAPSVTV | TKSHKRGMKG |
100:
DTVNVRRSVR | VKTKVPWMPP | GKSSARPVGC | KWENPPHCLE | ITPPSSEKLV |
150:
SVMRLSDLST | EDDDSGHCKM | NRYDKKIDSL | MNAVGCLKSE | VKMQKGERQM |
200:
AKRFLEERKE | ELEEVAHELA | ETEHENTVLR | HNIERMKEEK | DFTILQKKHL |
250:
QQEKECLMSK | LVEAEMDGAA | AAKQVMALKD | TIGKLKTEKQ | MTCTDINTLT |
300:
RQKELLLQKL | STFEETNRTL | RDLLREQHCK | EDSERLMEQQ | GALLKRLAEA |
350:
DSEKARLLLL | LQDKDKEVEE | LLQEIQCEKA | QAKTASELSK | SMESMRGHLQ |
400:
AQLRSKEAEN | SRLCMQIKNL | ERSGNQHKAE | VEAIMEQLKE | LKQKGDRDKE |
450:
SLKKAIRAQK | ERAEKSEEYA | EQLHVQLADK | DLYVAEALST | LESWRSRYNQ |
500:
VVKEKGDLEL | EIIVLNDRVT | DLVNQQQTLE | EKMREDRDSL | VERLHRQTAE |
550:
YSAFKLENER | LKASFAPMED | KLNQAHLEVQ | QLKASVKNYE | GMIDNYKSQV |
600:
MKTRLEADEV | AAQLERCDKE | NKILKDEMNK | EIEAARRQFQ | SQLADLQQLP |
650:
DILKITEAKL | AECQDQLQGY | ERKNIDLTAI | ISDLRSRIEH | QGDKLEMARE |
700:
KHQASQKENK | QLSLKVDELE | RKLEATSAQN | IEFLQVIAKR | EEAIHQSQLR |
750:
LEEKTRECGT | LARQLESAIE | DARRQVEQTK | EHALSKERAA | QNKILDLETQ |
800:
LSRTKTELSQ | LRRSRDDADR | RYQSRLQDLK | DRLEQSESTN | RSMQNYVQFL |
829:
KSSYANVFGD | GPYSTFLTSS | PIRSRSPPA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Rat
Bovine
Human
Mouse
ELISA Kit for Human Outer dense fiber protein 2
ELISA Kit for Human Outer dense fiber protein 2
ELISA Kit for Human Outer dense fiber protein 2
ELISA Kit for Human Outer dense fiber protein 2
ELISA Kit for Human Outer dense fiber protein 2
CLIA Kit for Human Outer dense fiber protein 2
CLIA Kit for Human Outer dense fiber protein 2
CLIA Kit for Human Outer dense fiber protein 2
CLIA Kit for Human Outer dense fiber protein 2
CLIA Kit for Human Outer dense fiber protein 2
Polyclonal Antibody for Human Outer dense fiber protein 2
Polyclonal Antibody for Human Outer dense fiber protein 2
Polyclonal Antibody for Human Outer dense fiber protein 2
Polyclonal Antibody for Human Outer dense fiber protein 2
Polyclonal Antibody for Human Outer dense fiber protein 2
Monoclonal Antibody for Human Outer dense fiber protein 2
Monoclonal Antibody for Human Outer dense fiber protein 2
Monoclonal Antibody for Human Outer dense fiber protein 2
Monoclonal Antibody for Human Outer dense fiber protein 2
Monoclonal Antibody for Human Outer dense fiber protein 2
Protein for Human Outer dense fiber protein 2
Protein for Human Outer dense fiber protein 2
Protein for Human Outer dense fiber protein 2
Protein for Human Outer dense fiber protein 2
Protein for Human Outer dense fiber protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4);FUNCTION;ALTERNATIVE SPLICING;INTERACTION WITH PLK1
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Testis .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Eye .
tissue :
Testis .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .