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Index > Protein center > Pde4b(Gene name) > Rat
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  • Pde4b (Gene name),
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Protein name ),  PDE4B_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Pde4b;
    Protein name:
    cAMP-specific 3',5'-cyclic phosphodiesterase 4B;
    Alternative:
    DPDE4;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    736
    Sequence:
    50:
    MKKSRSVMAV | TADDNLKDYF | ECSLSKSYSS | SSYTLGIDLW | RGRRCCSGNL | 
    100:
    QLPPLSQRQS | ERARTPEGDG | ISRPTTLPLT | TLPSIAITTV | SQECFDVENG | 
    150:
    PSPGRSPLDP | QASSSSGLVL | HAAFPGHSQR | RESFLYRSDS | DYDLSPKAMS | 
    200:
    RNSSLPSEQH | GDDLIVTPFA | QVLASLRIVR | NNFTLLTNLH | GAPNKRSPAA | 
    250:
    SQAPVTRVSL | QEESYQKLAM | ETLEELDWCL | DQLETIQTYR | SVSEMASNKF | 
    300:
    KRMLNRELTH | LSEMSRSGNQ | VSEYISNTFL | DKQNDVEIPS | PTQKDREKKK | 
    350:
    KQQLMTQISG | VKKLMHSSSL | NNTSISRFGV | NTENEDHLAK | ELEDLNKWGL | 
    400:
    NIFNVAGYSH | NRPLTCIMYA | IFQERDLLKT | FKISSDTFVT | YMMTLEDHYH | 
    450:
    SDVAYHNSLH | AADVAQSTHV | LLSTPALDAV | FTDLEILAAI | FAAAIHDVDH | 
    500:
    PGVSNQFLIN | TNSELALMYN | DESVLENHHL | AVGFKLLQEE | HCDIFQNLTK | 
    550:
    KQRQTLRKMV | IDMVLATDMS | KHMSLLADLK | TMVETKKVTS | SGVLLLDNYT | 
    600:
    DRIQVLRNMV | HCADLSNPTK | SLELYRQWTD | RIMEEFFQQG | DKERERGMEI | 
    650:
    SPMCDKHTAS | VEKSQVGFID | YIVHPLWETW | ADLVQPDAQD | ILDTLEDNRN | 
    700:
    WYQSMIPQSP | SPPLDERSRD | CQGLMEKFQF | ELTLEEEDSE | GPEKEGEGPN | 
    736:
    YFSSTKTLCV | IDPENRDSLE | ETDIDIATED | KSLIDT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Cat.:
    E0433h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Cat.:
    E0433r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Cat.:
    U0433r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Cat.:
    U0433h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Cat.:
    P0433Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Cat.:
    P0433Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Monoclonal Antibody for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Protein for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Protein for Rat cAMP-specific 3',5'-cyclic phosphodiesterase 4B

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Properties and hormonal regulation of two structurally related cAMP phosphodiesterases from the rat Sertoli cell."
      Swinnen J.V. , Tsikalas K.E. , Conti M.
      J. Biol. Chem.266:18370-18377(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);INDUCTION
      tissue: Sertoli cell.
    2. 2.
      "Differential CNS expression of alternative mRNA isoforms of the mammalian genes encoding cAMP-specific phosphodiesterases."
      Bolger G.B. , Rodgers L. , Riggs M.
      Gene149:237-244(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    3. 3.
      "Structure of two rat genes coding for closely related rolipram-sensitive cAMP phosphodiesterases. Multiple mRNA variants originate from alternative splicing and multiple start sites."
      Monaco L. , Vicini E. , Conti M.
      J. Biol. Chem.269:347-357(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      strain: Wistar.
    4. 4.
      "Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3."
      Huston E. , Lumb S. , Russell A. , Catterall C. , Ross A.H. , Steele M.R. , Bolger G.B. , Perry M.J. , Owens R.J. , Houslay M.D.
      Biochem. J.328:549-558(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
      tissue: Olfactory bulb.
    5. 5.
      "Molecular cloning and subcellular distribution of the novel PDE4B4 cAMP-specific phosphodiesterase isoform."
      Shepherd M. , McSorley T. , Olsen A.E. , Johnston L.A. , Thomson N.C. , Baillie G.S. , Houslay M.D. , Bolger G.B.
      Biochem. J.370:429-438(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 4);BIOPHYSICOCHEMICAL PROPERTIES;PHOSPHORYLATION AT SER-56 (ISOFORM 4);TISSUE SPECIFICITY
      strain: Sprague-Dawley.
      tissue: Brain cortex.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5)
      tissue: Heart.
    7. 7.
      "Isolation and characterization of a mammalian gene encoding a high-affinity cAMP phosphodiesterase."
      Colicelli J. , Birchmeier C. , Michaeli T. , O'Neill K. , Riggs M. , Wigler M.
      Proc. Natl. Acad. Sci. U.S.A.86:3599-3603(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 175-736
      tissue: Brain.
    8. 8.
      "Molecular cloning of rat homologues of the Drosophila melanogaster dunce cAMP phosphodiesterase: evidence for a family of genes."
      Swinnen J.V. , Joseph D.R. , Conti M.
      Proc. Natl. Acad. Sci. U.S.A.86:5325-5329(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 304-663
      tissue: Testis.
    9. 9.
      "Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling."
      Bailey M.J. , Coon S.L. , Carter D.A. , Humphries A. , Kim J.S. , Shi Q. , Gaildrat P. , Morin F. , Ganguly S. , Hogenesch J.B. , Weller J.L. , Rath M.F. , Moller M. , Baler R. , Sugden D. , Rangel Z.G. , Munson P.J. , Klein D.C.
      J. Biol. Chem.284:7606-7622(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION
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