Gene name:
Ppp2r3a (Ppp2r6) ;
Protein name:
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha ;
Alternative:
PP2A PR59 ;PP2A B''-PR59 ;Protein phosphatase 2A, 59 kDa regulatory subunit B ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.
Function:
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Interacts with retinoblastoma-related protein p107 (in vivo). May target PP2A core dimer to p107 resulting in dephosphorylation of p107.
Subcellular Location:
N/A
Protein Attributes:
50:
MPERPPIRAL | RRDPDDPAVA | QALASLARGS | DLVFPSRFQK | WLRDFRQVHA |
100:
HRKEEPPPQS | PPPGHTVPAF | YFPCGRPPPR | PQDTEDAIAL | VECAFEGLPR |
150:
GRAGLGDMAV | VAKACGCPLY | WKAPLFYAAG | GERTGSVSVH | MFVAMWRKVL |
200:
LTCHDDAARF | VRLLGHPGCS | GLIQEDFVPF | LQDVVNSHPG | LAFLRAAKDF |
250:
HSRYITTVIQ | RIFYTVNRSW | SGMISREELR | RSSFLQAVSQ | LEVEPDINRM |
300:
TSFFSYEHFY | VIYCKFWELD | LDRDLTIDRS | DLARHGDGAI | SSRMIDRIFS |
350:
GAVTRARLPR | KVGKLSYADF | VWFLLSEEDK | TTPTSTEYWF | RCMDLDGDGA |
400:
LSMFELEFFY | EEQAQRMAAR | GVEPLPFHDL | ARQVLDLVAP | RCPGRITLRD |
450:
LKQCGLAGEF | FDAFFNVDKY | LAREQREQAG | TPQDTDSDPA | ASAWDRYAAE |
491:
EYDFLVAEEA | MAEDDDDHDE | GSDPIDLYGL | ADEDCDDLEP | L
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
ELISA Kit for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
CLIA Kit for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
CLIA Kit for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Monoclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Monoclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Protein for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Protein for Mouse Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
R&D Technical Data
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Precision
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.