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Index > Protein center > Pla2g4a(Gene name) > Mouse
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  • Pla2g4a (Gene name),
  • Cytosolic phospholipase A2 (Protein name ),  PA24A_MOUSE from NCBI database.
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  • Gene name:
    Pla2g4a(Cpla2;Pla2g4);
    Protein name:
    Cytosolic phospholipase A2(cPLA2);
    Alternative:
    Phospholipase A2 group IVA;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
    Subcellular Location:
    Cytoplasm Cytoplasmic vesicle Translocates to membrane vesicles in a calcium-dependent fashion.
    Protein Attributes:
    Sequence length:
    748
    Sequence:
    50:
    MSFIDPYQHI | IVEHQYSHKF | TVVVLRATKV | TKGTFGDMLD | TPDPYVELFI | 
    100:
    STTPDSRKRT | RHFNNDINPV | WNETFEFILD | PNQENVLEIT | LMDANYVMDE | 
    150:
    TLGTATFPVS | SMKVGEKKEV | PFIFNQVTEM | ILEMSLEVCS | CPDLRFSMAL | 
    200:
    CDQEKTFRQQ | RKENIKENMK | KLLGPKKSEG | LYSTRDVPVV | AILGSGGGFR | 
    250:
    AMVGFSGVMK | ALYESGILDC | ATYIAGLSGS | TWYMSTLYSH | PDFPEKGPEE | 
    300:
    INEELMKNVS | HNPLLLLTPQ | KVKRYVESLW | KKKSSGQPVT | FTDIFGMLIG | 
    350:
    ETLIQNRMSM | TLSSLKEKVN | AARCPLPLFT | CLHVKPDVSE | LMFADWVEFS | 
    400:
    PYEIGMAKYG | TFMAPDLFGS | KFFMGTVVKK | YEENPLHFLM | GVWGSAFSIL | 
    450:
    FNRVLGVSGS | QNKGSTMEEE | LENITAKHIV | SNDSSDSDDE | AQGPKGTENE | 
    500:
    EAEKEYQSDN | QASWVHRMLM | ALVSDSALFN | TREGRAGKVH | NFMLGLNLNT | 
    550:
    SYPLSPLRDF | SSQDSFDDEL | DAAVADPDEF | ERIYEPLDVK | SKKIHVVDSG | 
    600:
    LTFNLPYPLI | LRPQRGVDLI | ISFDFSARPS | DTSPPFKELL | LAEKWAKMNK | 
    650:
    LPFPKIDPYV | FDREGLKECY | VFKPKNPDVE | KDCPTIIHFV | LANINFRKYK | 
    700:
    APGVLRETKE | EKEIADFDIF | DDPESPFSTF | NFQYPNQAFK | RLHDLMYFNT | 
    748:
    LNNIDVIKDA | IVESIEYRRQ | NPSRCSVSLS | NVEARKFFNK | EFLSKPTV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse cPLA2
    Cat.:
    E1624r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse cPLA2
    Cat.:
    E1624h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse cPLA2
    Cat.:
    E1624m
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse cPLA2
    Cat.:
    E1624b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse cPLA2
    Cat.:
    E1624c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse cPLA2
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse cPLA2
    Cat.:
    U1624b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse cPLA2
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse cPLA2
    Cat.:
    U1624m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse cPLA2
    Cat.:
    U1624r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse cPLA2
    Cat.:
    U1624h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse cPLA2
    Cat.:
    U1624c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse cPLA2
    Cat.:
    P1624Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse cPLA2
    Polyclonal Antibody for Mouse cPLA2
    Cat.:
    P1624Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse cPLA2
    Cat.:
    P1624Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse cPLA2
    Polyclonal Antibody for Mouse cPLA2
    Monoclonal Antibody for Mouse cPLA2
    Monoclonal Antibody for Mouse cPLA2
    Monoclonal Antibody for Mouse cPLA2
    Monoclonal Antibody for Mouse cPLA2
    Monoclonal Antibody for Mouse cPLA2
    Monoclonal Antibody for Mouse cPLA2
    Protein for Mouse cPLA2
    Protein for Mouse cPLA2
    Protein for Mouse cPLA2
    Protein for Mouse cPLA2
    Protein for Mouse cPLA2
    Protein for Mouse cPLA2

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    References
    1. 1.
      "A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP."
      Clark J.D. , Lin L.-L. , Kriz R.W. , Ramesha C.S. , Sultzman L.A. , Lin A.Y. , Milona N. , Knopf J.L.
      Cell65:1043-1051(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary tumor.
    3. 3.
      "Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases."
      Hefner Y. , Boersch-Haubold A.G. , Murakami M. , Wilde J.I. , Pasquet S. , Schieltz D. , Ghomashchi F. , Yates J.R. III , Armstrong C.G. , Paterson A. , Cohen P. , Fukunaga R. , Hunter T. , Kudo I. , Watson S.P. , Gelb M.H.
      J. Biol. Chem.275:37542-37551(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-505 AND SER-726;ACTIVATION
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    5. 5.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-437;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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