Gene name:
Papss2 (Atpsk2) ;
Protein name:
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPS synthase 2;PAPSS 2) ;
Alternative:
Sulfurylase kinase 2 (SK 2;SK2) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. May have a important role in skeletogenesis during postnatal growth.
Subcellular Location:
N/A
Protein Attributes:
50:
MSANFKMNHK | RDQQKSTNVV | YQAHHVSRNK | RGQVVGTRGG | FRGCTVWLTG |
100:
LSGAGKTTIS | FALEEYLVSH | AIPCYSLDGD | NVRHGLNKNL | GFSAGDREEN |
150:
IRRIAEVARL | FADAGLVCIT | SFISPFAKDR | ENARKIHESA | GLPFFEIFVD |
200:
APLNICESRD | VKGLYKRARA | GEIKGFTGID | SDYEKPETPE | CVLKTNLSSV |
250:
SDCVQQVVEL | LQEQNIVPHT | TIKGIHELFV | PENKVDQIRA | EAETLPSLPI |
300:
TKLDLQWVQI | LSEGWATPLK | GFMREKEYLQ | TLHFDTLLDG | VVPRDGVINM |
350:
SIPIVLPVSA | DDKARLEGCS | KFALMYEGRR | VALLQDPEFY | EHRKEERCSR |
400:
VWGTATAKHP | HIKMVMESGD | WLVGGDLQVL | ERIRWDDGLD | QYRLTPLELK |
450:
QKCKDMNADA | VFAFQLRNPV | HNGHALLMQD | TRRRLLERGY | KHPVLLLHPL |
500:
GGWTKDDDVP | LEWRMKQHAA | VLEERVLDPK | STIVAIFPSP | MLYAGPTEVQ |
550:
WHCRCRMIAG | ANFYIVGRDP | AGMPHPETKK | DLYEPTHGGK | VLSMAPGLTS |
600:
VEIIPFRVAA | YNKIKKAMDF | YDPARHEEFD | FISGTRMRKL | AREGEDPPDG |
621:
FMAPKAWKVL | TDYYRSLEKT | N
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse PAPS synthase 2
ELISA Kit for Mouse PAPS synthase 2
CLIA Kit for Mouse PAPS synthase 2
CLIA Kit for Mouse PAPS synthase 2
Polyclonal Antibody for Mouse PAPS synthase 2
Polyclonal Antibody for Mouse PAPS synthase 2
Monoclonal Antibody for Mouse PAPS synthase 2
Monoclonal Antibody for Mouse PAPS synthase 2
Protein for Mouse PAPS synthase 2
Protein for Mouse PAPS synthase 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT BM ARG-79
tissue :
Liver .
2.
"Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse."
ul Haque M.F.
,
King L.M.
,
Krakow D.
,
Cantor R.M.
,
Rusiniak M.E.
,
Swank R.T.
,
Superti-Furga A.
,
Haque S.
,
Abbas H.
,
Ahmad W.
,
Ahmad M.
,
Cohn D.H.
Nat. Genet.20:157-162(1998)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT BM ARG-79;VARIANT LYS-109
strain :
PWK .
tissue :
Spleen .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Kidney .