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Index > Protein center > Pde4d(Gene name) > Mouse
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  • Pde4d (Gene name),
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Protein name ),  PDE4D_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Pde4d;
    Protein name:
    cAMP-specific 3',5'-cyclic phosphodiesterase 4D;
    Alternative:
    DPDE3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Binds ARRB2. Interacts with PDE4DIP.
    Function:
    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
    Subcellular Location:
    Cytoplasm Membrane Cytoplasm cytoskeleton Cytoplasm cytoskeleton centrosome Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome.
    Protein Attributes:
    Sequence length:
    747
    Sequence:
    50:
    MERDTCDVLS | RSKSASEETL | HSCNEEEDPF | RGMEPYLVRR | LSSRSIQLPP | 
    100:
    LAFRQLEQAD | LRSESENIPR | PTSLPLKILP | LIAVTSADSS | GFDVDNGTSA | 
    150:
    GRSPLDPMTS | PGSGLILQAN | FVHSQRRESF | LYRSDSDYDL | SPKSMSRNSS | 
    200:
    IASDIHGDDL | IVTPFAQVLA | SLRTVRNNFA | ALTNLQDRAP | SKRSPMCNQP | 
    250:
    SINKATITEE | AYQKLASETL | EELDWCLDQL | ETLQTRHSVS | EMASNKFKRM | 
    300:
    LNRELTHLSE | MSRSGNQVSE | YISNTFLDKQ | HEVEIPSPTQ | KEKEKKKRPM | 
    350:
    SQISGVKKLM | HSSSLTNSCI | PRFGVKTEQE | DVLAKELEDV | NKWGLHVFRI | 
    400:
    AELSGNRPLT | VIMHTIFQER | DLLKTFKIPV | DTLITYLMTL | EDHYHADVAY | 
    450:
    HNNIHAADVV | QSTHVLLSTP | ALEAVFTDLE | ILAAIFASAI | HDVDHPGVSN | 
    500:
    QFLINTNSEL | ALMYNDSSVL | ENHHLAVGFK | LLQEENCDIF | QNLTKKQRQS | 
    550:
    LRKMVIDIVL | ATDMSKHMNL | LADLKTMVET | KKVTSSGVLL | LDNYSDRIQV | 
    600:
    LQNMVHCADL | SNPTKPLQLY | RQWTDRIMEE | FFRQGDRERE | RGMEISPMCD | 
    650:
    KHNASVEKSQ | VGFIDYIVHP | LWETWADLVH | PDAQDILDTL | EDNREWYQST | 
    700:
    IPQSPSPAPD | DQEEGRQGQT | EKFQFELTLE | EDCESDTEKD | SGSQVEEDTS | 
    747:
    CSDSKTLCTQ | DSESTEIPLD | EQVEEEAVAE | EESQPETCVP | DDCCPDT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    ELISA Kit for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    ELISA Kit for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    CLIA Kit for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    CLIA Kit for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    CLIA Kit for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Polyclonal Antibody for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Polyclonal Antibody for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Polyclonal Antibody for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Monoclonal Antibody for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Monoclonal Antibody for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Monoclonal Antibody for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Protein for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Protein for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Protein for Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4D

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Cloning and characterization of novel PDE4D isoforms PDE4D6 and PDE4D7."
      Wang D. , Deng C. , Bugaj-Gaweda B. , Kwan M. , Gunwaldsen C. , Leonard C. , Xin X. , Hu Y. , Unterbeck A. , De Vivo M.
      Cell. Signal.15:883-891(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 7);TISSUE SPECIFICITY
      strain: BALB/c.
    2. 2.
      Chai H. , Gaweda B. , De Vivo M. , Wang D.
      Submitted (2003-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 9)
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      strain: C57BL/6J.
      tissue: Head.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    5. 5.
      "A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs. Molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase."
      Repaske D.R. , Swinnen J.V. , Jin S.-L.C. , van Wyk J.J. , Conti M.
      J. Biol. Chem.267:18683-18688(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 400-514
    6. 6.
      "Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors."
      Lee J.H. , Richter W. , Namkung W. , Kim K.H. , Kim E. , Conti M. , Lee M.G.
      J. Biol. Chem.282:10414-10422(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SHANK2;TISSUE SPECIFICITY
    7. 7.
      "Remodeling of ryanodine receptor complex causes 'leaky' channels: a molecular mechanism for decreased exercise capacity."
      Bellinger A.M. , Reiken S. , Dura M. , Murphy P.W. , Deng S.X. , Landry D.W. , Nieman D. , Lehnart S.E. , Samaru M. , LaCampagne A. , Marks A.R.
      Proc. Natl. Acad. Sci. U.S.A.105:2198-2202(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH RYR1; FKBP1A; PKA AND PP1
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