Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > PARP2(Gene name) > Human
  • Add your favorite
  • PARP2 (Gene name),
  • Poly [ADP-ribose] polymerase 2 (Protein name ),  PARP2_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    PARP2(ADPRT2;ADPRTL2);
    Protein name:
    Poly [ADP-ribose] polymerase 2(PARP-2;hPARP-2);
    Alternative:
    Poly[ADP-ribose] synthase 2(pADPRT-2);NAD(+) ADP-ribosyltransferase 2(ADPRT-2);Poly[ADP-ribose] synthase 2(pADPRT-2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of a base excision repair (BER) complex, containing at least XRCC1, PARP1, POLB and LRIG3. Homo- and heterodimer with PARP1.
    Function:
    Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    583
    Sequence:
    50:
    MAARRRRSTG | GGRARALNES | KRVNNGNTAP | EDSSPAKKTR | RCQRQESKKM | 
    100:
    PVAGGKANKD | RTEDKQDGMP | GRSWASKRVS | ESVKALLLKG | KAPVDPECTA | 
    150:
    KVGKAHVYCE | GNDVYDVMLN | QTNLQFNNNK | YYLIQLLEDD | AQRNFSVWMR | 
    200:
    WGRVGKMGQH | SLVACSGNLN | KAKEIFQKKF | LDKTKNNWED | REKFEKVPGK | 
    250:
    YDMLQMDYAT | NTQDEEETKK | EESLKSPLKP | ESQLDLRVQE | LIKLICNVQA | 
    300:
    MEEMMMEMKY | NTKKAPLGKL | TVAQIKAGYQ | SLKKIEDCIR | AGQHGRALME | 
    350:
    ACNEFYTRIP | HDFGLRTPPL | IRTQKELSEK | IQLLEALGDI | EIAIKLVKTE | 
    400:
    LQSPEHPLDQ | HYRNLHCALR | PLDHESYEFK | VISQYLQSTH | APTHSDYTMT | 
    450:
    LLDLFEVEKD | GEKEAFREDL | HNRMLLWHGS | RMSNWVGILS | HGLRIAPPEA | 
    500:
    PITGYMFGKG | IYFADMSSKS | ANYCFASRLK | NTGLLLLSEV | ALGQCNELLE | 
    550:
    ANPKAEGLLQ | GKHSTKGLGK | MAPSSAHFVT | LNGSTVPLGP | ASDTGILNPD | 
    583:
    GYTLNYNEYI | VYNPNQVRMR | YLLKVQFNFL | QLW
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    Pfam:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human PARP-2
    Cat.:
    E9945h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human PARP-2
    Cat.:
    E9945m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human PARP-2
    Cat.:
    U9945h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human PARP-2
    Cat.:
    U9945m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human PARP-2
    Cat.:
    P9945Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PARP-2
    Cat.:
    P9945Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human PARP-2
    Monoclonal Antibody for Human PARP-2
    Protein for Human PARP-2
    Protein for Human PARP-2

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Fetal brain.
    2. 2.
      "A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues."
      Johansson M.
      Genomics57:442-445(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-583 (ISOFORM 1)
      tissue: Fetal brain.
    3. 3.
      "pADPRT-2: a novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans."
      Berghammer H. , Ebner M. , Marksteiner R. , Auer B.
      FEBS Lett.449:259-263(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 22-583 (ISOFORM 1)
      tissue: Fibroblast.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    5. 5.
      NIEHS SNPs program
      Submitted (2002-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ASN-161; SER-168; GLY-235; VAL-285 AND GLN-296
    6. 6.
      "Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1."
      Schreiber V. , Ame J.-C. , Dolle P. , Schultz I. , Rinaldi B. , Fraulob V. , Menissier-de Murcia J. , de Murcia G.M.
      J. Biol. Chem.277:23028-23036(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PARP1; XRCC1; POLB AND LRIG3
    7. 7.
      "Toward a unified nomenclature for mammalian ADP-ribosyltransferases."
      Hottiger M.O. , Hassa P.O. , Luscher B. , Schuler H. , Koch-Nolte F.
      Trends Biochem. Sci.35:208-219(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NOMENCLATURE
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-226 AND SER-232;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888."
      Karlberg T. , Hammarstrom M. , Schutz P. , Svensson L. , Schuler H.
      Biochemistry49:1056-1058(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) OF 235-579 IN COMPLEX WITH PARP INHIBITORS;SUBUNIT
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a KSR2 Gdf5
    Top Searches
    Ubiquitin-protein ligase Ubiquitin ELISA metalloproteinase Tumor necrosis Asprosin TRAP1A Alpha
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    Twitter