Protein name:
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Function:
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
Subcellular Location:
Cytoplasm
Located mostly to soluble cellular fractions.
Protein Attributes:
50:
MRIEERKSQH | LTGLTDEKVK | AYLSLHPQVL | DEFVSESVSA | ETVEKWLKRK |
100:
NNKSEDESAP | KEVSRYQDTN | MQGVVYELNS | YIEQRLDTGG | DNQLLLYELS |
150:
SIIKIATKAD | GFALYFLGEC | NNSLCIFTPP | GIKEGKPRLI | PAGPITQGTT |
200:
VSAYVAKSRK | TLLVEDILGD | ERFPRGTGLE | SGTRIQSVLC | LPIVTAIGDL |
250:
IGILELYRHW | GKEAFCLSHQ | EVATANLAWA | SVAIHQVQVC | RGLAKQTELN |
300:
DFLLDVSKTY | FDNIVAIDSL | LEHIMIYAKN | LVNADRCALF | QVDHKNKELY |
350:
SDLFDIGEEK | EGKPVFKKTK | EIRFSIEKGI | AGQVARTGEV | LNIPDAYADP |
400:
RFNREVDLYT | GYTTRNILCM | PIVSRGSVIG | VVQMVNKISG | SAFSKTDENN |
450:
FKMFAVFCAL | ALHCANMYHR | IRHSECIYRV | TMEKLSYHSI | CTSEEWQGLM |
500:
QFTLPVRLCK | EIELFHFDIG | PFENMWPGIF | VYMVHRSCGT | SCFELEKLCR |
550:
FIMSVKKNYR | RVPYHNWKHA | VTVAHCMYAI | LQNNHTLFTD | LERKGLLIAC |
600:
LCHDLDHRGF | SNSYLQKFDH | PLAALYSTST | MEQHHFSQTV | SILQLEGHNI |
650:
FSTLSSSEYE | QVLEIIRKAI | IATDLALYFG | NRKQLEEMYQ | TGSLNLNNQS |
700:
HRDRVIGLMM | TACDLCSVTK | LWPVTKLTAN | DIYAEFWAEG | DEMKKLGIQP |
750:
IPMMDRDKKD | EVPQGQLGFY | NAVAIPCYTT | LTQILPPTEP | LLKACRDNLS |
779:
QWEKVIRGEE | TATWISSPSV | AQKAAASED
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
ELISA Kit for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
ELISA Kit for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
CLIA Kit for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
CLIA Kit for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
CLIA Kit for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Polyclonal Antibody for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Polyclonal Antibody for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Polyclonal Antibody for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Monoclonal Antibody for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Monoclonal Antibody for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Monoclonal Antibody for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Protein for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Protein for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Protein for Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM PDE10A1)
tissue :
Colon .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS) OF 436-766 IN COMPLEXES WITH AMP; CAMP; GMP; CGMP AND MAGNESIUM;MUTAGENESIS OF ASP-554;FUNCTION;COFACTOR;BIOPHYSICOCHEMICAL PROPERTIES
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 242-427 IN COMPLEX WITH CAMP;DOMAIN;SUBUNIT