Protein name:
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) ;
Alternative:
Propanoyl-CoA:carbon dioxide ligase subunit alpha ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits.
Subcellular Location:
Mitochondrion matrix
Protein Attributes:
50:
MAGQWVRTVA | LLAARRHWRR | SSQQQLLGTL | KHAPVYSYQC | LVVSRSLSSV |
100:
EYEPKEKTFD | KILIANRGEI | ACRVIKTCKK | MGIKTVAIHS | DVDASSVHVK |
150:
MADEAVCVGP | APTSKSYLNM | DAIMEAIKKT | RAQAVHPGYG | FLSENKEFAK |
200:
RLAAEDVTFI | GPDTHAIQAM | GDKIESKLLA | KRAKVNTIPG | FDGVVKDADE |
250:
AVRIAREIGY | PVMIKASAGG | GGKGMRIAWD | DEETRDGFRF | SSQEAASSFG |
300:
DDRLLIEKFI | DNPRHIEIQV | LGDKHGNALW | LNERECSIQR | RNQKVVEEAP |
350:
SIFLDPETRQ | AMGEQAVALA | KAVKYSSAGT | VEFLVDSQKN | FYFLEMNTRL |
400:
QVEHPVTECI | TGLDLVQEMI | LVAKGYPLRH | KQEDIPISGW | AVECRVYAED |
450:
PYKSFGLPSI | GRLSQYQEPI | HLPGVRVDSG | IQPGSDISIY | YDPMISKLVT |
500:
YGSDRAEALK | RMEDALDNYV | IRGVTHNIPL | LREVIINTRF | VKGDISTKFL |
550:
SDVYPDGFKG | HTLTLSERNQ | LLAIASSVFV | ASQLRAQRFQ | EHSRVPVIRP |
600:
DVAKWELSVK | LHDEDHTVVA | SNNGPAFTVE | VDGSKLNVTS | TWNLASPLLS |
650:
VNVDGTQRTV | QCLSREAGGN | MSIQFLGTVY | KVHILTKLAA | ELNKFMLEKV |
700:
PKDTSSTLCS | PMPGVVVAVS | VKPGDMVAEG | QEICVIEAMK | MQNSMTAGKM |
724:
GKVKLVHCKA | GDTVGEGDLL | VELE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse PCCase subunit alpha
ELISA Kit for Mouse PCCase subunit alpha
ELISA Kit for Mouse PCCase subunit alpha
CLIA Kit for Mouse PCCase subunit alpha
CLIA Kit for Mouse PCCase subunit alpha
CLIA Kit for Mouse PCCase subunit alpha
Polyclonal Antibody for Mouse PCCase subunit alpha
Polyclonal Antibody for Mouse PCCase subunit alpha
Polyclonal Antibody for Mouse PCCase subunit alpha
Monoclonal Antibody for Mouse PCCase subunit alpha
Monoclonal Antibody for Mouse PCCase subunit alpha
Monoclonal Antibody for Mouse PCCase subunit alpha
Protein for Mouse PCCase subunit alpha
Protein for Mouse PCCase subunit alpha
Protein for Mouse PCCase subunit alpha
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Fatal propionic acidemia in mice lacking propionyl-CoA carboxylase and its rescue by postnatal, liver-specific supplementation via a transgene."
Miyazaki T.
,
Ohura T.
,
Kobayashi M.
,
Shigematsu Y.
,
Yamaguchi S.
,
Suzuki Y.
,
Hata I.
,
Aoki Y.
,
Yang X.
,
Minjares C.
,
Haruta I.
,
Uto H.
,
Ito Y.
,
Muller U.
J. Biol. Chem.276:35995-35999(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Embryo .
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-248;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
4.
"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J.
,
Chen Y.
,
Tishkoff D.X.
,
Peng C.
,
Tan M.
,
Dai L.
,
Xie Z.
,
Zhang Y.
,
Zwaans B.M.
,
Skinner M.E.
,
Lombard D.B.
,
Zhao Y.
Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-61; LYS-115; LYS-146; LYS-184; LYS-196; LYS-258; LYS-324; LYS-381; LYS-403; LYS-498; LYS-509; LYS-554 AND LYS-644;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
5.
"Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
Rardin M.J.
,
Newman J.C.
,
Held J.M.
,
Cusack M.P.
,
Sorensen D.J.
,
Li B.
,
Schilling B.
,
Mooney S.D.
,
Kahn C.R.
,
Verdin E.
,
Gibson B.W.
Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-61; LYS-146; LYS-150; LYS-196; LYS-324 AND LYS-492;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .