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Index > Protein center > Odf2(Gene name) > Rat
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  • Odf2 (Gene name),
  • Outer dense fiber protein 2 (Protein name ),  ODFP2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Odf2(KKT4;Odf84);
    Protein name:
    Outer dense fiber protein 2;
    Alternative:
    Cenexin;84 kDa outer dense fiber protein;Outer dense fiber of sperm tails protein 2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Self-associates. Associates with microtubules and forms a fibrillar structure partially linked to the microtubule network. Interacts through its C-terminus with PLK1. Interacts with ODF1.
    Function:
    Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
    Subcellular Location:
    Cytoplasm cytoskeleton centrosome Cell projection cilium Cytoplasm cytoskeleton centrosome centriole Cytoplasm cytoskeleton spindle pole Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.
    Protein Attributes:
    Sequence length:
    825
    Sequence:
    50:
    MKDRSSTPPL | HVHVDENTPV | HVHIKKLPKP | SAASSQKSHK | RGMKGDTVNV | 
    100:
    RRSVRVKTKV | PWMPPGKSSA | RHVGCKWENP | PHCLEITPPS | SEKLVSVMRL | 
    150:
    SDLSTEDDDS | GHCKMNRYDK | KIDSLMNAVG | CLKSEVKMQK | GERQMAKRFL | 
    200:
    EERKEELEEV | AHELAETEHE | NTVLRHNIER | IKEEKDFTML | QKKHLQQEKE | 
    250:
    CLMSKLVEAE | MDGAAAAKQV | MALKDTIGKL | KTEKQMTCTD | INTLTRQKEL | 
    300:
    LLQKLSTFEE | TNRTLRDLLR | EQHCKEDSER | LMEQQGALLK | RLAEADSEKA | 
    350:
    RLLLLLQDKD | KEVEELLQEI | QCEKAQAKTA | SELSKSMESM | RGHLQAQLRC | 
    400:
    KEAENSRLCM | QIKNLERSGN | QHKAEVEAIM | EQLKELKQKG | DRDKETLKKA | 
    450:
    IRAQKERAEK | SEEYAEQLHV | QLADKDLYVA | EALSTLESWR | SRYNQVVKDK | 
    500:
    GDLELEIIVL | NDRVTDLVNQ | QQSLEEKMRE | DRDSLVERLH | RQTAEYSAFK | 
    550:
    LENERLKASF | APMEDKLNQA | HLEVQQLKAS | VKNYEGMIDN | YKSQVMKTRL | 
    600:
    EADEVAAQLE | RCDKENKMLK | DEMNKEIEAA | RRQFQSQLAD | LQQLPDILKI | 
    650:
    TEAKLAECQD | QLQGYERKNI | DLTAIISDLR | SRIEHQGDKL | ELAREKHQAS | 
    700:
    QKENKQLSQK | VDELERKLEA | TSTQNVEFLQ | VIAKREEAIH | QAQLRLEEKT | 
    750:
    RECGSLARQL | ESAIEDARRQ | VEQTKEQALS | KERAAQSKIL | DLETQLSRTK | 
    800:
    TELGQLRRTR | DDVDRRYQSR | LQDLKDRLEQ | SESTNRSMQN | YVQFLKSSYA | 
    825:
    NVFGDGPYTS | SYLTSSPIRS | RSPPA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Outer dense fiber protein 2
    ELISA Kit for Rat Outer dense fiber protein 2
    ELISA Kit for Rat Outer dense fiber protein 2
    ELISA Kit for Rat Outer dense fiber protein 2
    ELISA Kit for Rat Outer dense fiber protein 2
    CLIA Kit for Rat Outer dense fiber protein 2
    CLIA Kit for Rat Outer dense fiber protein 2
    CLIA Kit for Rat Outer dense fiber protein 2
    CLIA Kit for Rat Outer dense fiber protein 2
    CLIA Kit for Rat Outer dense fiber protein 2
    Polyclonal Antibody for Rat Outer dense fiber protein 2
    Polyclonal Antibody for Rat Outer dense fiber protein 2
    Polyclonal Antibody for Rat Outer dense fiber protein 2
    Polyclonal Antibody for Rat Outer dense fiber protein 2
    Polyclonal Antibody for Rat Outer dense fiber protein 2
    Monoclonal Antibody for Rat Outer dense fiber protein 2
    Monoclonal Antibody for Rat Outer dense fiber protein 2
    Monoclonal Antibody for Rat Outer dense fiber protein 2
    Monoclonal Antibody for Rat Outer dense fiber protein 2
    Monoclonal Antibody for Rat Outer dense fiber protein 2
    Protein for Rat Outer dense fiber protein 2
    Protein for Rat Outer dense fiber protein 2
    Protein for Rat Outer dense fiber protein 2
    Protein for Rat Outer dense fiber protein 2
    Protein for Rat Outer dense fiber protein 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Expression cloning of a rat testicular transcript abundant in germ cells, which contains two leucine zipper motifs."
      Turner K.J. , Sharpe R.M. , Gaughan J. , Millar M.R. , Foster P.M. , Saunders P.T.
      Biol. Reprod.57:1223-1232(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5);TISSUE SPECIFICITY;ALTERNATIVE SPLICING
      tissue: Testis.
    2. 2.
      "Identification and characterization of new cDNAs encoding outer dense fiber proteins of rat sperm."
      Brohmann H. , Pinnecke S. , Hoyer-Fender S.
      J. Biol. Chem.272:10327-10332(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4);TISSUE SPECIFICITY;ALTERNATIVE SPLICING
      strain: Sprague-Dawley.
      tissue: Spermatid.
    3. 3.
      "Developmental expression of the 84-kDa ODF sperm protein: localization to both the cortex and medulla of outer dense fibers and to the connecting piece."
      Schalles U. , Shao X. , van der Hoorn F.A. , Oko R.
      Dev. Biol.199:250-260(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);TISSUE SPECIFICITY
      tissue: Testis.
    4. 4.
      "Cenexin - a molecular scaffolding protein with dual functions in the mammalian centrosome and sperm tail."
      March P. , Sibley K.D. , Scott V. , Lange B.M.H. , Taylor S.S. , Gull K.
      Submitted (2001-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    5. 5.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Testis.
    7. 7.
      "Interactional cloning of the 84-kDa major outer dense fiber protein Odf84. Leucine zippers mediate associations of Odf84 and Odf27."
      Shao X. , Tarnasky H.A. , Schalles U. , Oko R. , van der Hoorn F.A.
      J. Biol. Chem.272:6105-6113(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ODP1;TISSUE SPECIFICITY
    8. 8.
      "Outer dense fibre protein 2 (ODF2) is a self-interacting centrosomal protein with affinity for microtubules."
      Donkor F.F. , Monnich M. , Czirr E. , Hollemann T. , Hoyer-Fender S.
      J. Cell Sci.117:4643-4651(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SELF-ASSOCIATION;SUBCELLULAR LOCATION
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