Ofd1 ELISA Kit for Mouse(Mus musculus) | EIAab.comOfd1 ELISA Kit for Mouse(Mus musculus)

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Ofd1 (Gene name),

Oral-facial-digital syndrome 1 protein homolog (Protein name ), OFD1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ofd1;

Protein name:

Oral-facial-digital syndrome 1 protein homolog;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homooligomer (By similarity). Interacts with LCA5 (By similarity). Interacts with RUVBL1; the interaction is direct and may mediate interaction with the NuA4 histone acetyltransferase complex (By similarity). Interacts with SDCCAG8; the interaction is direct.

Function:

Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis.

Subcellular Location:

Cytoplasm cytoskeleton centrosome centriole Cytoplasm cytoskeleton cilium basal body Nucleus Localizes to centriole distal ends.

Protein Attributes:

Sequence length:

1017

Sequence:

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1017:

KDESSPGFSH | EEPDDMW

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.247480

SMR:

Q80Z25

String:

Q80Z25

KEGG:

mmu:237222

Uniprot:

Q80Z25

FOR

ELISA Kit for Mouse Oral-facial-digital syndrome 1 protein homolog

CLIA Kit for Mouse Oral-facial-digital syndrome 1 protein homolog

Polyclonal Antibody for Mouse Oral-facial-digital syndrome 1 protein homolog

Monoclonal Antibody for Mouse Oral-facial-digital syndrome 1 protein homolog

Protein for Mouse Oral-facial-digital syndrome 1 protein homolog

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Characterization of the OFD1/Ofd1 genes on the human and mouse sex chromosomes and exclusion of Ofd1 for the Xpl mouse mutant."
Ferrante M.I. , Barra A. , Truong J.P. , Banfi S. , Disteche C.M. , Franco B.
Genomics81:560-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6J.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
3.

"Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification."
Ferrante M.I. , Zullo A. , Barra A. , Bimonte S. , Messaddeq N. , Studer M. , Dolle P. , Franco B.
Nat. Genet.38:112-117(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
4.

"Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms."
Corbit K.C. , Shyer A.E. , Dowdle W.E. , Gaulden J. , Singla V. , Chen M.H. , Chuang P.T. , Reiter J.F.
Nat. Cell Biol.10:70-76(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
5.

"Ofd1, a human disease gene, regulates the length and distal structure of centrioles."
Singla V. , Romaguera-Ros M. , Garcia-Verdugo J.M. , Reiter J.F.
Dev. Cell18:410-424(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF SER-73; ALA-78; GLY-137; 358-LYS--ASP-360 AND SER-435
6.

"Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites."
Tang Z. , Lin M.G. , Stowe T.R. , Chen S. , Zhu M. , Stearns T. , Franco B. , Zhong Q.
Nature502:254-257(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION

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