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Index > Protein center > Spp1(Gene name) > Mouse
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  • Spp1 (Gene name),
  • Osteopontin (Protein name ),  OSTP_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Spp1(Eta-1;Op;Spp-1);
    Protein name:
    Osteopontin;
    Alternative:
    Bone sialoprotein 1;2AR;Early T-lymphocyte activation 1 protein;Calcium oxalate crystal growth inhibitor protein;Secreted phosphoprotein 1(SPP-1);Minopontin;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Ligand for integrin alpha-V/beta-3.
    Function:
    Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    294
    Sequence:
    50:
    MRLAVICFCL | FGIASSLPVK | VTDSGSSEEK | LYSLHPDPIA | TWLVPDPSQK | 
    100:
    QNLLAPQNAV | SSEEKDDFKQ | ETLPSNSNES | HDHMDDDDDD | DDDDGDHAES | 
    150:
    EDSVDSDESD | ESHHSDESDE | TVTASTQADT | FTPIVPTVDV | PNGRGDSLAY | 
    200:
    GLRSKSRSFQ | VSDEQYPDAT | DEDLTSHMKS | GESKESLDVI | PVAQLLSMPS | 
    250:
    DQDNNGKGSH | ESSQLDEPSL | ETHRLEHSKE | SQESADQSDV | IDSQASSKAS | 
    294:
    LEHQSHKFHS | HKDKLVLDPK | SKEDDRYLKF | RISHELESSS | SEVN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Osteopontin
    Cat.:
    E0899h
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    ELISA Kit for Mouse Osteopontin
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    ELISA Kit for Mouse Osteopontin
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    E0899m
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    ELISA Kit for Mouse Osteopontin
    Cat.:
    E0899r
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    ELISA Kit for Mouse Osteopontin
    Cat.:
    E0899b
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    ELISA Kit for Mouse Osteopontin
    Cat.:
    E0899c
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    Packing:
    96T
    ELISA Kit for Mouse Osteopontin
    Cat.:
    E0899p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Osteopontin
    Cat.:
    U0899c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Osteopontin
    Cat.:
    U0899b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Osteopontin
    Cat.:
    U0899p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Osteopontin
    Cat.:
    U0899r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Osteopontin
    Cat.:
    U0899m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Osteopontin
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Osteopontin
    Cat.:
    U0899h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse Osteopontin
    Polyclonal Antibody for Mouse Osteopontin
    Polyclonal Antibody for Mouse Osteopontin
    Polyclonal Antibody for Mouse Osteopontin
    Cat.:
    P0899Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Osteopontin
    Polyclonal Antibody for Mouse Osteopontin
    Cat.:
    P0899Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Osteopontin
    Cat.:
    P0899Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Osteopontin
    Monoclonal Antibody for Mouse Osteopontin
    Monoclonal Antibody for Mouse Osteopontin
    Monoclonal Antibody for Mouse Osteopontin
    Monoclonal Antibody for Mouse Osteopontin
    Monoclonal Antibody for Mouse Osteopontin
    Monoclonal Antibody for Mouse Osteopontin
    Protein for Mouse Osteopontin
    Protein for Mouse Osteopontin
    Protein for Mouse Osteopontin
    Protein for Mouse Osteopontin
    Protein for Mouse Osteopontin
    Protein for Mouse Osteopontin
    Protein for Mouse Osteopontin

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    References
    1. 1.
      "Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis."
      Craig A.M. , Smith J.H. , Denhardt D.T.
      J. Biol. Chem.264:9682-9689(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection."
      Patarca R. , Freeman G.J. , Singh R.P. , Wei F.-Y. , Durfee T. , Blattner F. , Regnier D.C. , Kozak C.A. , Mock B.A. , Morse H.C. III , Jerrells T.R. , Cantor H.
      J. Exp. Med.170:145-161(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Nucleotide sequence of cDNA for mouse osteopontin-like protein."
      Miyazaki Y. , Setoguchi M. , Yoshida S. , Higuchi Y. , Akizuki S. , Yamamoto S.
      Nucleic Acids Res.17:3298-3298(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Macrophage.
    4. 4.
      "The mouse osteopontin gene. Expression in monocytic lineages and complete nucleotide sequence."
      Miyazaki Y. , Setoguchi M. , Yoshida S.Y. , Akizuki S. , Yamamoto S.
      J. Biol. Chem.265:14432-14438(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: BALB/c.
      tissue: Liver.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: NMRI.
      tissue: Mammary gland.
    6. 6.
      "The calcium oxalate crystal growth inhibitor protein produced by mouse kidney cortical cells in culture is osteopontin."
      Worcester E.M. , Blumenthal S.S. , Beshensky A.M. , Lewand D.L.
      J. Bone Miner. Res.7:1029-1036(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 17-37
      tissue: Kidney.
    7. 7.
      "Definition of a specific interaction between the early T lymphocyte activation 1 (Eta-1) protein and murine macrophages in vitro and its effect upon macrophages in vivo."
      Singh R.P. , Patarca R. , Schwartz J. , Singh P. , Cantor H.
      J. Exp. Med.171:1931-1942(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 158-176;FUNCTION
    8. 8.
      "Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity."
      Ashkar S. , Weber G.F. , Panoutsakopoulou V. , Sanchirico M.E. , Jansson M. , Zawaideh S. , Rittling S.R. , Denhardt D.T. , Glimcher M.J. , Cantor H.
      Science287:860-864(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-283; SER-288 AND SER-290;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    10. 10.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-283 AND SER-290;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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