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Index > Protein center > Orc1(Gene name) > Mouse
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  • Orc1 (Gene name),
  • Origin recognition complex subunit 1 (Protein name ),  ORC1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Orc1(Orc1l);
    Protein name:
    Origin recognition complex subunit 1;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    ORC is composed of six subunits. Interacts with CDC6 and MYST2.
    Function:
    Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    840
    Sequence:
    50:
    MPSYLTRQKT | RQTFSWVGRP | LPNRKQFQQM | YREICMKIND | GSEIHIKVGQ | 
    100:
    FVLIQGEDNK | KPYVAKLIEL | FQNGAEVPPK | KCARVQWFVR | FLEIPVSKRH | 
    150:
    LLGRSPPAQE | IFWYDCSDWD | NKINVETIIG | PVQVVALAPE | EVIPVDQKSE | 
    200:
    ETLFVKLSWN | KKDFAPLPPE | VLAALREQED | SPEWQKPLKA | KIKNVKSPAR | 
    250:
    NTTEQEVKGI | KSNHSTSKFH | QTPANIVIPN | AKKSLELDGL | GFTRKPNTRW | 
    300:
    SKKSSCDSLD | YQKTSKRRAA | FSETTSPPKK | PNKPREIKPS | SALETRVKNG | 
    350:
    QTQPFCAKSS | VVLRARNPAM | TTTKLGVDNT | LSPIRNGLRS | SVVPSGGLTP | 
    400:
    VYIRRKAKEQ | ETHKEPIRTS | RVHRKSSLLT | LKRIRQQLCL | LDGDDRDQEE | 
    450:
    EESVDSESEE | EDEFISSLPT | RNSLGQSRTR | QTPSKSPQKN | PKPRTPHRAT | 
    500:
    PQIRDRNLAV | QEPASALEEA | RLRLHVSAVP | DSLPCREQEF | QDIYSFVESK | 
    550:
    LLDGTGGCMY | ISGVPGTGKT | ATVHEVIRCL | QQAAETDDVP | PFQYVEVNGM | 
    600:
    KLTEPHQVYV | QILKKLTGQK | ATANHAAELL | AKQFCGQGSQ | KETTVLLVDE | 
    650:
    LDLLWTHKQD | VMYNLFDWPT | HKGAHLIVLT | IANTMDLPER | IMMNRVSSRL | 
    700:
    GLTRMSFQPY | SHSQLKQILV | SRLRNLRAFE | DDAIQLVARK | VAALSGDARR | 
    750:
    CLDICRRATE | ICELSHLRGD | SLSLVTVAHL | MEAIDEMFSS | SYITAIKNSS | 
    800:
    VVEQSFLRAI | IAEFRRSGLE | EATFQQIYSQ | HVALCRMEGL | PYPTMSETMA | 
    840:
    VCSRLGSCRL | LLVEPSRNDL | LLRVRLNVSQ | NDVLFALKEE | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    SMR:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Origin recognition complex subunit 1
    ELISA Kit for Mouse Origin recognition complex subunit 1
    ELISA Kit for Mouse Origin recognition complex subunit 1
    ELISA Kit for Mouse Origin recognition complex subunit 1
    CLIA Kit for Mouse Origin recognition complex subunit 1
    CLIA Kit for Mouse Origin recognition complex subunit 1
    CLIA Kit for Mouse Origin recognition complex subunit 1
    CLIA Kit for Mouse Origin recognition complex subunit 1
    Polyclonal Antibody for Mouse Origin recognition complex subunit 1
    Polyclonal Antibody for Mouse Origin recognition complex subunit 1
    Polyclonal Antibody for Mouse Origin recognition complex subunit 1
    Polyclonal Antibody for Mouse Origin recognition complex subunit 1
    Monoclonal Antibody for Mouse Origin recognition complex subunit 1
    Monoclonal Antibody for Mouse Origin recognition complex subunit 1
    Monoclonal Antibody for Mouse Origin recognition complex subunit 1
    Monoclonal Antibody for Mouse Origin recognition complex subunit 1
    Protein for Mouse Origin recognition complex subunit 1
    Protein for Mouse Origin recognition complex subunit 1
    Protein for Mouse Origin recognition complex subunit 1
    Protein for Mouse Origin recognition complex subunit 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mouse homolog of the yeast origin recognition complex subunit ORC1 and chromosomal localization of the cognate mouse gene Orc1."
      Zisimopoulou P. , Staib C. , Nanda I. , Schmid M. , Grummt F.
      Mol. Gen. Genet.260:295-299(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Czech II.
      tissue: Mammary gland.
    4. 4.
      "The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome."
      Kuo A.J. , Song J. , Cheung P. , Ishibe-Murakami S. , Yamazoe S. , Chen J.K. , Patel D.J. , Gozani O.
      Nature484:115-119(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 9-170;INTERACTION WITH H4K20ME2
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